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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046511
Ensembl Protein ID ENSP00000450661.1
UniProt Accession Q64LD2; A8K7E5; Q6NVV6; Q86TQ4; Q9BTK5; WDR25_HUMAN
Genbank Protein ID AAQ63174.1; BAF84649.1; AAH03641.1; CAD66574.1
Protein Name WD repeat-containing protein 25
Genbank Nucleotide ID AY295082; AK291960; AL135838; BX248767
Gene Name WDR25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000176473.13 ENST00000554998.5 ENSP00000450661.1
ENSG00000176473.13 ENST00000557710.5 ENSP00000451070.1
ENSG00000176473.13 ENST00000542471.2 ENSP00000441903.2
ENSG00000176473.13 ENST00000555201.1 ENSP00000452235.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBasecircRNADbCircNet
miRTarBasemicroRNATRANSFACRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Disease-associated Variation
ClinVarGWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.90e-18 65.9 244 286
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf....sd.tllvsGsdDgtikvW.Dlrtgvllk 37
           gH ++v+ +++    s  ++l+s s D+t kvW  +++g++l+
   Q: 244  GHRGPVNTIQWcpvlSKsHMLLSTSMDKTFKVWnAVDSGHCLQ 286
           8*************95569**************8888888877 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MTARTLSLMA SLVAYDDSDS EAETEHAGSF NATGQQKDTS GVARPPGQDF ASGTLDVPKA 60
GAQPTKHGSC EDPGGYRLPL AQLGRSDWGS CPSQRLQWPG KEPQVTFPIK EPSCSSLWTS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046511|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCGCGGCG TCGCGTCGGA ACGTGACTGG ATGGTAGTGT GCTGGCCGGT CTGCCTCCGG 60
GAGAACCGAG CGCTTCCGGT GCGTGTGGTG AGCGGCGGGC CCCGGGCTGG AGGGGCCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046511|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR023302--Pept_S9A_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
KEGG hsa:79446
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001588 Ailuropoda melanoleuca 81.40 0.00e+00 887.00
IUUC-Atr-003155 Amborella trichopoda 35.87 3.00e-63 236.00
IUUC-Apl-003544 Anas platyrhynchos 69.19 9.00e-89 319.00
IUUC-Aly-006510 Arabidopsis lyrata 35.78 8.00e-67 247.00
IUUC-Ath-007329 Arabidopsis thaliana 36.31 4.00e-68 252.00
IUUC-Ame-010607 Astyanax mexicanus 58.41 7.00e-73 266.00
IUUC-Bta-013542 Bos taurus 76.06 0.00e+00 816.00
IUUC-Bdi-014736 Brachypodium distachyon 36.91 2.00e-68 253.00
IUUC-Bol-016112 Brassica oleracea 36.42 4.00e-68 251.00
IUUC-Bra-016685 Brassica rapa 36.10 5.00e-67 248.00
IUUC-Cja-018883 Callithrix jacchus 90.61 0.00e+00 975.00
IUUC-Cfa-021278 Canis familiaris 79.93 0.00e+00 870.00
IUUC-Cpo-022449 Cavia porcellus 80.53 6.00e-169 586.00
IUUC-Csa-023916 Chlorocebus sabaeus 96.08 0.00e+00 1005.00
IUUC-Cin-025210 Ciona intestinalis 35.14 1.00e-40 159.00
IUUC-Csv-026371 Ciona savignyi 32.45 4.00e-42 164.00
IUUC-Dno-029053 Dasypus novemcinctus 63.54 5.00e-109 387.00
IUUC-Dor-030299 Dipodomys ordii 69.15 1.00e-140 492.00
IUUC-Ete-032974 Echinops telfairi 48.78 4.00e-89 322.00
IUUC-Eca-033484 Equus caballus 78.08 0.00e+00 816.00
IUUC-Fca-035673 Felis catus 80.66 0.00e+00 852.00
IUUC-Fal-036795 Ficedula albicollis 66.97 2.00e-140 491.00
IUUC-Gmo-039062 Gadus morhua 54.95 2.00e-91 328.00
IUUC-Gga-040773 Gallus gallus 64.41 2.00e-116 411.00
IUUC-Gac-042364 Gasterosteus aculeatus 54.98 1.00e-92 332.00
IUUC-Gma-043100 Glycine max 36.36 8.00e-65 241.00
IUUC-Ggo-045220 Gorilla gorilla 98.16 0.00e+00 1047.00
IUUC-Hvu-047431 Hordeum vulgare 36.77 1.00e-64 240.00
IUUC-Lch-049590 Latimeria chalumnae 65.31 1.00e-110 392.00
IUUC-Lpe-050810 Leersia perrieri 37.23 2.00e-51 196.00
IUUC-Loc-052196 Lepisosteus oculatus 55.91 3.00e-123 435.00
IUUC-Laf-053481 Loxodonta africana 74.86 5.00e-151 526.00
IUUC-Mcc-055622 Macaca mulatta 95.21 0.00e+00 1012.00
IUUC-Meu-055978 Macropus eugenii 36.06 7.00e-42 164.00
IUUC-Mtr-058041 Medicago truncatula 36.36 6.00e-64 238.00
IUUC-Mga-060149 Meleagris gallopavo 68.90 1.00e-89 322.00
IUUC-Mmr-061552 Microcebus murinus 82.50 0.00e+00 909.00
IUUC-Mdo-061969 Monodelphis domestica 52.60 3.00e-159 555.00
IUUC-Mmu-063343 Mus musculus 78.92 0.00e+00 779.00
IUUC-Mac-065079 Musa acuminata 34.50 5.00e-57 215.00
IUUC-Mpu-065949 Mustela putorius furo 80.33 0.00e+00 765.00
IUUC-Mlu-067523 Myotis lucifugus 76.22 0.00e+00 699.00
IUUC-Nle-069645 Nomascus leucogenys 96.71 0.00e+00 787.00
IUUC-Ont-072361 Oreochromis niloticus 46.92 1.00e-112 400.00
IUUC-Ocu-074916 Oryctolagus cuniculus 74.16 1.00e-151 530.00
IUUC-Oba-075367 Oryza barthii 37.04 4.00e-59 222.00
IUUC-Obr-076738 Oryza brachyantha 37.50 1.00e-63 237.00
IUUC-Ogu-078590 Oryza glumaepatula 37.04 3.00e-59 222.00
IUUC-Oin-079678 Oryza indica 37.18 2.00e-64 239.00
IUUC-Olo-080453 Oryza longistaminata 37.18 3.00e-62 231.00
IUUC-Ome-081794 Oryza meridionalis 39.09 4.00e-53 201.00
IUUC-Oni-082432 Oryza nivara 37.18 1.00e-64 240.00
IUUC-Opu-083897 Oryza punctata 37.38 8.00e-65 241.00
IUUC-Oru-085068 Oryza rufipogon 35.29 1.00e-56 214.00
IUUC-Osa-085805 Oryza sativa 37.18 1.00e-64 240.00
IUUC-Ola-087567 Oryzias latipes 55.15 3.00e-93 334.00
IUUC-Oga-088168 Otolemur garnettii 83.40 0.00e+00 890.00
IUUC-Oar-090158 Ovis aries 69.43 0.00e+00 676.00
IUUC-Ptr-090913 Pan troglodytes 88.42 0.00e+00 941.00
IUUC-Pan-092157 Papio anubis 96.32 0.00e+00 1020.00
IUUC-Psi-093817 Pelodiscus sinensis 69.12 5.00e-118 416.00
IUUC-Pma-094263 Petromyzon marinus 56.98 5.00e-58 216.00
IUUC-Ppa-095302 Physcomitrella patens 37.34 7.00e-66 244.00
IUUC-Pfo-097526 Poecilia formosa 49.60 2.00e-110 392.00
IUUC-Pab-098152 Pongo abelii 93.13 0.00e+00 978.00
IUUC-Pop-099987 Populus trichocarpa 38.61 1.00e-70 260.00
IUUC-Pca-100527 Procavia capensis 66.46 3.00e-121 429.00
IUUC-Ppe-101575 Prunus persica 34.08 1.00e-66 247.00
IUUC-Pva-102942 Pteropus vampyrus 77.25 0.00e+00 840.00
IUUC-Rno-104857 Rattus norvegicus 77.61 0.00e+00 798.00
IUUC-Sha-106763 Sarcophilus harrisii 50.72 7.00e-157 547.00
IUUC-Sit-110488 Setaria italica 38.46 3.00e-65 242.00
IUUC-Sly-110893 Solanum lycopersicum 36.57 9.00e-63 234.00
IUUC-Stu-112566 Solanum tuberosum 35.92 3.00e-61 229.00
IUUC-Sar-113617 Sorex araneus 60.42 1.00e-131 462.00
IUUC-Sbi-114566 Sorghum bicolor 37.06 7.00e-67 248.00
IUUC-Tgu-117015 Taeniopygia guttata 67.28 4.00e-140 490.00
IUUC-Tsy-119467 Tarsius syrichta 70.36 4.00e-121 427.00
IUUC-Tca-121587 Theobroma cacao 35.22 2.00e-65 243.00
IUUC-Tae-123717 Triticum aestivum 37.42 3.00e-65 242.00
IUUC-Tbe-127502 Tupaia belangeri 70.17 0.00e+00 688.00
IUUC-Ttr-129033 Tursiops truncatus 82.69 0.00e+00 899.00
IUUC-Vvi-131505 Vitis vinifera 36.10 4.00e-67 248.00
IUUC-Xtr-132851 Xenopus tropicalis 61.06 6.00e-79 286.00
IUUC-Xma-133463 Xiphophorus maculatus 50.13 7.00e-111 394.00
Created Date 25-Jun-2017

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