iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013482

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Proteasomal ATPase-associated factor 1; WD repeat-containing protein 71

Genbank Nucleotide ID

BC118307

Gene Name

PAAF1; WDR71

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000003679.4	ENSBTAT00000004794.4	ENSBTAP00000004794.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-17	62.9	174	205

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH++++ + a    ++ +vsGs+Dgt ++WD 
   Q: 174  GHKGGILDTAIvdRGKNVVSGSRDGTARLWDC 205
           899999999997544789*************6 PP

Organism

Bos taurus

Functional Description
(View)

Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Protects SUPT6H from proteasomal degradation (By similarity).

Protein Sequence
(Fasta)

MAAPLRIQSD WAQALRKDEG EAWLSCHPPG KPTLYGSLTC QGIGLDGIPE VTASEGFIVN 60
EINKKSIHVS CPKENVSSKF LAPYTTFSRI HTKSITCLDI SSGGGLGVSS SADGSMKIWQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGGTTAA GATGGCGGCA CCTTTGAGGA TTCAGAGCGA CTGGGCCCAG GCTCTCAGGT 60
GAATCCAGGT CCAGAACTGG GACATAGGAG GCGGGTAGCG GATGTTGCCT TTACGTTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000502--C:proteasome complex

KEGG

bta:533348

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002247	Ailuropoda melanoleuca	96.17	0.00e+00	750.00
IUUC-Apl-003653	Anas platyrhynchos	78.16	3.00e-154	537.00
IUUC-Aca-004747	Anolis carolinensis	78.72	0.00e+00	642.00
IUUC-Ago-007984	Ashbya gossypii	26.70	1.00e-24	107.00
IUUC-Cel-018693	Caenorhabditis elegans	25.69	1.00e-27	117.00
IUUC-Cja-018842	Callithrix jacchus	95.15	0.00e+00	749.00
IUUC-Cfa-020708	Canis familiaris	95.92	0.00e+00	752.00
IUUC-Cpo-021469	Cavia porcellus	94.90	0.00e+00	748.00
IUUC-Csa-024109	Chlorocebus sabaeus	95.66	0.00e+00	749.00
IUUC-Cin-025576	Ciona intestinalis	44.33	3.00e-82	298.00
IUUC-Dno-029167	Dasypus novemcinctus	93.37	0.00e+00	737.00
IUUC-Dor-030470	Dipodomys ordii	58.36	6.00e-109	387.00
IUUC-Ete-033078	Echinops telfairi	76.27	1.00e-75	276.00
IUUC-Eca-034292	Equus caballus	86.29	0.00e+00	662.00
IUUC-Eeu-035251	Erinaceus europaeus	92.88	0.00e+00	715.00
IUUC-Fca-035982	Felis catus	96.68	0.00e+00	754.00
IUUC-Fal-036938	Ficedula albicollis	78.35	4.00e-172	597.00
IUUC-Gga-040796	Gallus gallus	81.89	0.00e+00	656.00
IUUC-Ggo-044448	Gorilla gorilla	83.97	8.00e-145	506.00
IUUC-Hsa-046552	Homo sapiens	94.26	0.00e+00	625.00
IUUC-Itr-048359	Ictidomys tridecemlineatus	94.56	1.00e-177	615.00
IUUC-Lch-050291	Latimeria chalumnae	64.29	3.00e-133	468.00
IUUC-Loc-052254	Lepisosteus oculatus	70.66	3.00e-165	574.00
IUUC-Laf-053334	Loxodonta africana	94.13	0.00e+00	737.00
IUUC-Mcc-055257	Macaca mulatta	95.66	0.00e+00	749.00
IUUC-Meu-056613	Macropus eugenii	86.48	1.00e-138	485.00
IUUC-Mga-059647	Meleagris gallopavo	82.14	0.00e+00	655.00
IUUC-Mvi-060210	Microbotryum violaceum	24.88	7.00e-16	78.60
IUUC-Mmr-061119	Microcebus murinus	96.43	0.00e+00	756.00
IUUC-Mdo-062819	Monodelphis domestica	82.75	0.00e+00	677.00
IUUC-Mpu-066654	Mustela putorius furo	89.82	0.00e+00	689.00
IUUC-Mlu-067875	Myotis lucifugus	96.43	0.00e+00	749.00
IUUC-Nle-069290	Nomascus leucogenys	95.66	0.00e+00	751.00
IUUC-Opr-070348	Ochotona princeps	79.08	0.00e+00	631.00
IUUC-Oan-072693	Ornithorhynchus anatinus	76.65	5.00e-167	580.00
IUUC-Ocu-074103	Oryctolagus cuniculus	92.41	0.00e+00	731.00
IUUC-Oga-089096	Otolemur garnettii	93.99	2.00e-177	614.00
IUUC-Oar-089389	Ovis aries	98.47	0.00e+00	764.00
IUUC-Ptr-090483	Pan troglodytes	96.43	0.00e+00	754.00
IUUC-Pan-091915	Papio anubis	95.81	1.00e-111	395.00
IUUC-Psi-093034	Pelodiscus sinensis	82.28	5.00e-180	623.00
IUUC-Pab-097969	Pongo abelii	96.43	0.00e+00	757.00
IUUC-Pca-100381	Procavia capensis	86.99	0.00e+00	676.00
IUUC-Pva-103127	Pteropus vampyrus	95.79	2.00e-120	425.00
IUUC-Sce-106259	Saccharomyces cerevisiae	28.98	4.00e-23	102.00
IUUC-Sha-106604	Sarcophilus harrisii	87.24	0.00e+00	706.00
IUUC-Sar-113535	Sorex araneus	91.88	0.00e+00	691.00
IUUC-Ssc-115947	Sus scrofa	96.43	0.00e+00	749.00
IUUC-Tgu-117085	Taeniopygia guttata	80.94	7.00e-160	556.00
IUUC-Tsy-119428	Tarsius syrichta	93.29	4.00e-79	288.00
IUUC-Tbe-127687	Tupaia belangeri	57.02	3.00e-58	219.00
IUUC-Ttr-129277	Tursiops truncatus	90.91	4.00e-116	410.00
IUUC-Vpa-130349	Vicugna pacos	85.97	0.00e+00	642.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence