iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022269

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02021943

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000010580.3	ENSCPOT00000010675.2	ENSCPOP00000009500.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	86.69	0.00e+00	1821.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	28.54	6.00e-37	150.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

VRRFKRKHLT AIECQQLAQS HLTVTQAFGQ RWTNRDLNHG LYPRPRTKRG NKGRVCQRYN 60
SEFILAGQQQ CTNDMAKSSS VGQDSCQDSE DDMIFPAENN CALPQGDGEA RLDSLRSALP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGAAGGT TTAAGCGGAA GCACCTTACA GCCATTGAGT GTCAGCAGTT GGCTCAGAGT 60
CATTTGACTG TGACCCAGGC CTTCGGTCAG AGATGGACAA ACAGGGATCT GAACCATGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	43.48	1.00e-03	39.30
IUUC-Aml-001396	Ailuropoda melanoleuca	86.60	0.00e+00	1830.00
IUUC-Atr-002826	Amborella trichopoda	44.26	2.00e-04	42.00
IUUC-Apl-003317	Anas platyrhynchos	46.60	0.00e+00	897.00
IUUC-Aca-004498	Anolis carolinensis	53.36	0.00e+00	919.00
IUUC-Ath-007293	Arabidopsis thaliana	39.06	4.00e-03	37.70
IUUC-Ani-009226	Aspergillus nidulans	35.58	1.00e-05	45.40
IUUC-Ate-010526	Aspergillus terreus	39.71	1.00e-04	42.40
IUUC-Ame-011808	Astyanax mexicanus	58.40	5.00e-135	474.00
IUUC-Bta-013250	Bos taurus	84.13	0.00e+00	1778.00
IUUC-Bol-015348	Brassica oleracea	37.10	4.00e-03	37.40
IUUC-Cja-019638	Callithrix jacchus	86.89	0.00e+00	1873.00
IUUC-Cfa-020195	Canis familiaris	88.07	0.00e+00	1751.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	40.28	3.00e-08	54.30
IUUC-Csa-024060	Chlorocebus sabaeus	87.85	0.00e+00	1670.00
IUUC-Cho-025003	Choloepus hoffmanni	82.83	0.00e+00	654.00
IUUC-Cin-025694	Ciona intestinalis	25.43	2.00e-23	103.00
IUUC-Dre-028083	Danio rerio	48.54	0.00e+00	810.00
IUUC-Dno-029203	Dasypus novemcinctus	82.90	0.00e+00	1672.00
IUUC-Dor-030477	Dipodomys ordii	93.35	0.00e+00	767.00
IUUC-Ete-032861	Echinops telfairi	84.13	0.00e+00	1759.00
IUUC-Eca-033205	Equus caballus	86.71	0.00e+00	1864.00
IUUC-Eeu-034784	Erinaceus europaeus	81.37	0.00e+00	1135.00
IUUC-Fca-035797	Felis catus	86.74	0.00e+00	1850.00
IUUC-Fso-038397	Fusarium solani	37.25	1.90e-02	35.00
IUUC-Gmo-038855	Gadus morhua	42.57	4.00e-109	389.00
IUUC-Gga-040326	Gallus gallus	49.09	0.00e+00	934.00
IUUC-Gac-042240	Gasterosteus aculeatus	44.12	0.00e+00	677.00
IUUC-Ggo-045050	Gorilla gorilla	82.60	0.00e+00	1714.00
IUUC-Hsa-046650	Homo sapiens	86.69	0.00e+00	1807.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	94.06	0.00e+00	756.00
IUUC-Lch-050231	Latimeria chalumnae	39.85	6.00e-152	531.00
IUUC-Loc-051884	Lepisosteus oculatus	46.99	0.00e+00	924.00
IUUC-Lma-053267	Leptosphaeria maculans	34.25	2.00e-03	38.10
IUUC-Laf-053843	Loxodonta africana	86.23	0.00e+00	1825.00
IUUC-Mcc-055570	Macaca mulatta	86.79	0.00e+00	1826.00
IUUC-Meu-056798	Macropus eugenii	62.37	2.00e-136	480.00
IUUC-Mtr-057915	Medicago truncatula	38.71	6.00e-04	40.40
IUUC-Mga-059648	Meleagris gallopavo	49.53	0.00e+00	887.00
IUUC-Mmr-060757	Microcebus murinus	84.48	0.00e+00	1753.00
IUUC-Mdo-061913	Monodelphis domestica	67.80	0.00e+00	1335.00
IUUC-Mmu-064337	Mus musculus	84.70	0.00e+00	1810.00
IUUC-Mpu-066483	Mustela putorius furo	84.88	0.00e+00	1833.00
IUUC-Mlu-068204	Myotis lucifugus	81.49	0.00e+00	1721.00
IUUC-Ncr-068735	Neurospora crassa	40.62	4.00e-04	40.80
IUUC-Nle-070053	Nomascus leucogenys	86.89	0.00e+00	1779.00
IUUC-Opr-070588	Ochotona princeps	82.41	0.00e+00	1707.00
IUUC-Ont-072655	Oreochromis niloticus	45.02	0.00e+00	708.00
IUUC-Oan-073351	Ornithorhynchus anatinus	60.04	0.00e+00	1238.00
IUUC-Ocu-074465	Oryctolagus cuniculus	86.30	0.00e+00	1745.00
IUUC-Oin-079176	Oryza indica	24.02	3.00e-04	40.00
IUUC-Olu-087831	Ostreococcus lucimarinus	32.37	2.00e-56	214.00
IUUC-Oga-089088	Otolemur garnettii	84.31	0.00e+00	1739.00
IUUC-Oar-089870	Ovis aries	83.84	0.00e+00	1750.00
IUUC-Ptr-090957	Pan troglodytes	85.88	0.00e+00	1782.00
IUUC-Pan-092632	Papio anubis	86.70	0.00e+00	1774.00
IUUC-Psi-093035	Pelodiscus sinensis	53.29	0.00e+00	1078.00
IUUC-Pno-094870	Phaeosphaeria nodorum	30.95	4.00e-03	37.40
IUUC-Ppa-095660	Physcomitrella patens	40.85	1.00e-04	42.40
IUUC-Pfo-096902	Poecilia formosa	42.95	0.00e+00	645.00
IUUC-Pab-098206	Pongo abelii	86.25	0.00e+00	1673.00
IUUC-Pop-098801	Populus trichocarpa	35.71	1.00e-03	39.30
IUUC-Pca-100238	Procavia capensis	80.31	0.00e+00	1682.00
IUUC-Ppe-101748	Prunus persica	37.10	6.00e-03	37.00
IUUC-Pva-103182	Pteropus vampyrus	83.92	0.00e+00	1736.00
IUUC-Pte-104033	Pyrenophora teres	35.94	6.00e-03	36.60
IUUC-Pyt-104599	Pyrenophora triticirepentis	35.94	5.00e-03	37.00
IUUC-Rno-105141	Rattus norvegicus	84.89	0.00e+00	1822.00
IUUC-Sce-106341	Saccharomyces cerevisiae	26.52	9.00e-04	38.90
IUUC-Sha-106827	Sarcophilus harrisii	65.20	0.00e+00	1383.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	27.84	1.00e-35	144.00
IUUC-Spo-108147	Schizosaccharomyces pombe	28.54	1.00e-36	148.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	25.81	5.00e-02	33.50
IUUC-Sly-111170	Solanum lycopersicum	39.06	2.10e-02	34.30
IUUC-Sre-115025	Sporisorium reilianum	31.80	1.00e-32	135.00
IUUC-Ssc-116188	Sus scrofa	87.83	0.00e+00	1183.00
IUUC-Tgu-116612	Taeniopygia guttata	54.87	8.00e-149	520.00
IUUC-Tsy-119560	Tarsius syrichta	81.85	1.00e-114	407.00
IUUC-Tni-120734	Tetraodon nigroviridis	44.17	0.00e+00	669.00
IUUC-Tca-121338	Theobroma cacao	37.10	1.40e-02	35.80
IUUC-Tre-122089	Trichoderma reesei	38.89	5.00e-04	39.70
IUUC-Tme-127009	Tuber melanosporum	34.94	6.00e-05	43.50
IUUC-Tbe-127431	Tupaia belangeri	85.04	0.00e+00	1544.00
IUUC-Ttr-128744	Tursiops truncatus	83.00	0.00e+00	1721.00
IUUC-Uma-129536	Ustilago maydis	32.89	8.00e-34	139.00
IUUC-Vpa-130123	Vicugna pacos	70.36	2.00e-93	337.00
IUUC-Vvi-131025	Vitis vinifera	38.71	3.00e-03	38.10
IUUC-Xtr-132902	Xenopus tropicalis	53.31	0.00e+00	1033.00
IUUC-Xma-133978	Xiphophorus maculatus	43.37	2.00e-140	493.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence