iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073005

UUCD1 version

UUC-OrA-00781

Ensembl Protein ID

ENSOANP00000026949.1

UniProt Accession

F7EYU9; F7EYU9_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2U

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000021175.2	ENSOANT00000030749.2	ENSOANP00000026949.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	8.40e-28	97.1	9	139

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeee 90
           l++e+ +l++++  gi+  pv + d+  w+++i G +d+ +e g+F l+i+fpe+Y+  PP+v+f t  fhP   ++G+ C+++l+++e
   Q: 9    LEREYLQLKDSSLFGIV-APVGD-DMLMWRAEIQGLKDSLWE-GAFLLSIKFPEEYNQVPPNVTFNTIPFHPVDMHSGRPCIDFLDNSE 94
           679999**999999995.56666.6****************9.58***************************98899************ PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           +W   +s++s+ll+iq+ll++p  e+++n+ea  +++kn ++y+++v
   Q: 95   EWDERYSLSSILLAIQALLSNPVLENAVNVEA--MMRKNMSSYRQMV 139
           *****************************999..7999******998 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MHGRAYWLLE REYLQLKDSS LFGIVAPVGD DMLMWRAEIQ GLKDSLWEGA FLLSIKFPEE 60
YNQVPPNVTF NTIPFHPVDM HSGRPCIDFL DNSEEWDERY SLSSILLAIQ ALLSNPVLEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCATCAGA CTTCCCTCTT TTCCTCCCCG TTGCTCGGCA ACCGGCGCCC CCTCCCTGCC 60
TGGAAACCAG GACTGCCGGC GGAACATCAG GTCCTAGGCG CTGCGTTCAT CCCTATCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002211	Ailuropoda melanoleuca	47.29	4.00e-44	170.00
IUUC-Aca-004682	Anolis carolinensis	51.05	2.00e-59	221.00
IUUC-Bta-013054	Bos taurus	47.49	9.00e-56	209.00
IUUC-Cja-018784	Callithrix jacchus	45.41	3.00e-50	191.00
IUUC-Cfa-020877	Canis familiaris	50.00	8.00e-55	205.00
IUUC-Cpo-022462	Cavia porcellus	50.30	4.00e-41	159.00
IUUC-Csa-023486	Chlorocebus sabaeus	49.34	2.00e-56	211.00
IUUC-Cho-024685	Choloepus hoffmanni	34.84	7.00e-20	90.50
IUUC-Dno-029061	Dasypus novemcinctus	47.71	9.00e-49	186.00
IUUC-Ete-032233	Echinops telfairi	37.27	7.00e-38	149.00
IUUC-Eca-033400	Equus caballus	55.86	6.00e-31	125.00
IUUC-Fca-035778	Felis catus	51.10	7.00e-60	223.00
IUUC-Ggo-044718	Gorilla gorilla	51.10	2.00e-57	215.00
IUUC-Hsa-046798	Homo sapiens	50.66	4.00e-57	214.00
IUUC-Lch-050337	Latimeria chalumnae	53.70	2.00e-58	218.00
IUUC-Loc-051819	Lepisosteus oculatus	55.05	3.00e-54	204.00
IUUC-Laf-054536	Loxodonta africana	48.18	8.00e-55	206.00
IUUC-Mcc-055028	Macaca mulatta	48.46	2.00e-54	205.00
IUUC-Mmr-061623	Microcebus murinus	42.73	3.00e-43	167.00
IUUC-Mdo-062614	Monodelphis domestica	41.35	7.00e-40	156.00
IUUC-Mmu-063194	Mus musculus	46.54	3.00e-46	178.00
IUUC-Mpu-066467	Mustela putorius furo	48.02	4.00e-49	187.00
IUUC-Mlu-067976	Myotis lucifugus	46.46	3.00e-46	177.00
IUUC-Nle-069407	Nomascus leucogenys	46.90	2.00e-51	195.00
IUUC-Opr-070526	Ochotona princeps	44.12	5.00e-30	123.00
IUUC-Ocu-074953	Oryctolagus cuniculus	47.96	2.00e-50	191.00
IUUC-Oga-089061	Otolemur garnettii	48.46	3.00e-56	211.00
IUUC-Oar-090147	Ovis aries	46.33	6.00e-52	197.00
IUUC-Ptr-090873	Pan troglodytes	51.14	7.00e-57	213.00
IUUC-Pan-091873	Papio anubis	48.90	1.00e-55	208.00
IUUC-Psi-093780	Pelodiscus sinensis	54.04	1.00e-37	149.00
IUUC-Pab-098662	Pongo abelii	50.66	7.00e-58	216.00
IUUC-Pca-100167	Procavia capensis	37.33	1.00e-34	139.00
IUUC-Pva-102119	Pteropus vampyrus	43.81	4.00e-15	74.70
IUUC-Rno-105522	Rattus norvegicus	41.20	5.00e-41	160.00
IUUC-Sar-113070	Sorex araneus	42.27	3.00e-36	143.00
IUUC-Ssc-115890	Sus scrofa	47.51	2.00e-58	218.00
IUUC-Tsy-119341	Tarsius syrichta	44.95	4.00e-43	167.00
IUUC-Tbe-127433	Tupaia belangeri	37.72	6.00e-28	117.00
IUUC-Ttr-128614	Tursiops truncatus	42.66	2.00e-41	161.00
IUUC-Vpa-130777	Vicugna pacos	47.74	1.00e-48	186.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence