iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-002048

Ensembl Protein ID

ENSAMEP00000002142.1

UniProt Accession

G1L5I1; G1L5I1_AILME

Genbank Protein ID

ENSAMEP00000002142

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01080008

Gene Name

CFAP52

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000001999.1	ENSAMET00000002233.1	ENSAMEP00000002142.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-32	108.6	460	491
UBD/Beta-Prp	6.70e-58	196.3	171	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlr 31
           H++sv+c++   ++   v++s Dgt+ +WDl 
   Q: 460  HKSSVSCIRVkkNNEECVTASTDGTCIIWDLV 491
           9**********87799**************85 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl.................lrslsgheae.................................vtavkf 60
           +++++t++ +gti+vw+++ ++                    ++ +++++                                 v+a+k+
   Q: 171  DEMFVTAG-NGTIRVWELDLPNRkiwptecqtgqmkrivmSITMADDDSFfylgtttgdilkmnprtklladtgpakdkfslgVSAIKC 258
           45566665.*********99998777777777776666543333333333788888888888888888888888899999999777777 PP
   S: 61   spdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg 149
            + g  l+ gs+ +++      ++k++ +++  +  ++s+++  +g+ + +G++ + i   +    ++   + + h ++v+ +v+++ +
   Q: 259  LKMG-GLLVGSRAGLLVFCKSPSYKPIKKIQ-LQGGITSITLRGEGHQFFVGTEESHIYRVNFTDFKETL-IATCHCEAVQDIVFPSGT 344
           7776.45666666555444666888888888.88888888888888888888877777666666666666.888888888888888877 PP
   S: 150  .nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng.htdnvksvrfspnder 236
            +l++++++ + +r+W   +++ l + t   +   + ++f ++gk+++s+ +dg+++ +  +tg+ ++  n+ h+  v+ ++++++ +r
   Q: 345  tDLFATCAK-KDIRVWHTLSNRELLRITV-PNTTCHGIDFMRDGKSIISAWDDGRIRAFAPETGRLMYVINNaHRIGVTAIATTSDCKR 431
           566666654.6788888766666666665.67778888888888888888888888888888888766655448888888888888888 PP
   S: 237  lvsgssDgsiriW..dlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           ++sg+ +g +r+W   +++++l  +l+ h+ssv+++ v + ++ ++v++s d++  iw+l
   Q: 432  VISGGGEGEVRVWqiGCQTQKLEEALKEHKSSVSCIRV-KKNNEECVTASTDGTCIIWDL 490
           88888888888888888888888888888888888888.777888888888888888876 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MENQVSLKAE VAELELEAVI GFNGHVPTGL KCHPDQEHVI YPLGCTVLIQ AINTQEQNFL 60
HGHDNNVSCV TISKSGVYLA SGQVTFMGFK ADIILWDYKK RELIARLSLH KGKIEALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAACC AAGTTTCGCT CAAAGCCGAG GTGGCGGAGC TGGAGCTTGA GGCCGTCATC 60
GGCTTCAACG GTGAGGCCTC GAGCGTGTCT GGGCTGGGCG GTTTGCAAGC CCCGGGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033015--CFAP52
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

aml:100472266

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004011	Anas platyrhynchos	71.31	0.00e+00	914.00
IUUC-Aca-004805	Anolis carolinensis	74.18	0.00e+00	961.00
IUUC-Ame-010655	Astyanax mexicanus	61.99	0.00e+00	793.00
IUUC-Bta-013493	Bos taurus	94.34	0.00e+00	1165.00
IUUC-Cja-019923	Callithrix jacchus	92.42	0.00e+00	1176.00
IUUC-Cfa-020609	Canis familiaris	95.81	0.00e+00	1192.00
IUUC-Cpo-021926	Cavia porcellus	91.18	0.00e+00	1137.00
IUUC-Cre-022705	Chlamydomonas reinhardtii	44.74	1.00e-159	556.00
IUUC-Csa-023338	Chlorocebus sabaeus	92.90	0.00e+00	1184.00
IUUC-Cho-024884	Choloepus hoffmanni	86.27	0.00e+00	724.00
IUUC-Cin-025634	Ciona intestinalis	62.97	0.00e+00	807.00
IUUC-Csv-026211	Ciona savignyi	64.61	8.00e-96	342.00
IUUC-Dre-028268	Danio rerio	64.48	0.00e+00	871.00
IUUC-Dno-029202	Dasypus novemcinctus	86.19	0.00e+00	1048.00
IUUC-Dor-030197	Dipodomys ordii	79.23	0.00e+00	747.00
IUUC-Dme-032037	Drosophila melanogaster	35.80	3.00e-111	396.00
IUUC-Ete-033049	Echinops telfairi	83.05	0.00e+00	992.00
IUUC-Eca-033884	Equus caballus	95.32	0.00e+00	1190.00
IUUC-Eeu-034477	Erinaceus europaeus	81.20	2.00e-180	625.00
IUUC-Fca-035453	Felis catus	93.61	0.00e+00	1172.00
IUUC-Gmo-039448	Gadus morhua	64.39	2.00e-110	393.00
IUUC-Gga-040295	Gallus gallus	71.69	0.00e+00	942.00
IUUC-Gac-042074	Gasterosteus aculeatus	55.43	0.00e+00	699.00
IUUC-Ggo-044438	Gorilla gorilla	93.39	0.00e+00	914.00
IUUC-Hsa-046794	Homo sapiens	92.42	0.00e+00	1176.00
IUUC-Itr-048315	Ictidomys tridecemlineatus	93.95	0.00e+00	684.00
IUUC-Lch-050554	Latimeria chalumnae	65.74	0.00e+00	809.00
IUUC-Loc-052080	Lepisosteus oculatus	69.24	0.00e+00	907.00
IUUC-Laf-054288	Loxodonta africana	93.71	0.00e+00	1166.00
IUUC-Mcc-055746	Macaca mulatta	86.13	0.00e+00	1069.00
IUUC-Meu-056507	Macropus eugenii	74.63	2.00e-148	519.00
IUUC-Mga-059858	Meleagris gallopavo	71.40	0.00e+00	901.00
IUUC-Mmr-061757	Microcebus murinus	94.59	0.00e+00	1028.00
IUUC-Mdo-062670	Monodelphis domestica	83.20	0.00e+00	1085.00
IUUC-Mmu-064084	Mus musculus	92.10	0.00e+00	1175.00
IUUC-Mpu-066253	Mustela putorius furo	95.32	0.00e+00	1178.00
IUUC-Mlu-067944	Myotis lucifugus	75.51	0.00e+00	916.00
IUUC-Nle-069098	Nomascus leucogenys	92.74	0.00e+00	1176.00
IUUC-Opr-070525	Ochotona princeps	83.83	0.00e+00	912.00
IUUC-Ont-071609	Oreochromis niloticus	59.05	0.00e+00	768.00
IUUC-Oan-073543	Ornithorhynchus anatinus	78.90	0.00e+00	1018.00
IUUC-Ocu-074209	Oryctolagus cuniculus	91.94	0.00e+00	1178.00
IUUC-Ola-086464	Oryzias latipes	56.05	0.00e+00	726.00
IUUC-Olu-087600	Ostreococcus lucimarinus	33.33	5.00e-93	335.00
IUUC-Oga-088977	Otolemur garnettii	90.32	0.00e+00	1152.00
IUUC-Oar-089192	Ovis aries	94.01	0.00e+00	1165.00
IUUC-Ptr-090882	Pan troglodytes	87.94	0.00e+00	1085.00
IUUC-Pan-092865	Papio anubis	88.41	0.00e+00	1118.00
IUUC-Psi-093270	Pelodiscus sinensis	77.11	0.00e+00	867.00
IUUC-Pma-094291	Petromyzon marinus	63.30	0.00e+00	850.00
IUUC-Ppa-095984	Physcomitrella patens	42.51	4.00e-147	514.00
IUUC-Pfo-097344	Poecilia formosa	51.24	0.00e+00	679.00
IUUC-Pab-098278	Pongo abelii	92.58	0.00e+00	1175.00
IUUC-Pca-101037	Procavia capensis	94.13	0.00e+00	1156.00
IUUC-Pva-102351	Pteropus vampyrus	93.45	0.00e+00	976.00
IUUC-Rno-105262	Rattus norvegicus	91.77	0.00e+00	1173.00
IUUC-Smo-109009	Selaginella moellendorffii	44.33	1.00e-162	566.00
IUUC-Sar-113156	Sorex araneus	79.81	1.00e-141	496.00
IUUC-Ssc-116319	Sus scrofa	95.12	2.00e-67	246.00
IUUC-Tru-117963	Takifugu rubripes	54.66	0.00e+00	711.00
IUUC-Tsy-119115	Tarsius syrichta	71.48	0.00e+00	807.00
IUUC-Tni-120388	Tetraodon nigroviridis	53.34	0.00e+00	679.00
IUUC-Tbe-127930	Tupaia belangeri	82.34	5.00e-180	624.00
IUUC-Ttr-128981	Tursiops truncatus	92.95	0.00e+00	1120.00
IUUC-Vpa-130492	Vicugna pacos	85.91	0.00e+00	1057.00
IUUC-Xtr-132142	Xenopus tropicalis	68.90	0.00e+00	922.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence