iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.30e-22	77.8	1099	1170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
            p+ef++p++ +lM+dPv lpsG  +drs I ++l ++ + +P++rq lte++l P  +l++ iqaw+ e++s
   Q: 1099 APDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPT-DPFNRQMLTESMLEPVPELKEQIQAWMREKQS 1170
           79**********************************9998.****************************9986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEELSADEIR RRRLARLAGG QTSQPTTPLT SPQRENPPGP PIAASVPGPS QSLGLNVHNT 60
TPATSPIGAA GVAHRSQSSE GVSSLSSSPS NSLETQSQSL SRSQSMDIDG VSCEKSMSQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGAGGGG GTGGGGCAGG GGGCGGGGAC AGGATGCAAG CGAAGAGGAA ATCAGCGGCG 60
CGACGCCTTC TGCTTATTGG CTGGTGAGTC CGGGAGCCAG AAGCCCCGCC TCCCCAGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0051117--F:ATPase binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008626--P:granzyme-mediated apoptotic signaling pathway
GO:0031175--P:neuron projection development
GO:0051865--P:protein autoubiquitination
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0009411--P:response to UV
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0003222--P:ventricular trabecula myocardium morphogenesis

KEGG

rno:298652

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000585	Aegilops tauschii	32.83	2.00e-98	353.00
IUUC-Aml-002396	Ailuropoda melanoleuca	97.88	0.00e+00	1721.00
IUUC-Atr-002479	Amborella trichopoda	31.90	5.00e-102	365.00
IUUC-Apl-003747	Anas platyrhynchos	93.60	0.00e+00	1682.00
IUUC-Aca-004866	Anolis carolinensis	92.58	0.00e+00	1658.00
IUUC-Aly-006300	Arabidopsis lyrata	30.65	2.00e-90	327.00
IUUC-Ath-006962	Arabidopsis thaliana	30.74	7.00e-88	318.00
IUUC-Ago-007880	Ashbya gossypii	29.83	3.00e-80	293.00
IUUC-Acl-008289	Aspergillus clavatus	30.52	2.00e-103	370.00
IUUC-Afl-008711	Aspergillus flavus	31.15	1.00e-107	384.00
IUUC-Afu-008766	Aspergillus fumigatus	30.77	2.00e-107	384.00
IUUC-Ani-009126	Aspergillus nidulans	31.11	2.00e-105	377.00
IUUC-Ang-009837	Aspergillus niger	30.67	2.00e-103	370.00
IUUC-Aor-009919	Aspergillus oryzae	30.73	5.00e-104	372.00
IUUC-Ate-010300	Aspergillus terreus	31.74	7.00e-110	392.00
IUUC-Ame-011355	Astyanax mexicanus	84.61	0.00e+00	1577.00
IUUC-Bgr-011995	Blumeria graminis	30.22	2.00e-102	367.00
IUUC-Bta-013056	Bos taurus	97.99	0.00e+00	1722.00
IUUC-Bci-013605	Botrytis cinerea	28.83	1.00e-90	328.00
IUUC-Bdi-015032	Brachypodium distachyon	30.45	1.00e-92	334.00
IUUC-Bol-016124	Brassica oleracea	30.87	1.00e-97	351.00
IUUC-Bra-017426	Brassica rapa	30.72	8.00e-98	352.00
IUUC-Cel-018606	Caenorhabditis elegans	30.73	9.00e-100	358.00
IUUC-Cja-018872	Callithrix jacchus	97.76	0.00e+00	1723.00
IUUC-Cfa-020045	Canis familiaris	97.77	0.00e+00	1719.00
IUUC-Cpo-022309	Cavia porcellus	96.34	0.00e+00	2036.00
IUUC-Cre-022726	Chlamydomonas reinhardtii	29.65	1.00e-49	190.00
IUUC-Csa-024003	Chlorocebus sabaeus	96.52	0.00e+00	1091.00
IUUC-Cho-025092	Choloepus hoffmanni	97.70	0.00e+00	683.00
IUUC-Cin-025533	Ciona intestinalis	47.28	0.00e+00	838.00
IUUC-Csv-026081	Ciona savignyi	63.98	5.00e-60	223.00
IUUC-Cgl-026710	Colletotrichum gloeosporioides	31.55	4.00e-107	382.00
IUUC-Cne-027098	Cryptococcus neoformans	29.67	5.00e-108	386.00
IUUC-Cme-027352	Cyanidioschyzon merolae	32.25	7.00e-87	315.00
IUUC-Dre-027979	Danio rerio	83.80	0.00e+00	1516.00
IUUC-Dno-029282	Dasypus novemcinctus	97.99	0.00e+00	1719.00
IUUC-Dor-030904	Dipodomys ordii	78.89	0.00e+00	743.00
IUUC-Dse-031393	Dothistroma septosporum	29.74	9.00e-101	361.00
IUUC-Dme-031666	Drosophila melanogaster	39.08	0.00e+00	691.00
IUUC-Ete-032519	Echinops telfairi	98.16	1.00e-178	620.00
IUUC-Eca-033778	Equus caballus	97.21	0.00e+00	1707.00
IUUC-Eeu-035315	Erinaceus europaeus	89.16	0.00e+00	880.00
IUUC-Fca-035658	Felis catus	97.54	0.00e+00	1711.00
IUUC-Fal-037638	Ficedula albicollis	92.91	0.00e+00	1674.00
IUUC-Fox-037909	Fusarium oxysporum	29.61	5.00e-98	352.00
IUUC-Fso-038406	Fusarium solani	29.92	5.00e-97	350.00
IUUC-Gmo-039379	Gadus morhua	79.44	0.00e+00	1745.00
IUUC-Ggr-039851	Gaeumannomyces graminis	31.94	1.00e-106	381.00
IUUC-Gga-041136	Gallus gallus	93.58	0.00e+00	1686.00
IUUC-Gac-041910	Gasterosteus aculeatus	80.12	0.00e+00	1759.00
IUUC-Gma-043995	Glycine max	29.00	6.00e-96	345.00
IUUC-Ggo-045354	Gorilla gorilla	88.93	0.00e+00	1834.00
IUUC-Hsa-046880	Homo sapiens	97.87	0.00e+00	1751.00
IUUC-Hvu-047157	Hordeum vulgare	32.87	1.00e-93	337.00
IUUC-Itr-048213	Ictidomys tridecemlineatus	97.60	0.00e+00	635.00
IUUC-Kpa-049211	Komagataella pastoris	28.34	3.00e-78	286.00
IUUC-Lch-050534	Latimeria chalumnae	87.88	0.00e+00	1596.00
IUUC-Lpe-051022	Leersia perrieri	31.02	4.00e-94	339.00
IUUC-Loc-052622	Lepisosteus oculatus	85.76	0.00e+00	1547.00
IUUC-Lma-053241	Leptosphaeria maculans	30.29	7.00e-100	358.00
IUUC-Laf-053646	Loxodonta africana	97.54	0.00e+00	1721.00
IUUC-Mcc-055588	Macaca mulatta	97.99	0.00e+00	1723.00
IUUC-Meu-055999	Macropus eugenii	78.85	0.00e+00	1326.00
IUUC-Mor-057064	Magnaporthe oryzae	31.02	5.00e-106	379.00
IUUC-Mpo-057452	Magnaporthe poae	31.87	4.00e-107	383.00
IUUC-Mtr-058016	Medicago truncatula	29.67	2.00e-102	367.00
IUUC-Mla-058887	Melampsora laricipopulina	32.93	4.00e-110	392.00
IUUC-Mga-059497	Meleagris gallopavo	93.36	0.00e+00	1678.00
IUUC-Mvi-060343	Microbotryum violaceum	34.12	4.00e-114	406.00
IUUC-Mmr-061173	Microcebus murinus	89.16	0.00e+00	1480.00
IUUC-Mdo-062102	Monodelphis domestica	94.37	0.00e+00	2044.00
IUUC-Mmu-063223	Mus musculus	98.81	0.00e+00	2103.00
IUUC-Mac-065531	Musa acuminata	30.90	3.00e-98	353.00
IUUC-Mpu-066624	Mustela putorius furo	65.90	0.00e+00	1040.00
IUUC-Mlu-068018	Myotis lucifugus	96.65	0.00e+00	1699.00
IUUC-Nfi-068590	Neosartorya fischeri	31.30	9.00e-109	388.00
IUUC-Ncr-068901	Neurospora crassa	31.48	5.00e-105	376.00
IUUC-Nle-069605	Nomascus leucogenys	96.76	0.00e+00	1691.00
IUUC-Opr-071011	Ochotona princeps	83.37	0.00e+00	830.00
IUUC-Ont-072304	Oreochromis niloticus	84.06	0.00e+00	1482.00
IUUC-Oan-073410	Ornithorhynchus anatinus	96.50	0.00e+00	1100.00
IUUC-Ocu-074910	Oryctolagus cuniculus	97.30	0.00e+00	1716.00
IUUC-Oba-075073	Oryza barthii	30.99	3.00e-100	359.00
IUUC-Obr-076452	Oryza brachyantha	31.32	3.00e-98	353.00
IUUC-Ogl-077141	Oryza glaberrima	30.99	4.00e-100	359.00
IUUC-Ogu-078116	Oryza glumaepatula	30.99	4.00e-100	359.00
IUUC-Oin-079066	Oryza indica	31.11	2.00e-100	360.00
IUUC-Olo-080253	Oryza longistaminata	29.31	6.00e-87	315.00
IUUC-Ome-081263	Oryza meridionalis	30.87	2.00e-99	357.00
IUUC-Oni-082019	Oryza nivara	31.32	2.00e-100	360.00
IUUC-Opu-083558	Oryza punctata	31.23	6.00e-101	362.00
IUUC-Oru-085002	Oryza rufipogon	31.20	6.00e-100	358.00
IUUC-Osa-085980	Oryza sativa	31.11	2.00e-100	360.00
IUUC-Ola-086323	Oryzias latipes	80.90	0.00e+00	1431.00
IUUC-Olu-087901	Ostreococcus lucimarinus	30.06	3.00e-100	359.00
IUUC-Oga-087969	Otolemur garnettii	93.97	0.00e+00	1598.00
IUUC-Oar-090020	Ovis aries	95.59	0.00e+00	1644.00
IUUC-Ptr-091589	Pan troglodytes	97.87	0.00e+00	1750.00
IUUC-Pan-091718	Papio anubis	98.40	0.00e+00	855.00
IUUC-Psi-093013	Pelodiscus sinensis	93.06	0.00e+00	1689.00
IUUC-Pma-094627	Petromyzon marinus	74.36	2.00e-180	625.00
IUUC-Pno-094840	Phaeosphaeria nodorum	30.16	2.00e-106	380.00
IUUC-Ppa-095989	Physcomitrella patens	29.38	5.00e-100	359.00
IUUC-Pfo-096436	Poecilia formosa	85.19	0.00e+00	1535.00
IUUC-Pab-098275	Pongo abelii	86.31	0.00e+00	1749.00
IUUC-Pop-098797	Populus trichocarpa	30.39	7.00e-103	368.00
IUUC-Pca-100478	Procavia capensis	72.14	0.00e+00	669.00
IUUC-Ppe-101230	Prunus persica	30.92	5.00e-106	379.00
IUUC-Pva-102459	Pteropus vampyrus	92.73	0.00e+00	1603.00
IUUC-Pgr-103485	Puccinia graminis	33.05	6.00e-110	392.00
IUUC-Ptt-104001	Puccinia triticina	41.77	6.00e-45	176.00
IUUC-Pte-104084	Pyrenophora teres	32.08	6.00e-114	405.00
IUUC-Pyt-104484	Pyrenophora triticirepentis	31.92	4.00e-113	402.00
IUUC-Sce-106135	Saccharomyces cerevisiae	29.36	3.00e-79	290.00
IUUC-Sha-106760	Sarcophilus harrisii	94.61	0.00e+00	1979.00
IUUC-Sja-107698	Schizosaccharomyces japonicus	32.48	3.00e-117	416.00
IUUC-Spo-108076	Schizosaccharomyces pombe	32.60	5.00e-106	379.00
IUUC-Ssl-108624	Sclerotinia sclerotiorum	29.63	3.00e-102	367.00
IUUC-Smo-108769	Selaginella moellendorffii	29.30	1.00e-93	338.00
IUUC-Sit-109949	Setaria italica	31.34	6.00e-96	345.00
IUUC-Sly-110973	Solanum lycopersicum	31.09	4.00e-85	309.00
IUUC-Stu-112372	Solanum tuberosum	29.74	1.00e-103	371.00
IUUC-Sar-113469	Sorex araneus	89.24	0.00e+00	1029.00
IUUC-Sbi-113828	Sorghum bicolor	30.89	4.00e-99	356.00
IUUC-Sre-114967	Sporisorium reilianum	32.90	9.00e-105	375.00
IUUC-Ssc-115655	Sus scrofa	96.53	0.00e+00	1098.00
IUUC-Tgu-117290	Taeniopygia guttata	93.04	0.00e+00	1632.00
IUUC-Tru-118193	Takifugu rubripes	84.23	0.00e+00	1520.00
IUUC-Tsy-118926	Tarsius syrichta	97.32	0.00e+00	1712.00
IUUC-Tni-120862	Tetraodon nigroviridis	82.33	0.00e+00	1750.00
IUUC-Tca-121096	Theobroma cacao	31.51	7.00e-104	372.00
IUUC-Tre-122104	Trichoderma reesei	30.69	4.00e-99	357.00
IUUC-Tvi-122345	Trichoderma virens	30.76	6.00e-103	369.00
IUUC-Tae-124839	Triticum aestivum	32.83	1.00e-98	354.00
IUUC-Tur-126056	Triticum urartu	32.83	1.00e-98	354.00
IUUC-Tme-127074	Tuber melanosporum	32.73	2.00e-102	367.00
IUUC-Tbe-127533	Tupaia belangeri	93.74	0.00e+00	1637.00
IUUC-Ttr-128757	Tursiops truncatus	95.87	0.00e+00	1683.00
IUUC-Uma-129550	Ustilago maydis	32.95	3.00e-106	380.00
IUUC-Vda-129901	Verticillium dahliae	30.96	7.00e-103	369.00
IUUC-Vpa-130636	Vicugna pacos	96.22	0.00e+00	1025.00
IUUC-Vvi-130891	Vitis vinifera	31.01	3.00e-103	370.00
IUUC-Xtr-132364	Xenopus tropicalis	87.49	0.00e+00	1571.00
IUUC-Xma-133772	Xiphophorus maculatus	85.07	0.00e+00	1533.00
IUUC-Yli-134506	Yarrowia lipolytica	30.97	5.00e-85	309.00
IUUC-Zma-135695	Zea mays	31.19	8.00e-92	332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence