iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011262

Ensembl Protein ID

ENSAMXP00000008390.1

UniProt Accession

W5KLC8; W5KLC8_ASTMX

Genbank Protein ID

ENSAMXP00000008390

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

APWO01002931

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000008166.1	ENSAMXT00000008390.1	ENSAMXP00000008390.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.80e-09	36.2	222	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 222  TYC-LCEQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCR 268
           69*.*******99..******9**99***********...999997.******8 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MLNTASWDPL HVANYVAEYL DLVESLPFDL QRNVSLMREI DSKYQEILKE LDEAYQKHSQ 60
EEDPIQRRRL LHCIQRALIR SQELGDEKIQ LASQMVELVE NRSRQVDGFA ELLEAQNEPH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAACA CTGCCAGCTG GGACCCGCTG CACGTTGCCA ACTATGTGGC TGAATATCTG 60
GACTTGGTTG AATCGCTGCC GTTCGACCTA CAAAGAAACG TGTCCCTCAT GAGAGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	66.90	2.00e-93	335.00
IUUC-Apl-003910	Anas platyrhynchos	65.40	5.00e-91	327.00
IUUC-Aca-004874	Anolis carolinensis	66.67	2.00e-91	328.00
IUUC-Bta-013507	Bos taurus	66.53	2.00e-67	248.00
IUUC-Cja-018925	Callithrix jacchus	69.07	2.00e-92	332.00
IUUC-Cfa-020947	Canis familiaris	67.59	2.00e-93	335.00
IUUC-Cpo-022286	Cavia porcellus	65.18	2.00e-71	262.00
IUUC-Cho-024577	Choloepus hoffmanni	66.39	4.00e-72	264.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	1.00e-16	80.50
IUUC-Dno-029834	Dasypus novemcinctus	67.24	2.00e-93	335.00
IUUC-Dor-030315	Dipodomys ordii	69.92	2.00e-78	286.00
IUUC-Eca-034244	Equus caballus	65.71	6.00e-72	263.00
IUUC-Fca-035391	Felis catus	64.44	1.00e-77	282.00
IUUC-Fal-036838	Ficedula albicollis	65.86	6.00e-92	330.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	1.00e-19	90.90
IUUC-Gmo-038557	Gadus morhua	68.91	6.00e-42	164.00
IUUC-Gga-040619	Gallus gallus	66.21	5.00e-92	330.00
IUUC-Gac-041996	Gasterosteus aculeatus	59.93	5.00e-89	320.00
IUUC-Ggo-045481	Gorilla gorilla	67.74	4.00e-72	265.00
IUUC-Hsa-046170	Homo sapiens	67.74	2.00e-72	265.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	66.12	4.00e-72	264.00
IUUC-Lch-050397	Latimeria chalumnae	66.21	1.00e-93	335.00
IUUC-Loc-052038	Lepisosteus oculatus	73.13	6.00e-94	336.00
IUUC-Laf-054126	Loxodonta africana	66.21	5.00e-92	330.00
IUUC-Meu-056248	Macropus eugenii	65.18	4.00e-72	264.00
IUUC-Mga-059217	Meleagris gallopavo	65.16	1.00e-70	259.00
IUUC-Mmr-061581	Microcebus murinus	66.93	2.00e-77	281.00
IUUC-Mdo-062452	Monodelphis domestica	66.55	5.00e-93	333.00
IUUC-Mmu-063412	Mus musculus	66.55	2.00e-92	332.00
IUUC-Mpu-066479	Mustela putorius furo	66.53	1.00e-73	269.00
IUUC-Mlu-067586	Myotis lucifugus	61.43	5.00e-85	307.00
IUUC-Nle-069122	Nomascus leucogenys	69.42	6.00e-93	333.00
IUUC-Opr-070835	Ochotona princeps	92.50	2.00e-45	175.00
IUUC-Ont-071606	Oreochromis niloticus	55.10	2.00e-85	308.00
IUUC-Oan-073023	Ornithorhynchus anatinus	67.24	6.00e-93	333.00
IUUC-Ocu-073779	Oryctolagus cuniculus	65.71	5.00e-71	260.00
IUUC-Ola-086891	Oryzias latipes	64.60	2.00e-92	332.00
IUUC-Olu-087851	Ostreococcus lucimarinus	69.23	1.00e-19	89.70
IUUC-Oga-087954	Otolemur garnettii	66.21	2.00e-91	328.00
IUUC-Oar-090006	Ovis aries	66.55	4.00e-91	327.00
IUUC-Ptr-090589	Pan troglodytes	69.07	2.00e-92	332.00
IUUC-Psi-093266	Pelodiscus sinensis	66.89	4.00e-92	330.00
IUUC-Pma-094265	Petromyzon marinus	72.60	3.00e-32	130.00
IUUC-Pfo-097531	Poecilia formosa	63.11	2.00e-90	325.00
IUUC-Pab-098253	Pongo abelii	68.73	4.00e-92	330.00
IUUC-Pva-102753	Pteropus vampyrus	59.41	7.00e-62	231.00
IUUC-Rno-105964	Rattus norvegicus	66.12	8.00e-71	259.00
IUUC-Sha-107270	Sarcophilus harrisii	66.90	5.00e-93	333.00
IUUC-Tgu-116822	Taeniopygia guttata	66.21	1.00e-91	329.00
IUUC-Tru-118262	Takifugu rubripes	57.60	7.00e-75	273.00
IUUC-Tni-119980	Tetraodon nigroviridis	53.57	4.00e-77	281.00
IUUC-Tvi-122341	Trichoderma virens	60.71	1.00e-15	75.10
IUUC-Ttr-128672	Tursiops truncatus	66.26	7.00e-73	266.00
IUUC-Xtr-132200	Xenopus tropicalis	63.45	1.00e-85	309.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence