iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013218

Ensembl Protein ID

ENSBTAP00000017298.5

UniProt Accession

A7Z055; F1MF89; A7Z055_BOVIN

Genbank Protein ID

AAI53254.1

Protein Name

PLAA protein

Genbank Nucleotide ID

DAAA02022139

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000013011.5	ENSBTAT00000017298.5	ENSBTAP00000017298.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.80e-27	92.0	149	179
UBD/Beta-Prp	2.20e-66	224.2	12	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 149  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 179
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdl 81
           ++l+gh+ +v   v++  p +  +++ srd+t+++w   +++     ++++sgh+++v++v+++p+++     +++tg++D++i+v++l
   Q: 12   CSLSGHELDVRGLVCClYPPGA-FVSVSRDRTTRLWVPNSPNRgfteMHCMSGHSNFVSCVCIIPSSDvyphgLIATGGNDHNICVFSL 99
           89999*********99777776.888889********999999999******************************************* PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           +++ ++++lkgh+++v+sls+ +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g+
   Q: 100  ESPAPLYVLKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGR 182
           **********************9.9***************..9******.*********************************..88** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
           + rt++g h+d v+ l++ s+ +e++s+++d +++ w++ tgec++ + ght+ ++s+ ++pn + +v++++D+s+riW  ++g++ +t
   Q: 183  CERTFSG-HEDCVRGLAILSE-TEFLSCANDASIRRWQI-TGECLEVFYGHTNYIYSISVFPNCKDFVTTAEDRSLRIW--KHGECAQT 266
           ******9.*********9996.8****************.***************************************..9******* PP
   S: 260  lqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           + l+++s+++++v  +++  +v g++d++++++  +++
   Q: 267  IRLPAQSIWCCCV--LDNGDIVVGASDGIIRVFTESED 302
           *************..9999*************997766 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MASGSCRYRL SCSLSGHELD VRGLVCCLYP PGAFVSVSRD RTTRLWVPNS PNRGFTEMHC 60
MSGHSNFVSC VCIIPSSDVY PHGLIATGGN DHNICVFSLE SPAPLYVLKG HKNTVCSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCACTTGCA GGCGCTCTCC AGCCGCCCGC CGGGCCTCGC CGACTGACCG AGCTCGCGCG 60
GTGCCCCGGC CCCGGGCGCC GGACCCACCA GGGCTATGGC GAGCGGCTCC TGCAGATACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

KEGG

bta:506073

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	30.87	6.00e-93	335.00
IUUC-Aml-002125	Ailuropoda melanoleuca	95.87	0.00e+00	1599.00
IUUC-Atr-002554	Amborella trichopoda	31.07	1.00e-96	347.00
IUUC-Apl-004094	Anas platyrhynchos	81.44	0.00e+00	1267.00
IUUC-Aca-004726	Anolis carolinensis	80.03	0.00e+00	1318.00
IUUC-Aly-005961	Arabidopsis lyrata	33.17	2.00e-110	393.00
IUUC-Ath-006639	Arabidopsis thaliana	33.11	7.00e-106	378.00
IUUC-Ago-007772	Ashbya gossypii	29.47	1.00e-79	291.00
IUUC-Acl-008316	Aspergillus clavatus	31.89	2.00e-88	320.00
IUUC-Afl-008532	Aspergillus flavus	32.67	1.00e-91	330.00
IUUC-Afu-008950	Aspergillus fumigatus	32.03	1.00e-91	330.00
IUUC-Ani-009186	Aspergillus nidulans	33.04	3.00e-94	339.00
IUUC-Ang-009575	Aspergillus niger	31.12	5.00e-88	318.00
IUUC-Aor-010086	Aspergillus oryzae	32.67	1.00e-91	330.00
IUUC-Ate-010541	Aspergillus terreus	30.23	9.00e-88	318.00
IUUC-Ame-011633	Astyanax mexicanus	67.71	0.00e+00	1121.00
IUUC-Bgr-012292	Blumeria graminis	30.58	2.00e-92	333.00
IUUC-Bci-013876	Botrytis cinerea	32.56	2.00e-94	340.00
IUUC-Bdi-014810	Brachypodium distachyon	33.25	1.00e-107	384.00
IUUC-Bol-016006	Brassica oleracea	32.90	2.00e-109	390.00
IUUC-Bra-017593	Brassica rapa	33.16	9.00e-110	391.00
IUUC-Cel-018703	Caenorhabditis elegans	27.99	1.00e-73	271.00
IUUC-Cja-019270	Callithrix jacchus	92.96	0.00e+00	1565.00
IUUC-Cfa-021262	Canis familiaris	95.25	0.00e+00	1585.00
IUUC-Cpo-021449	Cavia porcellus	88.36	0.00e+00	1438.00
IUUC-Csa-024140	Chlorocebus sabaeus	93.84	0.00e+00	1576.00
IUUC-Cho-024923	Choloepus hoffmanni	93.22	0.00e+00	762.00
IUUC-Cin-025373	Ciona intestinalis	40.74	6.00e-176	610.00
IUUC-Csv-026324	Ciona savignyi	42.01	0.00e+00	653.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	31.61	1.00e-89	324.00
IUUC-Cne-026998	Cryptococcus neoformans	31.55	8.00e-89	321.00
IUUC-Cme-027154	Cyanidioschyzon merolae	30.14	3.00e-57	216.00
IUUC-Dre-028674	Danio rerio	66.00	0.00e+00	1101.00
IUUC-Dno-028966	Dasypus novemcinctus	92.96	0.00e+00	1561.00
IUUC-Dor-030343	Dipodomys ordii	87.15	0.00e+00	905.00
IUUC-Dse-031385	Dothistroma septosporum	31.15	3.00e-86	313.00
IUUC-Dme-032044	Drosophila melanogaster	36.36	1.00e-127	450.00
IUUC-Ete-032506	Echinops telfairi	83.79	0.00e+00	828.00
IUUC-Eca-033547	Equus caballus	96.23	0.00e+00	1607.00
IUUC-Eeu-034462	Erinaceus europaeus	79.65	0.00e+00	676.00
IUUC-Fca-035893	Felis catus	95.35	0.00e+00	1595.00
IUUC-Fal-037235	Ficedula albicollis	81.56	0.00e+00	1372.00
IUUC-Fox-037836	Fusarium oxysporum	31.61	5.00e-96	345.00
IUUC-Fso-038251	Fusarium solani	30.89	1.00e-94	340.00
IUUC-Gmo-038648	Gadus morhua	66.27	0.00e+00	966.00
IUUC-Ggr-039867	Gaeumannomyces graminis	31.47	4.00e-86	312.00
IUUC-Gga-040989	Gallus gallus	79.80	0.00e+00	1323.00
IUUC-Gac-041344	Gasterosteus aculeatus	66.96	0.00e+00	1069.00
IUUC-Gma-043067	Glycine max	31.96	4.00e-106	379.00
IUUC-Ggo-045009	Gorilla gorilla	93.28	0.00e+00	1201.00
IUUC-Hsa-046807	Homo sapiens	93.84	0.00e+00	1572.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	94.35	0.00e+00	1579.00
IUUC-Kpa-049134	Komagataella pastoris	43.63	3.00e-88	319.00
IUUC-Lch-049597	Latimeria chalumnae	72.78	0.00e+00	738.00
IUUC-Lpe-050821	Leersia perrieri	31.19	2.00e-99	356.00
IUUC-Loc-051849	Lepisosteus oculatus	72.48	0.00e+00	1206.00
IUUC-Lma-053297	Leptosphaeria maculans	34.20	3.00e-104	372.00
IUUC-Laf-053495	Loxodonta africana	93.24	0.00e+00	1557.00
IUUC-Meu-055983	Macropus eugenii	80.86	0.00e+00	649.00
IUUC-Mor-057006	Magnaporthe oryzae	36.80	1.00e-73	271.00
IUUC-Mpo-057465	Magnaporthe poae	35.57	2.00e-74	273.00
IUUC-Mtr-058374	Medicago truncatula	33.42	7.00e-117	414.00
IUUC-Mla-058895	Melampsora laricipopulina	36.11	5.00e-78	285.00
IUUC-Mvi-060297	Microbotryum violaceum	37.20	3.00e-112	399.00
IUUC-Mmr-060810	Microcebus murinus	88.88	0.00e+00	1458.00
IUUC-Mdo-062671	Monodelphis domestica	87.45	0.00e+00	1437.00
IUUC-Mmu-063536	Mus musculus	92.71	0.00e+00	1526.00
IUUC-Mac-064902	Musa acuminata	31.80	3.00e-100	359.00
IUUC-Mpu-066085	Mustela putorius furo	95.85	0.00e+00	1605.00
IUUC-Mlu-067907	Myotis lucifugus	92.53	0.00e+00	996.00
IUUC-Nfi-068457	Neosartorya fischeri	31.86	4.00e-74	272.00
IUUC-Ncr-068622	Neurospora crassa	30.90	3.00e-97	349.00
IUUC-Nle-069049	Nomascus leucogenys	92.84	0.00e+00	1543.00
IUUC-Opr-071013	Ochotona princeps	73.05	0.00e+00	647.00
IUUC-Ont-071339	Oreochromis niloticus	69.41	0.00e+00	1150.00
IUUC-Oan-073353	Ornithorhynchus anatinus	82.98	9.00e-112	395.00
IUUC-Ocu-074625	Oryctolagus cuniculus	93.59	0.00e+00	1571.00
IUUC-Oba-075226	Oryza barthii	28.91	2.00e-86	313.00
IUUC-Obr-076875	Oryza brachyantha	32.54	4.00e-111	395.00
IUUC-Ogl-077057	Oryza glaberrima	32.17	6.00e-111	394.00
IUUC-Ogu-078156	Oryza glumaepatula	32.00	9.00e-111	394.00
IUUC-Oin-079373	Oryza indica	31.80	2.00e-109	390.00
IUUC-Olo-080849	Oryza longistaminata	29.32	2.00e-74	273.00
IUUC-Ome-081654	Oryza meridionalis	28.39	4.00e-86	312.00
IUUC-Oni-082221	Oryza nivara	28.77	6.00e-89	322.00
IUUC-Opu-084103	Oryza punctata	29.04	1.00e-86	314.00
IUUC-Oru-084751	Oryza rufipogon	28.16	5.00e-85	308.00
IUUC-Osa-085584	Oryza sativa	31.76	9.00e-110	391.00
IUUC-Ola-086974	Oryzias latipes	68.22	0.00e+00	1146.00
IUUC-Oga-088052	Otolemur garnettii	89.08	0.00e+00	1476.00
IUUC-Oar-089509	Ovis aries	98.38	0.00e+00	1631.00
IUUC-Ptr-090911	Pan troglodytes	93.97	0.00e+00	1575.00
IUUC-Pan-092141	Papio anubis	93.37	0.00e+00	1566.00
IUUC-Psi-093543	Pelodiscus sinensis	82.43	0.00e+00	1286.00
IUUC-Pno-094952	Phaeosphaeria nodorum	33.16	2.00e-98	353.00
IUUC-Ppa-095881	Physcomitrella patens	32.96	6.00e-113	401.00
IUUC-Pfo-096739	Poecilia formosa	67.91	0.00e+00	1136.00
IUUC-Pab-098641	Pongo abelii	93.84	0.00e+00	1571.00
IUUC-Pop-099621	Populus trichocarpa	32.00	2.00e-105	376.00
IUUC-Pca-100599	Procavia capensis	85.25	0.00e+00	1315.00
IUUC-Ppe-101874	Prunus persica	32.13	4.00e-111	395.00
IUUC-Pva-103009	Pteropus vampyrus	91.48	0.00e+00	1290.00
IUUC-Pgr-103260	Puccinia graminis	32.48	1.00e-94	340.00
IUUC-Ptt-103711	Puccinia triticina	31.98	3.00e-92	333.00
IUUC-Pte-104337	Pyrenophora teres	32.60	4.00e-94	339.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	32.73	3.00e-95	343.00
IUUC-Rno-105273	Rattus norvegicus	93.09	0.00e+00	1565.00
IUUC-Sce-106351	Saccharomyces cerevisiae	39.29	2.00e-80	293.00
IUUC-Sha-106758	Sarcophilus harrisii	87.12	0.00e+00	1440.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	39.78	1.00e-95	343.00
IUUC-Spo-108093	Schizosaccharomyces pombe	34.83	7.00e-102	364.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	39.32	3.00e-91	329.00
IUUC-Smo-109368	Selaginella moellendorffii	31.44	2.00e-99	356.00
IUUC-Sit-109699	Setaria italica	33.80	1.00e-112	400.00
IUUC-Sly-111063	Solanum lycopersicum	32.51	1.00e-104	374.00
IUUC-Sar-113199	Sorex araneus	94.99	0.00e+00	817.00
IUUC-Sbi-114745	Sorghum bicolor	32.67	8.00e-104	371.00
IUUC-Sre-115080	Sporisorium reilianum	33.37	4.00e-108	385.00
IUUC-Ssc-115666	Sus scrofa	95.50	0.00e+00	1595.00
IUUC-Tgu-116877	Taeniopygia guttata	80.80	0.00e+00	1364.00
IUUC-Tru-117580	Takifugu rubripes	67.12	0.00e+00	1131.00
IUUC-Tsy-118946	Tarsius syrichta	94.64	0.00e+00	1457.00
IUUC-Tni-119755	Tetraodon nigroviridis	64.74	0.00e+00	1057.00
IUUC-Tca-120977	Theobroma cacao	31.29	3.00e-101	362.00
IUUC-Tre-122217	Trichoderma reesei	32.42	2.00e-97	350.00
IUUC-Tvi-122671	Trichoderma virens	30.93	1.00e-94	340.00
IUUC-Tae-125581	Triticum aestivum	33.12	8.00e-109	387.00
IUUC-Tur-126404	Triticum urartu	23.89	3.00e-22	100.00
IUUC-Tme-126971	Tuber melanosporum	34.76	1.00e-114	407.00
IUUC-Tbe-127858	Tupaia belangeri	75.11	0.00e+00	644.00
IUUC-Ttr-128173	Tursiops truncatus	94.60	0.00e+00	1552.00
IUUC-Uma-129322	Ustilago maydis	33.58	2.00e-108	387.00
IUUC-Vda-129682	Verticillium dahliae	32.25	5.00e-93	335.00
IUUC-Vpa-130607	Vicugna pacos	94.10	0.00e+00	1441.00
IUUC-Vvi-131153	Vitis vinifera	33.72	7.00e-113	401.00
IUUC-Xtr-132208	Xenopus tropicalis	75.22	0.00e+00	1243.00
IUUC-Xma-133098	Xiphophorus maculatus	68.62	0.00e+00	1133.00
IUUC-Yli-134646	Yarrowia lipolytica	39.21	1.00e-94	341.00
IUUC-Zma-135920	Zea mays	30.96	3.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence