iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025633

Ensembl Protein ID

ENSCINP00000025987.2

UniProt Accession

F6TYU6; F6TYU6_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000014346.2	ENSCINT00000026233.2	ENSCINP00000025987.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.40e-26	88.8	49	84
UBD/Beta-Prp	1.40e-40	139.2	2	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
            ++++ f s+ ++l+++++Dg +++W++  g++lks
   Q: 49   AISSITFdSTgRRLITAGRDGAVRIWNYNNGHCLKS 84
           599****97779*********************986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..gh 93
           h++  tc ++  +  +++t s+ + +k+wd++tg+++ ++     ea++++++f+++g  l+t+++D+++++w++++g c+ +l+  + 
   Q: 2    HTEAATCCAYNSNFGHVITCSEGSVVKLWDFETGTFMFEFnkAHGEAAISSITFDSTGRRLITAGRDGAVRIWNYNNGHCLKSLEreNC 90
           78889999**888888********************999974455888*************************************4455 PP
   S: 94   edsvlslsfsp..sgdklvsGshdrtirvwdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            ++v+++s+ +  +++++++ ++d  i+++  e ++              + +gh++ + +v++    nll + s+D+ + +W++ +g 
   Q: 91   RKEVTDCSYVElnNNKYIIAVGWDHRINIFTDEMDEFHLIqrpqphwpddLRRGHTEDIVSVTFGR-PNLLGTVSYDGYIIVWNIISGH 178
           699********9777**************9666655544467*****9999*****9999999877.7*****************8888 PP
   S: 171  llrtl............tgghtdsvyslsfdsng......kelvsgsldgtvklwdlqtgecvrtlng..htdnvksvrfspnderlvs 239
            + +             + + +++v++l+f +n+       +l++g  dg  ++w++ +g+   ++++   ++  + + ++++ e+l++
   Q: 179  SMARIpypnidlckypeRVKEKGAVNKLAFLENRfldkmnASLIAGCSDGAAIVWNINHGKAHARWRAtcRKAGLSAMVVTSDCELLYV 267
           888888888999999996679********98888888889******************99997777653378999999999******** PP
   S: 240  gssDgsiriWdlrsgdllktlqlhnssvisva 271
           g   g ++iWd+ +  l   +q++  +v s  
   Q: 268  GDTLGFVSIWDIATYALRPLVQNPPYKVASWR 299
           *************9999888888776666655 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

SHTEAATCCA YNSNFGHVIT CSEGSVVKLW DFETGTFMFE FNKAHGEAAI SSITFDSTGR 60
RLITAGRDGA VRIWNYNNGH CLKSLERENC RKEVTDCSYV ELNNNKYIIA VGWDHRINIF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCACACTG AGGCTGCGAC ATGCTGTGCT TATAACTCAA ACTTTGGCCA CGTCATTACT 60
TGCTCTGAAG GATCGGTAAG TTAACCATGT ATTCTATGTG TTGTTGCTGC CAGGTGTATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001921	Ailuropoda melanoleuca	45.60	4.00e-93	333.00
IUUC-Ame-011582	Astyanax mexicanus	44.83	2.00e-97	348.00
IUUC-Bta-013034	Bos taurus	46.32	3.00e-92	330.00
IUUC-Csv-026326	Ciona savignyi	73.47	1.00e-176	611.00
IUUC-Dre-027573	Danio rerio	42.15	1.00e-98	353.00
IUUC-Dno-030073	Dasypus novemcinctus	42.33	3.00e-88	318.00
IUUC-Eca-033354	Equus caballus	44.94	3.00e-91	327.00
IUUC-Fca-036185	Felis catus	42.82	2.00e-83	301.00
IUUC-Gmo-039551	Gadus morhua	46.45	5.00e-46	177.00
IUUC-Gac-041482	Gasterosteus aculeatus	39.95	1.00e-84	305.00
IUUC-Itr-049019	Ictidomys tridecemlineatus	47.77	3.00e-100	357.00
IUUC-Lch-050242	Latimeria chalumnae	46.49	1.00e-104	372.00
IUUC-Loc-052710	Lepisosteus oculatus	43.65	1.00e-99	355.00
IUUC-Mdo-062347	Monodelphis domestica	44.76	4.00e-101	360.00
IUUC-Mmu-063878	Mus musculus	46.23	2.00e-101	362.00
IUUC-Mpu-065721	Mustela putorius furo	40.87	2.00e-38	150.00
IUUC-Ont-071688	Oreochromis niloticus	38.12	7.00e-78	283.00
IUUC-Oan-072752	Ornithorhynchus anatinus	42.26	7.00e-79	286.00
IUUC-Ocu-074780	Oryctolagus cuniculus	37.01	4.00e-47	179.00
IUUC-Ola-086449	Oryzias latipes	36.94	4.00e-69	254.00
IUUC-Psi-094057	Pelodiscus sinensis	36.36	1.00e-33	135.00
IUUC-Pma-094599	Petromyzon marinus	46.20	4.00e-99	353.00
IUUC-Pfo-096408	Poecilia formosa	39.05	5.00e-85	307.00
IUUC-Rno-105331	Rattus norvegicus	41.05	5.00e-83	300.00
IUUC-Sha-106832	Sarcophilus harrisii	48.03	6.00e-102	363.00
IUUC-Ssc-116310	Sus scrofa	45.31	2.00e-91	328.00
IUUC-Tru-117666	Takifugu rubripes	37.83	2.00e-75	275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence