iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004637

UUCD1 version

UUC-AnC-01013

Ensembl Protein ID

ENSACAP00000007692.3

UniProt Accession

G1KH47; G1KH47_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007833.3	ENSACAT00000007857.3	ENSACAP00000007692.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-82	276.9	82	774

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel.......w..... 61
           +Gl+NlgNtCY+NS+LQ+L+++p ++  +++      kkke+l++e +k   g          el++sl++l+ ++       +     
   Q: 82   VGLNNLGNTCYLNSILQVLYFCPGFKTGVKQlfniisKKKESLKDELDK---GtikedslagyELVCSLHSLIISVeqlqasfLlspdk 167
           6******************************888776555666555332...1355778888988888888888884444443244454 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk..........eknkpkeeeeeedkselsde........... 129
           + ++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++ +++           ++ +pk +++++++se+  +           
   Q: 168  YADELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGHIQGTCQLlkeelkhkslQAPTPKLRKKSSQNSES--Ngileqddnvld 254
           66666*****************************************55666677774433333333333333333..366999999*** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 255  dhvkkdcedknkgsvkrksdieggnekkksrvskeknggeenlrqtrskrkaleekrenhpeaatdemkihieiakpsnkksrlrlnwl 343
           ***************************************************************************************** PP
   S: 130  ..................................................................aeekkkkknkslisdlFqgqlks 152
                                                                             ++ kk+    +l+++lFqgql  
   Q: 344  ksssnqpsilskfcslgklttnlglkdpikeiencefpgmsvkceksnqpmedsspkestaekgteKPFKKELADFDLVERLFQGQLVL 432
           *******************************************************999998877766666666777************* PP
   S: 153  qikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklP 227
           +++clec+  ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+ky+ce+c++++eae++l ++k+P
   Q: 433  RTRCLECECFTERREDFQDISVPVQKDELSKVEdnseispepkmevkTLKWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMP 521
           ****************************99999******************************************************** PP
   S: 228  evLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn......... 301
           ev+++hLk+f     +f+++++  +kin+ +++pl+L+l+ + ++p      +++Y L+avv+HsG ++ssGHY+a vk          
   Q: 522  EVITIHLKCFaasglEFDCYGGL-SKINTPLQTPLKLSLDDWSINPA-----NEIYGLFAVVMHSGiTISSGHYTASVKItdldsleld 604
           *******************9555.6********************88.....789********************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 605  kdnfildalgkicpeplneqearavtedyddgevsfrvggnaqpnkglnkknteavgllggqksksscdlpinkashsekmanmtieak 693
           ***************************************************************************************** PP
   S: 302  .......................................ekgkWllfdDskVtevkeeevleetg......staYvlfYkr 337
                                                   +gkWllfdDs+V++++e+++l+  +      st+Y+lfYk+
   Q: 694  saecshakqivefkhdeqaaaasngveskaihimqslkeYEGKWLLFDDSEVKVTEEKDFLNLLSpissstSTPYLLFYKK 774
           *****99999999999999999999988888888877766999*******************888**************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPGLLPSDSN GLPRGSPTKK GRLSLKFFQK RETKRALDFA EPPENEQKTS EYECSEIEQI 60
VPAAQPLSPV CCEKKDIMLP FVGLNNLGNT CYLNSILQVL YFCPGFKTGV KQLFNIISKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGAAAGCA GCGATTGGTC AAAACCTTCA AAAGGAGGCG TGGCCAAAGC AGCATCATTT 60
CTATTTTCTC CACGCCGCCC CCTCCCAACC TCGCCGGCTT TGAGTTTTCC AGCCAGGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

acs:100560711

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	66.04	0.00e+00	961.00
IUUC-Apl-004204	Anas platyrhynchos	70.45	0.00e+00	918.00
IUUC-Ame-011718	Astyanax mexicanus	48.43	8.00e-170	590.00
IUUC-Bta-012552	Bos taurus	64.56	0.00e+00	944.00
IUUC-Cja-019588	Callithrix jacchus	67.00	0.00e+00	967.00
IUUC-Cfa-020211	Canis familiaris	66.96	0.00e+00	962.00
IUUC-Cpo-021551	Cavia porcellus	64.84	0.00e+00	919.00
IUUC-Csa-024186	Chlorocebus sabaeus	66.33	0.00e+00	963.00
IUUC-Cho-024739	Choloepus hoffmanni	56.51	9.00e-129	453.00
IUUC-Dre-028184	Danio rerio	47.71	1.00e-172	599.00
IUUC-Dno-029669	Dasypus novemcinctus	64.99	0.00e+00	937.00
IUUC-Dor-030168	Dipodomys ordii	62.58	0.00e+00	830.00
IUUC-Dme-031732	Drosophila melanogaster	31.11	5.00e-19	90.10
IUUC-Ete-032825	Echinops telfairi	60.24	6.00e-170	591.00
IUUC-Eca-033595	Equus caballus	64.71	0.00e+00	864.00
IUUC-Eeu-034877	Erinaceus europaeus	64.04	8.00e-103	367.00
IUUC-Fca-035381	Felis catus	66.36	0.00e+00	679.00
IUUC-Fal-037592	Ficedula albicollis	69.57	0.00e+00	958.00
IUUC-Gmo-039680	Gadus morhua	45.45	4.00e-158	551.00
IUUC-Gga-041196	Gallus gallus	70.64	0.00e+00	1014.00
IUUC-Gac-042292	Gasterosteus aculeatus	48.13	4.00e-142	498.00
IUUC-Ggo-044671	Gorilla gorilla	66.37	0.00e+00	967.00
IUUC-Hsa-047020	Homo sapiens	66.83	0.00e+00	967.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	58.93	0.00e+00	814.00
IUUC-Lch-050543	Latimeria chalumnae	56.23	0.00e+00	692.00
IUUC-Loc-052338	Lepisosteus oculatus	51.96	0.00e+00	691.00
IUUC-Laf-053707	Loxodonta africana	65.42	0.00e+00	953.00
IUUC-Mcc-055885	Macaca mulatta	66.17	0.00e+00	964.00
IUUC-Meu-056573	Macropus eugenii	59.12	0.00e+00	800.00
IUUC-Mga-059346	Meleagris gallopavo	71.56	0.00e+00	994.00
IUUC-Mmr-061612	Microcebus murinus	64.99	0.00e+00	936.00
IUUC-Mdo-062887	Monodelphis domestica	62.94	0.00e+00	869.00
IUUC-Mmu-064044	Mus musculus	65.35	0.00e+00	944.00
IUUC-Mpu-066847	Mustela putorius furo	66.29	0.00e+00	967.00
IUUC-Mlu-067684	Myotis lucifugus	65.62	0.00e+00	933.00
IUUC-Nle-070057	Nomascus leucogenys	66.25	0.00e+00	965.00
IUUC-Opr-070463	Ochotona princeps	60.03	0.00e+00	806.00
IUUC-Ont-071975	Oreochromis niloticus	46.97	2.00e-150	526.00
IUUC-Oan-073062	Ornithorhynchus anatinus	73.74	3.00e-39	153.00
IUUC-Ocu-074840	Oryctolagus cuniculus	65.62	0.00e+00	951.00
IUUC-Ola-087088	Oryzias latipes	46.32	2.00e-166	579.00
IUUC-Oga-088472	Otolemur garnettii	66.04	0.00e+00	939.00
IUUC-Oar-089498	Ovis aries	65.74	0.00e+00	949.00
IUUC-Ptr-091395	Pan troglodytes	66.83	0.00e+00	967.00
IUUC-Pan-092462	Papio anubis	66.29	0.00e+00	965.00
IUUC-Psi-093583	Pelodiscus sinensis	71.12	0.00e+00	892.00
IUUC-Pma-094644	Petromyzon marinus	37.34	5.00e-28	117.00
IUUC-Pfo-096314	Poecilia formosa	46.03	6.00e-169	587.00
IUUC-Pab-098568	Pongo abelii	66.12	0.00e+00	964.00
IUUC-Pca-100948	Procavia capensis	62.22	1.00e-130	460.00
IUUC-Pva-102853	Pteropus vampyrus	64.99	0.00e+00	940.00
IUUC-Rno-105573	Rattus norvegicus	65.87	0.00e+00	947.00
IUUC-Sha-107495	Sarcophilus harrisii	63.18	0.00e+00	740.00
IUUC-Sar-113545	Sorex araneus	57.27	0.00e+00	747.00
IUUC-Ssc-115962	Sus scrofa	65.54	0.00e+00	945.00
IUUC-Tgu-116731	Taeniopygia guttata	69.54	0.00e+00	962.00
IUUC-Tru-117893	Takifugu rubripes	46.59	8.00e-151	527.00
IUUC-Tsy-119644	Tarsius syrichta	63.13	8.00e-123	434.00
IUUC-Tni-119819	Tetraodon nigroviridis	45.06	5.00e-166	577.00
IUUC-Tbe-127272	Tupaia belangeri	61.64	0.00e+00	792.00
IUUC-Ttr-128404	Tursiops truncatus	66.25	0.00e+00	954.00
IUUC-Vpa-130205	Vicugna pacos	65.58	0.00e+00	944.00
IUUC-Xtr-132613	Xenopus tropicalis	53.85	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence