iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aly-005653

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

GL348719

Gene Name

ARALYDRAFT_915957

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
scaffold_703699.1	scaffold_703699.1	scaffold_703699.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	76.30	8.00e-125	443.00	IUUC-Ath-007187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis lyrata

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MVGAAISESS GEGIGSNSIL SQKRQLSSSD GAKRDAKKRS IMLMELEILD CPICYEAFTI 60
PIFQCDNGHL ACSSCCPKLN NKCPACASPV GHNRCRAMES VLESILVPCP NAKLGCTKKF 120

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Nucleotide Sequence
(Fasta)

TTAGGGTTTA GCCATCTCTC CGATATGGTT GGAGCCGCGA TTTCGGAATC TTCCGGCGAA 60
GGAATTGGAT CTAACAGCAT TCTCTCGCAA AAGAGACAAC TTTCTTCCAG TGATGGAGCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR001370--BIR_rpt
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_915957

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-007187	Arabidopsis thaliana	76.92	3.00e-134	470.00
IUUC-Bdi-014026	Brachypodium distachyon	34.76	3.00e-27	114.00
IUUC-Bol-016089	Brassica oleracea	65.04	8.00e-93	332.00
IUUC-Bra-016844	Brassica rapa	64.06	1.00e-94	338.00
IUUC-Hvu-047394	Hordeum vulgare	33.95	9.00e-27	113.00
IUUC-Mtr-058360	Medicago truncatula	35.56	1.00e-37	149.00
IUUC-Oan-072802	Ornithorhynchus anatinus	32.00	1.00e-04	40.80
IUUC-Opu-083398	Oryza punctata	31.20	4.00e-25	108.00
IUUC-Tae-124152	Triticum aestivum	30.23	5.00e-28	117.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence