iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089793

Ensembl Protein ID

ENSOARP00000007336.1

UniProt Accession

W5PA77; W5PA77_SHEEP

Genbank Protein ID

ENSOARP00000007336

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01004998

Gene Name

LOC101109843

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000006853.1	ENSOART00000007447.1	ENSOARP00000007336.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-34	115.2	468	501
UBD/Beta-Prp	8.50e-60	202.6	270	565

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H ++v +laf ++ ++l+s++ D  +k+WDl  g
   Q: 468  HRGPVLSLAFpPNgKYLASAGEDQRLKLWDLAPG 501
           99*********777****************9766 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkil 67
           + ++ v +spd++lla+g+++++ik+w+++++kl                                ++ l gh  +v++++f  d++ l
   Q: 270  QLLNTVEVSPDSKLLAAGFDNSCIKLWSLRSKKLksephhvnvsrihlacdfleeeddeddnagteMKVLRGHCRPVYSTRFLADSSGL 358
           5677899**********************************************************99999******************* PP
   S: 68   vtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGs 156
           +++seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+ +w  +  + l+ + +gh + v cv++hp++n+l+ Gs
   Q: 359  LSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPQSLYFASGSHDRTAWLWSFDRTYPLR-IYAGHLAEVDCVKFHPNSNYLAMGS 446
           ***************************************************************.************************* PP
   S: 157  lDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgs 245
           +D+tvrlW+ ++g+ +r +t+ h ++v sl+f +ngk+l+s+++d+++klwdl  g+  ++l+ghtd ++s  fsp++ +++s  +D+s
   Q: 447  TDKTVRLWSTQQGNSVRLFTS-HRGPVLSLAFPPNGKYLASAGEDQRLKLWDLAPGTLYKELRGHTDSITSFTFSPDSSLFAS--MDNS 532
           ********************9.*****************************************************99988876..69** PP
   S: 246  iriWdlrsgdllktlqlhnssvisvavlsfgdn 278
           + +Wd+rs  + + + ++ s+ + v + ++++ 
   Q: 533  VLVWDIRSVHCSTPTDGSSSKPVGVYTSEMSNV 565
           ************999999866666666444443 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

VMKWVHTEQI QMAVSCYLKR RQYGDAVGPL KQGLRLSQST EEMAASLTVQ SESGCTNIVS 60
AAPCQAEPQQ YEVQFGRLRN FLTDSDSQHS HEVMPLLYPL FVYLHLNLIQ NSPKSTVESF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCATGAAAT GGGTCCACAC GGAGCAGATC CAGATGGCCG TGTCCTGCTA CCTCAAACGC 60
CGGCAGTACG GGGATGCGGT CGGCCCGCTG AAGCAAGGCC TGCGGCTGTC GCAGAGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	90.49	0.00e+00	1014.00
IUUC-Apl-003636	Anas platyrhynchos	85.62	0.00e+00	1028.00
IUUC-Aca-004229	Anolis carolinensis	85.06	0.00e+00	994.00
IUUC-Ame-010599	Astyanax mexicanus	63.74	0.00e+00	757.00
IUUC-Bta-013404	Bos taurus	92.87	0.00e+00	1022.00
IUUC-Cja-019643	Callithrix jacchus	90.32	0.00e+00	1018.00
IUUC-Cfa-020913	Canis familiaris	90.68	0.00e+00	1019.00
IUUC-Cpo-021777	Cavia porcellus	87.95	0.00e+00	991.00
IUUC-Csa-024184	Chlorocebus sabaeus	89.98	0.00e+00	1016.00
IUUC-Cho-024638	Choloepus hoffmanni	89.47	0.00e+00	1004.00
IUUC-Dre-028817	Danio rerio	62.46	0.00e+00	750.00
IUUC-Dno-029969	Dasypus novemcinctus	83.56	0.00e+00	957.00
IUUC-Dor-031117	Dipodomys ordii	87.95	0.00e+00	1021.00
IUUC-Ete-032712	Echinops telfairi	82.51	0.00e+00	905.00
IUUC-Eca-033742	Equus caballus	90.32	0.00e+00	1015.00
IUUC-Eeu-035096	Erinaceus europaeus	87.97	0.00e+00	1024.00
IUUC-Fca-035769	Felis catus	90.02	0.00e+00	1036.00
IUUC-Fal-036645	Ficedula albicollis	85.43	0.00e+00	969.00
IUUC-Gmo-038636	Gadus morhua	61.50	0.00e+00	726.00
IUUC-Gga-040144	Gallus gallus	85.91	0.00e+00	1001.00
IUUC-Gac-041716	Gasterosteus aculeatus	65.22	0.00e+00	754.00
IUUC-Ggo-044568	Gorilla gorilla	90.15	0.00e+00	1016.00
IUUC-Hsa-046178	Homo sapiens	90.15	0.00e+00	1016.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	84.72	0.00e+00	998.00
IUUC-Lch-050501	Latimeria chalumnae	72.34	0.00e+00	796.00
IUUC-Loc-052895	Lepisosteus oculatus	77.66	1.00e-170	592.00
IUUC-Laf-053950	Loxodonta africana	86.08	0.00e+00	985.00
IUUC-Mcc-055450	Macaca mulatta	89.98	0.00e+00	1012.00
IUUC-Meu-056182	Macropus eugenii	82.00	0.00e+00	934.00
IUUC-Mga-059619	Meleagris gallopavo	86.08	0.00e+00	1004.00
IUUC-Mmr-061074	Microcebus murinus	88.83	0.00e+00	1025.00
IUUC-Mdo-062307	Monodelphis domestica	88.75	0.00e+00	847.00
IUUC-Mmu-063226	Mus musculus	86.76	0.00e+00	971.00
IUUC-Mpu-066016	Mustela putorius furo	90.15	0.00e+00	1014.00
IUUC-Mlu-067257	Myotis lucifugus	82.64	0.00e+00	995.00
IUUC-Nle-070139	Nomascus leucogenys	89.98	0.00e+00	1015.00
IUUC-Opr-070243	Ochotona princeps	85.91	0.00e+00	998.00
IUUC-Ont-072686	Oreochromis niloticus	66.22	0.00e+00	776.00
IUUC-Oan-073670	Ornithorhynchus anatinus	78.27	0.00e+00	770.00
IUUC-Ocu-074525	Oryctolagus cuniculus	89.32	0.00e+00	1035.00
IUUC-Ola-086524	Oryzias latipes	65.89	0.00e+00	796.00
IUUC-Oga-088540	Otolemur garnettii	89.47	0.00e+00	1005.00
IUUC-Ptr-091154	Pan troglodytes	90.15	0.00e+00	1016.00
IUUC-Pan-092759	Papio anubis	89.98	0.00e+00	1012.00
IUUC-Psi-094008	Pelodiscus sinensis	84.04	0.00e+00	996.00
IUUC-Pma-094593	Petromyzon marinus	43.63	4.00e-121	428.00
IUUC-Pfo-097409	Poecilia formosa	64.89	0.00e+00	755.00
IUUC-Pab-097946	Pongo abelii	78.27	0.00e+00	859.00
IUUC-Pca-100727	Procavia capensis	82.51	0.00e+00	909.00
IUUC-Pva-103211	Pteropus vampyrus	80.31	0.00e+00	936.00
IUUC-Rno-105236	Rattus norvegicus	86.76	0.00e+00	967.00
IUUC-Sha-106833	Sarcophilus harrisii	86.66	0.00e+00	1008.00
IUUC-Sar-113381	Sorex araneus	90.15	0.00e+00	1045.00
IUUC-Ssc-116421	Sus scrofa	91.34	0.00e+00	1076.00
IUUC-Tgu-117143	Taeniopygia guttata	86.08	0.00e+00	1034.00
IUUC-Tru-118680	Takifugu rubripes	65.33	0.00e+00	775.00
IUUC-Tsy-119622	Tarsius syrichta	74.87	0.00e+00	764.00
IUUC-Tni-120131	Tetraodon nigroviridis	64.73	0.00e+00	777.00
IUUC-Ttr-129171	Tursiops truncatus	92.02	0.00e+00	1023.00
IUUC-Xtr-132241	Xenopus tropicalis	75.93	0.00e+00	879.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence