iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053978

Ensembl Protein ID

ENSLAFP00000020398.1

UniProt Accession

G3TXU0; G3TXU0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

BCAR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000030093.1	ENSLAFT00000033322.1	ENSLAFP00000027545.1
ENSLAFG00000030093.1	ENSLAFT00000036502.1	ENSLAFP00000020398.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.20e-11	43.0	8	58

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeq.degWlkgvkelegkrGlfPen 57
            ++lyd  a++ deL+++kGd+++v+e ++q   gW+ +   l+g++G++P n
   Q: 8    AKALYDNVAESPDELSFRKGDIMTVLERDTQgLDGWWLC--SLHGRQGIVPGN 58
           689***********************55555168*****..9*********98 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LSPQNVLAKA LYDNVAESPD ELSFRKGDIM TVLERDTQGL DGWWLCSLHG RQGIVPGNRL 60
KILVGMYDKK PSGPGSGLPT TPAQPILHAA VMPPASQYTP MLPATYQSPP DNVYLVPTPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCATTTC TCATCAGTTA ATCATTCTTG TTTGTTGGAT TTTCTGTGTA GATGATCATC 60
TGGGCTGCAA ATGATGTCAG TTTTGTCCCC GTCTTTCTCT CTCTCTCTCT CTCTCTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028848--BCAR1
IPR021901--CAS_DUF3513
IPR014928--Serine_rich
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
IPR015224--Talin_cent

PROSITE

PS50002--SH3

Pfam

PF12026--DUF3513
PF08824--Serine_rich
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004871--F:signal transducer activity
GO:0007015--P:actin filament organization
GO:0050853--P:B cell receptor signaling pathway
GO:0060326--P:cell chemotaxis
GO:0035729--P:cellular response to hepatocyte growth factor stimulus
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0048012--P:hepatocyte growth factor receptor signaling pathway
GO:0007229--P:integrin-mediated signaling pathway
GO:0048008--P:platelet-derived growth factor receptor signaling pathway
GO:0010595--P:positive regulation of endothelial cell migration
GO:0048010--P:vascular endothelial growth factor receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001208	Ailuropoda melanoleuca	89.62	0.00e+00	1163.00
IUUC-Apl-003391	Anas platyrhynchos	37.29	8.00e-140	491.00
IUUC-Aca-004548	Anolis carolinensis	36.88	2.00e-139	489.00
IUUC-Ame-010839	Astyanax mexicanus	27.47	4.00e-29	123.00
IUUC-Bta-013197	Bos taurus	83.39	0.00e+00	1139.00
IUUC-Cja-018921	Callithrix jacchus	90.46	0.00e+00	1306.00
IUUC-Cfa-020772	Canis familiaris	91.96	0.00e+00	1265.00
IUUC-Cpo-022455	Cavia porcellus	88.67	0.00e+00	1280.00
IUUC-Csa-023660	Chlorocebus sabaeus	91.23	0.00e+00	1277.00
IUUC-Cin-025595	Ciona intestinalis	27.71	2.00e-68	253.00
IUUC-Dre-028389	Danio rerio	52.48	0.00e+00	816.00
IUUC-Dno-028907	Dasypus novemcinctus	87.51	0.00e+00	1135.00
IUUC-Dor-030300	Dipodomys ordii	94.12	2.00e-163	569.00
IUUC-Dme-031580	Drosophila melanogaster	28.47	4.00e-38	153.00
IUUC-Ete-032641	Echinops telfairi	97.46	3.00e-128	452.00
IUUC-Eca-033297	Equus caballus	91.39	0.00e+00	1274.00
IUUC-Eeu-035356	Erinaceus europaeus	83.58	0.00e+00	894.00
IUUC-Fca-036302	Felis catus	90.33	0.00e+00	1177.00
IUUC-Fal-036729	Ficedula albicollis	62.69	0.00e+00	1035.00
IUUC-Gga-040285	Gallus gallus	61.80	0.00e+00	978.00
IUUC-Gac-041754	Gasterosteus aculeatus	25.59	2.00e-21	97.80
IUUC-Ggo-045534	Gorilla gorilla	91.00	0.00e+00	1290.00
IUUC-Hsa-046672	Homo sapiens	91.35	0.00e+00	1275.00
IUUC-Itr-048045	Ictidomys tridecemlineatus	89.91	0.00e+00	1229.00
IUUC-Lch-049837	Latimeria chalumnae	58.36	0.00e+00	908.00
IUUC-Loc-052010	Lepisosteus oculatus	54.54	0.00e+00	844.00
IUUC-Mcc-055551	Macaca mulatta	91.00	0.00e+00	1250.00
IUUC-Meu-056006	Macropus eugenii	67.16	0.00e+00	949.00
IUUC-Mga-060136	Meleagris gallopavo	39.53	1.00e-147	517.00
IUUC-Mmr-061269	Microcebus murinus	89.72	0.00e+00	1324.00
IUUC-Mdo-062756	Monodelphis domestica	25.50	6.00e-29	122.00
IUUC-Mmu-063741	Mus musculus	89.32	0.00e+00	1270.00
IUUC-Mpu-066694	Mustela putorius furo	88.49	0.00e+00	1175.00
IUUC-Mlu-067377	Myotis lucifugus	88.95	0.00e+00	1251.00
IUUC-Nle-069243	Nomascus leucogenys	89.73	0.00e+00	662.00
IUUC-Opr-070611	Ochotona princeps	84.20	0.00e+00	1125.00
IUUC-Ont-071724	Oreochromis niloticus	51.29	0.00e+00	769.00
IUUC-Oan-073477	Ornithorhynchus anatinus	51.67	3.00e-45	173.00
IUUC-Ocu-074436	Oryctolagus cuniculus	80.90	0.00e+00	1087.00
IUUC-Ola-086487	Oryzias latipes	48.23	0.00e+00	709.00
IUUC-Oga-088966	Otolemur garnettii	91.63	0.00e+00	1357.00
IUUC-Oar-089394	Ovis aries	79.73	6.00e-135	474.00
IUUC-Ptr-090896	Pan troglodytes	91.46	0.00e+00	1304.00
IUUC-Pan-092021	Papio anubis	90.93	0.00e+00	1249.00
IUUC-Psi-094075	Pelodiscus sinensis	28.39	2.00e-68	253.00
IUUC-Pfo-096333	Poecilia formosa	47.69	2.00e-30	128.00
IUUC-Pab-098732	Pongo abelii	87.21	0.00e+00	1164.00
IUUC-Pca-100841	Procavia capensis	94.18	0.00e+00	660.00
IUUC-Pva-102291	Pteropus vampyrus	83.91	0.00e+00	841.00
IUUC-Rno-105602	Rattus norvegicus	89.22	0.00e+00	1268.00
IUUC-Sha-106605	Sarcophilus harrisii	58.77	9.00e-90	325.00
IUUC-Spo-108375	Schizosaccharomyces pombe	41.82	9.00e-08	53.10
IUUC-Ssc-116113	Sus scrofa	88.02	0.00e+00	1183.00
IUUC-Tgu-117420	Taeniopygia guttata	37.73	2.00e-143	503.00
IUUC-Tru-118044	Takifugu rubripes	46.76	3.00e-31	129.00
IUUC-Ttr-128533	Tursiops truncatus	88.32	0.00e+00	1167.00
IUUC-Xtr-132220	Xenopus tropicalis	30.45	6.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence