iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012988

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02003438

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000023393.4	ENSBTAT00000031852.3	ENSBTAP00000031798.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.50e-13	50.8	305	350

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           + C+ C++gge    l++C+ C ++fH aCl ++  +e p+ + w C++C +
   Q: 305  DECAACRDGGE----LLCCDGCPRAFHLACLTPP-LSEIPSGT-WRCSNCVQ 350
           5699*******....*******************.*******6.******75 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAGETRAGGD AALRRLLRLH RTEIAVAVDS AFPLLHALAD HDVVPEEKFQ ETLRLKEKEG 60
CPQAFHALLS WLLTQDTGAI LDFWRVLFKD YNLERYARLQ SILDTFPKDV DLSQPRKGRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAGGAGGCC GGAGGAAGCT GTCAGGACTC CCTCTCCCCG AGCAGGTGAG CCCGCCCAGG 60
TGTCCCCGGC GCAGGCGGAG CTCAAGGACC AGGAGGCAGA CACGGCCCGG ACACCCCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0006955--P:immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	78.43	0.00e+00	712.00
IUUC-Aca-004543	Anolis carolinensis	66.13	5.00e-24	102.00
IUUC-Cja-019486	Callithrix jacchus	67.26	5.00e-98	350.00
IUUC-Cfa-021069	Canis familiaris	78.32	0.00e+00	673.00
IUUC-Cpo-021649	Cavia porcellus	69.01	7.00e-164	570.00
IUUC-Csa-023960	Chlorocebus sabaeus	75.55	1.00e-176	612.00
IUUC-Cne-026966	Cryptococcus neoformans	56.86	9.00e-12	65.10
IUUC-Dre-028583	Danio rerio	38.37	4.00e-58	219.00
IUUC-Dno-029869	Dasypus novemcinctus	65.97	4.00e-141	494.00
IUUC-Dor-030263	Dipodomys ordii	86.17	6.00e-46	177.00
IUUC-Dse-031258	Dothistroma septosporum	41.79	3.00e-10	61.20
IUUC-Ete-032778	Echinops telfairi	90.00	5.00e-48	185.00
IUUC-Eca-034328	Equus caballus	77.56	0.00e+00	682.00
IUUC-Fca-035400	Felis catus	73.17	0.00e+00	661.00
IUUC-Fal-036644	Ficedula albicollis	42.22	9.00e-83	300.00
IUUC-Fox-038014	Fusarium oxysporum	40.43	1.00e-08	55.80
IUUC-Ggo-045250	Gorilla gorilla	75.32	2.00e-179	622.00
IUUC-Hsa-046603	Homo sapiens	75.50	1.00e-179	622.00
IUUC-Hvu-047073	Hordeum vulgare	58.70	2.00e-13	71.60
IUUC-Itr-048977	Ictidomys tridecemlineatus	70.57	1.00e-167	582.00
IUUC-Lch-050310	Latimeria chalumnae	42.41	1.00e-98	353.00
IUUC-Loc-052508	Lepisosteus oculatus	39.21	3.00e-94	338.00
IUUC-Lma-053053	Leptosphaeria maculans	29.22	8.00e-17	82.80
IUUC-Laf-054028	Loxodonta africana	69.72	3.00e-171	595.00
IUUC-Mcc-054935	Macaca mulatta	74.27	0.00e+00	647.00
IUUC-Mga-059318	Meleagris gallopavo	42.07	2.00e-51	196.00
IUUC-Mmr-061557	Microcebus murinus	60.55	2.00e-143	502.00
IUUC-Mdo-062475	Monodelphis domestica	49.73	3.00e-126	445.00
IUUC-Mmu-063994	Mus musculus	71.56	0.00e+00	726.00
IUUC-Mac-065614	Musa acuminata	42.42	7.00e-12	66.20
IUUC-Mpu-066347	Mustela putorius furo	77.25	0.00e+00	744.00
IUUC-Mlu-068239	Myotis lucifugus	62.72	6.00e-98	350.00
IUUC-Nle-069544	Nomascus leucogenys	76.19	6.00e-25	107.00
IUUC-Opr-071199	Ochotona princeps	72.69	9.00e-72	264.00
IUUC-Ont-072571	Oreochromis niloticus	32.84	3.00e-35	142.00
IUUC-Oan-073739	Ornithorhynchus anatinus	53.75	1.00e-144	506.00
IUUC-Ola-086528	Oryzias latipes	34.55	9.00e-41	161.00
IUUC-Oga-088353	Otolemur garnettii	74.40	0.00e+00	714.00
IUUC-Oar-090065	Ovis aries	95.30	0.00e+00	670.00
IUUC-Ptr-091347	Pan troglodytes	72.91	8.00e-174	603.00
IUUC-Pan-092423	Papio anubis	73.70	0.00e+00	646.00
IUUC-Psi-093798	Pelodiscus sinensis	51.49	4.00e-128	451.00
IUUC-Pfo-096145	Poecilia formosa	76.09	1.00e-19	91.30
IUUC-Pab-098369	Pongo abelii	79.76	2.00e-128	452.00
IUUC-Pca-100537	Procavia capensis	70.40	0.00e+00	634.00
IUUC-Ppe-101215	Prunus persica	60.42	4.00e-14	73.90
IUUC-Pva-102639	Pteropus vampyrus	78.97	0.00e+00	671.00
IUUC-Pte-104185	Pyrenophora teres	27.10	2.00e-15	79.00
IUUC-Pyt-104775	Pyrenophora triticirepentis	27.57	7.00e-16	79.70
IUUC-Rno-105285	Rattus norvegicus	71.86	0.00e+00	737.00
IUUC-Sha-107159	Sarcophilus harrisii	49.20	2.00e-128	452.00
IUUC-Sja-107964	Schizosaccharomyces japonicus	29.91	2.00e-11	63.90
IUUC-Sit-110355	Setaria italica	54.17	4.00e-12	67.80
IUUC-Sbi-113930	Sorghum bicolor	54.17	4.00e-12	67.80
IUUC-Ssc-115773	Sus scrofa	78.13	0.00e+00	721.00
IUUC-Tgu-116922	Taeniopygia guttata	50.15	7.00e-72	263.00
IUUC-Tru-118263	Takifugu rubripes	30.70	1.00e-55	211.00
IUUC-Tsy-119270	Tarsius syrichta	68.68	1.00e-90	327.00
IUUC-Tni-120138	Tetraodon nigroviridis	30.81	2.00e-61	230.00
IUUC-Tca-121757	Theobroma cacao	54.72	9.00e-14	73.20
IUUC-Tae-124715	Triticum aestivum	58.70	2.00e-13	71.60
IUUC-Tur-126422	Triticum urartu	55.32	8.00e-12	67.00
IUUC-Tme-127204	Tuber melanosporum	54.17	1.00e-13	72.40
IUUC-Tbe-128077	Tupaia belangeri	70.02	0.00e+00	687.00
IUUC-Ttr-128781	Tursiops truncatus	88.77	5.00e-90	325.00
IUUC-Xma-133054	Xiphophorus maculatus	30.30	2.00e-58	219.00
IUUC-Yli-134436	Yarrowia lipolytica	25.00	6.00e-12	65.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence