iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118040

UUCD1 version

UUC-TaR-00664

Ensembl Protein ID

ENSTRUP00000031478.1

UniProt Accession

H2U3G7; H2U3G7_TAKRU

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000012430.1	ENSTRUT00000031601.1	ENSTRUP00000031478.1
ENSTRUG00000012430.1	ENSTRUT00000031602.1	ENSTRUP00000031479.1
ENSTRUG00000012430.1	ENSTRUT00000031603.1	ENSTRUP00000031480.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-58	191.0	1681	1713
UBD/Beta-Prp	1.20e-131	439.6	722	936

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           +++++la      + ++s+sdDgti++WDl + +
   Q: 1681 GGIWGLAThpfK-DVFISASDDGTIRIWDLADKK 1713
           358887765422.679*************98765 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlk 91
           h+++ + +++++p k+++a++  +rd+ i vwd++t k+l+ l   h+++v++++f  dgk lv+++ D  + i +wd ++g+ + + +
   Q: 722  HDDDIL-SLTVHPLKDFVASAqvGRDAAIHVWDIQTLKCLSLLkGHHSQGVSSLEFTADGKSLVSVGIDefHSIVIWDWKKGERLAKAR 809
           334434.4777788888777533688888888888888888884446778888888888888888888877788888888888888888 PP
   S: 92   ghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           gh++++  ++++p  +dklv+ +  + i+ w+++ g    +     + g+ ++ +++++  +++l++sG++++ + +W  +  +l++t 
   Q: 810  GHKEKIFVVKSNPfRTDKLVTVG-MKHIKFWQHSGGGLTFKrgifGNLGKLETMMSTCFGRSEDLVFSGATNGDIYIW--RDTTLIKTI 895
           88888888888886668888776.788888888877766666877677778888888888888888888888888888..778888888 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           +  h+++v s+   +  k +v+g++dg v+lwd    +c++t+ 
   Q: 896  KA-HDGPVFSMCSLD--KGFVTGGKDGVVELWDDMFDRCLKTYA 936
           77.888888888777..568888888888888888888888775 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSDKTAPRCQ LRLEWIHGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR DHTQKFYLGH 60
NDDIISLAIH PDKVQVATGQ VGKDPFICIW DTYGMQTVSI LRDVHTHGVA CLAFDAEGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGATA AGACGGCGCC ACGCTGCCAG CTAAGGCTGG AGTGGATCCA TGGATACAGG 60
GGCCACCAGT GTCGGAATAA CCTGTACTAC ACTGCGGGAA AAGAGGTGGT GTACTTTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	79.18	0.00e+00	3203.00
IUUC-Apl-003604	Anas platyrhynchos	78.46	0.00e+00	3168.00
IUUC-Aca-004572	Anolis carolinensis	76.25	0.00e+00	3104.00
IUUC-Ame-010713	Astyanax mexicanus	84.09	0.00e+00	3387.00
IUUC-Bta-012812	Bos taurus	78.72	0.00e+00	3190.00
IUUC-Cja-019191	Callithrix jacchus	78.28	0.00e+00	3156.00
IUUC-Cfa-020041	Canis familiaris	79.06	0.00e+00	2973.00
IUUC-Csa-023689	Chlorocebus sabaeus	77.95	0.00e+00	3075.00
IUUC-Cho-025038	Choloepus hoffmanni	77.09	0.00e+00	1190.00
IUUC-Cin-025205	Ciona intestinalis	59.85	0.00e+00	2438.00
IUUC-Csv-026014	Ciona savignyi	60.19	0.00e+00	2442.00
IUUC-Dno-029982	Dasypus novemcinctus	77.29	0.00e+00	3036.00
IUUC-Eca-034161	Equus caballus	77.18	0.00e+00	3029.00
IUUC-Eeu-035180	Erinaceus europaeus	60.17	0.00e+00	1117.00
IUUC-Fca-036307	Felis catus	79.39	0.00e+00	3211.00
IUUC-Fal-037332	Ficedula albicollis	77.78	0.00e+00	3121.00
IUUC-Gmo-039057	Gadus morhua	82.54	0.00e+00	3280.00
IUUC-Gac-042555	Gasterosteus aculeatus	92.01	0.00e+00	3630.00
IUUC-Ggo-045107	Gorilla gorilla	78.88	0.00e+00	3198.00
IUUC-Hsa-046482	Homo sapiens	78.98	0.00e+00	3199.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	77.17	0.00e+00	3086.00
IUUC-Loc-052642	Lepisosteus oculatus	82.88	0.00e+00	3321.00
IUUC-Laf-053649	Loxodonta africana	77.06	0.00e+00	3100.00
IUUC-Meu-056618	Macropus eugenii	65.63	0.00e+00	1535.00
IUUC-Mga-059202	Meleagris gallopavo	77.73	0.00e+00	3046.00
IUUC-Mmr-060729	Microcebus murinus	77.17	0.00e+00	3171.00
IUUC-Mdo-062462	Monodelphis domestica	78.33	0.00e+00	3099.00
IUUC-Mmu-063865	Mus musculus	78.47	0.00e+00	3209.00
IUUC-Mpu-066724	Mustela putorius furo	79.18	0.00e+00	3205.00
IUUC-Mlu-067816	Myotis lucifugus	78.50	0.00e+00	3184.00
IUUC-Opr-070213	Ochotona princeps	75.70	0.00e+00	1662.00
IUUC-Ont-071928	Oreochromis niloticus	76.97	0.00e+00	3115.00
IUUC-Oan-073563	Ornithorhynchus anatinus	78.99	0.00e+00	3195.00
IUUC-Ocu-074531	Oryctolagus cuniculus	78.88	0.00e+00	3198.00
IUUC-Ola-086943	Oryzias latipes	76.30	0.00e+00	3028.00
IUUC-Oga-088665	Otolemur garnettii	77.80	0.00e+00	3051.00
IUUC-Oar-090429	Ovis aries	78.83	0.00e+00	3194.00
IUUC-Psi-093281	Pelodiscus sinensis	77.54	0.00e+00	3137.00
IUUC-Pma-094424	Petromyzon marinus	69.20	9.00e-118	416.00
IUUC-Pfo-096150	Poecilia formosa	90.40	0.00e+00	3466.00
IUUC-Pca-100177	Procavia capensis	69.71	0.00e+00	1253.00
IUUC-Rno-105002	Rattus norvegicus	78.62	0.00e+00	3190.00
IUUC-Sha-107105	Sarcophilus harrisii	76.38	0.00e+00	2992.00
IUUC-Ssc-116282	Sus scrofa	78.91	0.00e+00	3106.00
IUUC-Tgu-116807	Taeniopygia guttata	78.52	0.00e+00	3167.00
IUUC-Tni-120118	Tetraodon nigroviridis	91.12	0.00e+00	3622.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence