iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089509

Ensembl Protein ID

ENSOARP00000015586.1

UniProt Accession

W5PYQ1; W5PYQ1_SHEEP

Genbank Protein ID

ENSOARP00000015586

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01050795

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000014522.1	ENSOART00000015817.1	ENSOARP00000015586.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-26	91.8	184	214
UBD/Beta-Prp	3.20e-65	220.4	47	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 184  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 214
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdl 81
           ++l+gh+ +v   v++  p +  +++ srd+t+++w  ++++     ++++sgh+++v++v+++p+++     +++tg++D++i++++l
   Q: 47   CSLSGHELDVRGLVCClYPPGA-FVSVSRDRTTRLWVPDSPNRgfteMHCMSGHSNFVSCVCIIPSSDvyphgLIATGGNDHNICIFSL 134
           89999*********99777776.888889***********99999******************************************** PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           +++ ++++lkgh+++v+sls+ +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g+
   Q: 135  ESPAPLYVLKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGR 217
           **********************9.9***************..9******.*********************************..88** PP
   S: 171  llrtl....tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgd 255
           + rt+    tg h+d v+ l++ s+ +e++s+++d +++ w++ tgec++ + ght+ ++s+ ++pn + +v++++D+s+riW  ++g+
   Q: 218  CERTFsdfnTG-HEDCVRGLAILSE-TEFLSCANDASIRRWQI-TGECLEVFYGHTNYIYSISVFPNCKDFVTTAEDRSLRIW--KHGE 301
           *****999666.*********9996.8****************.***************************************..9*** PP
   S: 256  llktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           + +t+ l+++s+++++v  +++  +v g++d++++++  +++
   Q: 302  CAQTIRLPAQSIWCCCV--LDNGDIVVGASDGIIRVFTESED 341
           *****************..9999*************997766 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MNSGVLVRVA VSLGPLGAPL PCRPSAPAVS GPTGAMASGS CRYRLSCSLS GHELDVRGLV 60
CCLYPPGAFV SVSRDRTTRL WVPDSPNRGF TEMHCMSGHS NFVSCVCIIP SSDVYPHGLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGAATT CCGGTGTGCT TGTCAGGGTT GCTGTGTCAC TCGGCCCTCT CGGCGCGCCC 60
CTTCCCTGCC GCCCTTCCGC GCCGGCCGTC TCGGGACCCA CCGGGGCGAT GGCGAGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016005--F:phospholipase A2 activator activity
GO:0006954--P:inflammatory response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	30.74	1.00e-90	327.00
IUUC-Aml-002125	Ailuropoda melanoleuca	95.79	0.00e+00	1603.00
IUUC-Atr-002554	Amborella trichopoda	30.83	9.00e-95	341.00
IUUC-Apl-004094	Anas platyrhynchos	81.08	0.00e+00	1252.00
IUUC-Aca-004726	Anolis carolinensis	79.95	0.00e+00	1306.00
IUUC-Aly-005961	Arabidopsis lyrata	32.88	4.00e-107	382.00
IUUC-Ath-006639	Arabidopsis thaliana	32.77	1.00e-102	367.00
IUUC-Ago-007772	Ashbya gossypii	36.38	2.00e-73	270.00
IUUC-Acl-008316	Aspergillus clavatus	31.99	1.00e-86	314.00
IUUC-Afl-008532	Aspergillus flavus	32.63	6.00e-90	325.00
IUUC-Afu-008950	Aspergillus fumigatus	32.25	2.00e-90	327.00
IUUC-Ani-009186	Aspergillus nidulans	33.62	9.00e-94	338.00
IUUC-Ang-009575	Aspergillus niger	31.10	2.00e-86	313.00
IUUC-Aor-010086	Aspergillus oryzae	32.63	6.00e-90	325.00
IUUC-Ate-010541	Aspergillus terreus	30.42	5.00e-86	312.00
IUUC-Ame-011633	Astyanax mexicanus	66.87	0.00e+00	1104.00
IUUC-Bgr-012292	Blumeria graminis	30.06	7.00e-90	325.00
IUUC-Bta-013218	Bos taurus	98.38	0.00e+00	1631.00
IUUC-Bci-013876	Botrytis cinerea	31.75	1.00e-91	330.00
IUUC-Bdi-014810	Brachypodium distachyon	32.95	2.00e-104	373.00
IUUC-Bol-016006	Brassica oleracea	32.60	4.00e-106	379.00
IUUC-Bra-017593	Brassica rapa	32.86	3.00e-106	379.00
IUUC-Cel-018703	Caenorhabditis elegans	27.82	3.00e-69	256.00
IUUC-Cja-019270	Callithrix jacchus	92.65	0.00e+00	1551.00
IUUC-Cfa-021262	Canis familiaris	95.28	0.00e+00	1584.00
IUUC-Cpo-021449	Cavia porcellus	87.56	0.00e+00	1436.00
IUUC-Csa-024140	Chlorocebus sabaeus	93.28	0.00e+00	1561.00
IUUC-Cho-024923	Choloepus hoffmanni	92.52	0.00e+00	751.00
IUUC-Cin-025373	Ciona intestinalis	40.02	6.00e-171	594.00
IUUC-Csv-026324	Ciona savignyi	41.71	0.00e+00	640.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	32.00	1.00e-88	321.00
IUUC-Cne-026998	Cryptococcus neoformans	31.44	1.00e-86	314.00
IUUC-Cme-027154	Cyanidioschyzon merolae	29.58	2.00e-53	203.00
IUUC-Dre-028674	Danio rerio	65.30	0.00e+00	1085.00
IUUC-Dno-028966	Dasypus novemcinctus	88.55	0.00e+00	1566.00
IUUC-Dor-030343	Dipodomys ordii	86.64	0.00e+00	895.00
IUUC-Dse-031385	Dothistroma septosporum	31.19	7.00e-84	305.00
IUUC-Dme-032044	Drosophila melanogaster	36.17	1.00e-123	437.00
IUUC-Ete-032506	Echinops telfairi	82.51	0.00e+00	819.00
IUUC-Eca-033547	Equus caballus	95.64	0.00e+00	1592.00
IUUC-Eeu-034462	Erinaceus europaeus	79.03	0.00e+00	677.00
IUUC-Fca-035893	Felis catus	95.02	0.00e+00	1583.00
IUUC-Fal-037235	Ficedula albicollis	79.98	0.00e+00	1361.00
IUUC-Fox-037836	Fusarium oxysporum	31.07	2.00e-95	343.00
IUUC-Fso-038251	Fusarium solani	30.90	2.00e-93	337.00
IUUC-Gmo-038648	Gadus morhua	65.20	0.00e+00	953.00
IUUC-Ggr-039867	Gaeumannomyces graminis	31.01	3.00e-85	310.00
IUUC-Gga-040989	Gallus gallus	79.23	0.00e+00	1308.00
IUUC-Gac-041344	Gasterosteus aculeatus	65.60	0.00e+00	1052.00
IUUC-Gma-043067	Glycine max	31.56	8.00e-104	371.00
IUUC-Ggo-045009	Gorilla gorilla	93.20	0.00e+00	1202.00
IUUC-Hsa-046807	Homo sapiens	93.52	0.00e+00	1560.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	94.03	0.00e+00	1568.00
IUUC-Kpa-049134	Komagataella pastoris	43.25	4.00e-86	312.00
IUUC-Lch-049597	Latimeria chalumnae	72.18	0.00e+00	732.00
IUUC-Lpe-050821	Leersia perrieri	30.47	1.00e-95	344.00
IUUC-Loc-051849	Lepisosteus oculatus	71.73	0.00e+00	1190.00
IUUC-Lma-053297	Leptosphaeria maculans	33.46	2.00e-103	369.00
IUUC-Laf-053495	Loxodonta africana	93.03	0.00e+00	1556.00
IUUC-Meu-055983	Macropus eugenii	80.50	0.00e+00	640.00
IUUC-Mor-057006	Magnaporthe oryzae	36.17	2.00e-73	270.00
IUUC-Mpo-057465	Magnaporthe poae	36.05	2.00e-74	273.00
IUUC-Mtr-058374	Medicago truncatula	33.13	7.00e-114	404.00
IUUC-Mla-058895	Melampsora laricipopulina	35.81	3.00e-76	278.00
IUUC-Mvi-060297	Microbotryum violaceum	36.26	3.00e-108	385.00
IUUC-Mmr-060810	Microcebus murinus	88.60	0.00e+00	1452.00
IUUC-Mdo-062671	Monodelphis domestica	87.06	0.00e+00	1423.00
IUUC-Mmu-063536	Mus musculus	92.28	0.00e+00	1514.00
IUUC-Mac-064902	Musa acuminata	31.52	9.00e-99	354.00
IUUC-Mpu-066085	Mustela putorius furo	95.52	0.00e+00	1592.00
IUUC-Mlu-067907	Myotis lucifugus	92.59	0.00e+00	996.00
IUUC-Nfi-068457	Neosartorya fischeri	31.69	2.00e-72	266.00
IUUC-Ncr-068622	Neurospora crassa	30.72	2.00e-96	347.00
IUUC-Nle-069049	Nomascus leucogenys	92.53	0.00e+00	1530.00
IUUC-Opr-071013	Ochotona princeps	72.79	0.00e+00	638.00
IUUC-Ont-071339	Oreochromis niloticus	68.28	0.00e+00	1134.00
IUUC-Oan-073353	Ornithorhynchus anatinus	83.40	6.00e-112	396.00
IUUC-Ocu-074625	Oryctolagus cuniculus	93.28	0.00e+00	1558.00
IUUC-Oba-075226	Oryza barthii	28.54	4.00e-84	305.00
IUUC-Obr-076875	Oryza brachyantha	32.51	1.00e-108	387.00
IUUC-Ogl-077057	Oryza glaberrima	31.89	8.00e-108	384.00
IUUC-Ogu-078156	Oryza glumaepatula	31.66	3.00e-108	386.00
IUUC-Oin-079373	Oryza indica	31.52	1.00e-106	380.00
IUUC-Olo-080849	Oryza longistaminata	28.44	3.00e-71	263.00
IUUC-Ome-081654	Oryza meridionalis	28.10	1.00e-84	307.00
IUUC-Oni-082221	Oryza nivara	28.80	2.00e-87	317.00
IUUC-Opu-084103	Oryza punctata	29.42	2.00e-85	310.00
IUUC-Oru-084751	Oryza rufipogon	27.87	2.00e-83	303.00
IUUC-Osa-085584	Oryza sativa	31.54	2.00e-107	383.00
IUUC-Ola-086974	Oryzias latipes	67.79	0.00e+00	1138.00
IUUC-Oga-088052	Otolemur garnettii	88.68	0.00e+00	1462.00
IUUC-Ptr-090911	Pan troglodytes	93.65	0.00e+00	1563.00
IUUC-Pan-092141	Papio anubis	93.28	0.00e+00	1564.00
IUUC-Psi-093543	Pelodiscus sinensis	82.06	0.00e+00	1273.00
IUUC-Pno-094952	Phaeosphaeria nodorum	32.60	1.00e-96	347.00
IUUC-Ppa-095881	Physcomitrella patens	32.93	7.00e-111	394.00
IUUC-Pfo-096739	Poecilia formosa	67.20	0.00e+00	1119.00
IUUC-Pab-098641	Pongo abelii	88.81	0.00e+00	1590.00
IUUC-Pop-099621	Populus trichocarpa	31.72	2.00e-102	366.00
IUUC-Pca-100599	Procavia capensis	84.73	0.00e+00	1301.00
IUUC-Ppe-101874	Prunus persica	31.73	3.00e-108	385.00
IUUC-Pva-103009	Pteropus vampyrus	90.55	0.00e+00	1272.00
IUUC-Pgr-103260	Puccinia graminis	32.66	6.00e-93	335.00
IUUC-Ptt-103711	Puccinia triticina	31.57	5.00e-88	318.00
IUUC-Pte-104337	Pyrenophora teres	32.05	2.00e-93	337.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	32.18	4.00e-94	339.00
IUUC-Rno-105273	Rattus norvegicus	92.65	0.00e+00	1551.00
IUUC-Sce-106351	Saccharomyces cerevisiae	39.02	8.00e-80	291.00
IUUC-Sha-106758	Sarcophilus harrisii	86.58	0.00e+00	1432.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	39.43	4.00e-94	339.00
IUUC-Spo-108093	Schizosaccharomyces pombe	34.51	2.00e-100	359.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	31.23	2.00e-90	327.00
IUUC-Smo-109368	Selaginella moellendorffii	31.00	6.00e-96	345.00
IUUC-Sit-109699	Setaria italica	33.38	7.00e-109	388.00
IUUC-Sly-111063	Solanum lycopersicum	32.22	2.00e-101	363.00
IUUC-Sar-113199	Sorex araneus	94.79	0.00e+00	814.00
IUUC-Sbi-114745	Sorghum bicolor	32.24	6.00e-100	358.00
IUUC-Sre-115080	Sporisorium reilianum	33.74	1.00e-106	380.00
IUUC-Ssc-115666	Sus scrofa	95.54	0.00e+00	1605.00
IUUC-Tgu-116877	Taeniopygia guttata	80.62	0.00e+00	1353.00
IUUC-Tru-117580	Takifugu rubripes	66.25	0.00e+00	1114.00
IUUC-Tsy-118946	Tarsius syrichta	93.89	0.00e+00	1442.00
IUUC-Tni-119755	Tetraodon nigroviridis	63.93	0.00e+00	1043.00
IUUC-Tca-120977	Theobroma cacao	30.54	2.00e-98	353.00
IUUC-Tre-122217	Trichoderma reesei	32.15	4.00e-97	348.00
IUUC-Tvi-122671	Trichoderma virens	30.82	7.00e-95	341.00
IUUC-Tae-125234	Triticum aestivum	32.84	3.00e-105	376.00
IUUC-Tur-126404	Triticum urartu	24.03	2.00e-22	101.00
IUUC-Tme-126971	Tuber melanosporum	34.27	1.00e-112	400.00
IUUC-Tbe-127858	Tupaia belangeri	75.06	0.00e+00	637.00
IUUC-Ttr-128173	Tursiops truncatus	94.27	0.00e+00	1540.00
IUUC-Uma-129322	Ustilago maydis	33.58	4.00e-107	382.00
IUUC-Vda-129682	Verticillium dahliae	32.87	2.00e-92	333.00
IUUC-Vpa-130607	Vicugna pacos	93.49	0.00e+00	1425.00
IUUC-Vvi-131153	Vitis vinifera	32.73	2.00e-110	393.00
IUUC-Xtr-132208	Xenopus tropicalis	74.56	0.00e+00	1229.00
IUUC-Xma-133098	Xiphophorus maculatus	68.14	0.00e+00	1117.00
IUUC-Yli-134646	Yarrowia lipolytica	38.93	3.00e-93	335.00
IUUC-Zma-135920	Zea mays	30.90	3.00e-91	329.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence