iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034416

UUCD1 version

UUC-EqC-01053

Ensembl Protein ID

ENSECAP00000007415.1

UniProt Accession

F6YRH0; F6YRH0_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000009333.1	ENSECAT00000009697.1	ENSECAP00000007415.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.10e-83	278.7	467	970

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 467  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 544
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e+ + ++++l++         ++  +   +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 545  QDCSEYLRFLLDRLHEEEKIlkvQSSHKPSESLGCSETSLQEVagkaafltESPCTSDGEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 633
           *****************95577778888888888888888888999999988888888999**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  ++ ++++                                                                       
   Q: 634  AFTDLSLAFCPSSLENLSfqdpalspntqgggllrasvpgpseelgvynpataafvcdsavnermvgsppdefcctentsvpnesskil 722
           *************88888*********************************************************************** PP
   S: 186  ...............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
                          s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L
   Q: 723  vnkdvphkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVL 811
           ****************************************************************************************9 PP
   S: 260  dlspfctspeekqke...............................kkkYeLiavvvHsG.slssGHYvayvkn............... 301
           +l    t++ ++ +e                                + Y L++vvvHsG s++sGHY++y++n               
   Q: 812  ELPVKRTTSFSSLSEswsidvdftdisenlakklkpsgteevccprLVPYLLSSVVVHSGiSSESGHYYSYARNitgsessyqvchqse 900
           99965555333333355666666666666666777777778888889****************************************** PP
   S: 302  .............................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                         +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 901  tlalassrshllgrdspsavieqdlenkeMSKEWFLFNDSRVTFTSFHSVQKITSrfpkDTAYVLLYKKQ 970
           *****9999999999999999988865544555*******************999************986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

APPRGCGLPL LTPWPWPCCV ATMDKILEGL VSSSHPLSLK RMIVRKVVES AEHWLDKAQC 60
EAMFDLTTRL ILEGQDPFQR QVGHQVLEAY ARYHRPEFES FFNKTFVLGL LQQGYHSLDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTCACCTCC GCCGCGAGCT CTTCTGCTCC ACCTCGGGGC TGTGGCCTAC CGCTCCTTAC 60
CCCCTGGCCC TGGCCTTGCT GTGTGGCGAC AATGGACAAG ATCCTGGAGG GCCTGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	94.75	0.00e+00	1878.00
IUUC-Apl-003435	Anas platyrhynchos	76.44	0.00e+00	1258.00
IUUC-Aca-004556	Anolis carolinensis	70.59	0.00e+00	1284.00
IUUC-Ame-010616	Astyanax mexicanus	62.23	0.00e+00	1222.00
IUUC-Bta-013544	Bos taurus	94.15	0.00e+00	1844.00
IUUC-Cja-018745	Callithrix jacchus	92.73	0.00e+00	1875.00
IUUC-Cfa-020434	Canis familiaris	90.69	0.00e+00	1803.00
IUUC-Cpo-021666	Cavia porcellus	92.03	0.00e+00	1783.00
IUUC-Csa-023965	Chlorocebus sabaeus	94.15	0.00e+00	1944.00
IUUC-Cho-024809	Choloepus hoffmanni	85.94	0.00e+00	1300.00
IUUC-Cin-025604	Ciona intestinalis	29.78	3.00e-40	159.00
IUUC-Csv-026333	Ciona savignyi	44.00	1.00e-30	126.00
IUUC-Dre-028338	Danio rerio	62.46	0.00e+00	1233.00
IUUC-Dno-029372	Dasypus novemcinctus	92.61	0.00e+00	1854.00
IUUC-Dor-030752	Dipodomys ordii	89.47	0.00e+00	1244.00
IUUC-Dme-031871	Drosophila melanogaster	31.01	1.00e-45	178.00
IUUC-Ete-032588	Echinops telfairi	80.91	0.00e+00	1148.00
IUUC-Eeu-035132	Erinaceus europaeus	74.93	0.00e+00	1410.00
IUUC-Fca-036137	Felis catus	95.20	0.00e+00	1920.00
IUUC-Fal-037297	Ficedula albicollis	75.55	0.00e+00	1434.00
IUUC-Gmo-038727	Gadus morhua	65.66	0.00e+00	1003.00
IUUC-Gga-041091	Gallus gallus	73.88	0.00e+00	1388.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.21	0.00e+00	1118.00
IUUC-Ggo-045376	Gorilla gorilla	89.00	0.00e+00	1798.00
IUUC-Hsa-046444	Homo sapiens	94.24	0.00e+00	1908.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	93.40	0.00e+00	1932.00
IUUC-Lch-050500	Latimeria chalumnae	72.49	0.00e+00	1424.00
IUUC-Loc-052625	Lepisosteus oculatus	64.56	0.00e+00	1290.00
IUUC-Laf-053689	Loxodonta africana	94.13	0.00e+00	1887.00
IUUC-Mcc-055286	Macaca mulatta	94.43	0.00e+00	1919.00
IUUC-Mga-059905	Meleagris gallopavo	74.59	0.00e+00	1228.00
IUUC-Mmr-061397	Microcebus murinus	94.63	0.00e+00	1897.00
IUUC-Mdo-062833	Monodelphis domestica	86.79	0.00e+00	1796.00
IUUC-Mmu-063157	Mus musculus	90.02	0.00e+00	1805.00
IUUC-Mpu-066434	Mustela putorius furo	95.87	0.00e+00	1943.00
IUUC-Mlu-068178	Myotis lucifugus	92.95	0.00e+00	1826.00
IUUC-Nle-070153	Nomascus leucogenys	93.86	0.00e+00	1845.00
IUUC-Ont-072330	Oreochromis niloticus	62.90	0.00e+00	1229.00
IUUC-Oan-072709	Ornithorhynchus anatinus	81.64	0.00e+00	1295.00
IUUC-Ocu-074832	Oryctolagus cuniculus	94.34	0.00e+00	1882.00
IUUC-Ola-087003	Oryzias latipes	55.67	1.00e-49	188.00
IUUC-Oga-088517	Otolemur garnettii	89.19	0.00e+00	1816.00
IUUC-Oar-089472	Ovis aries	90.81	0.00e+00	1805.00
IUUC-Ptr-090996	Pan troglodytes	93.86	0.00e+00	1901.00
IUUC-Pan-091837	Papio anubis	92.28	0.00e+00	1892.00
IUUC-Psi-093236	Pelodiscus sinensis	76.81	0.00e+00	1170.00
IUUC-Pma-094349	Petromyzon marinus	52.91	0.00e+00	973.00
IUUC-Pfo-097193	Poecilia formosa	62.16	0.00e+00	1140.00
IUUC-Pab-098710	Pongo abelii	94.05	0.00e+00	1922.00
IUUC-Pca-100794	Procavia capensis	82.74	0.00e+00	1640.00
IUUC-Pva-102722	Pteropus vampyrus	94.06	0.00e+00	1898.00
IUUC-Rno-105743	Rattus norvegicus	88.77	0.00e+00	1771.00
IUUC-Sha-106563	Sarcophilus harrisii	85.60	0.00e+00	1451.00
IUUC-Sar-113533	Sorex araneus	78.04	0.00e+00	1554.00
IUUC-Ssc-116259	Sus scrofa	84.23	0.00e+00	1623.00
IUUC-Tgu-117475	Taeniopygia guttata	75.58	0.00e+00	1308.00
IUUC-Tru-118623	Takifugu rubripes	62.85	0.00e+00	1145.00
IUUC-Tsy-119250	Tarsius syrichta	92.63	0.00e+00	1484.00
IUUC-Tni-120441	Tetraodon nigroviridis	58.79	0.00e+00	1056.00
IUUC-Tbe-127936	Tupaia belangeri	80.52	0.00e+00	1537.00
IUUC-Ttr-128483	Tursiops truncatus	81.77	0.00e+00	1430.00
IUUC-Vpa-130303	Vicugna pacos	98.13	0.00e+00	1068.00
IUUC-Xtr-132773	Xenopus tropicalis	72.13	0.00e+00	1400.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence