iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069779

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01036423

Gene Name

PML

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000014321.2	ENSNLET00000018339.1	ENSNLEP00000017469.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.73	0.00e+00	1536.00	IUUC-Hsa-045861
E3 activity/RING/RING	68.27	0.00e+00	1036.00	IUUC-Mmu-063118

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MEPAPARSPR PQQDPARPHA PTMPPPETPS EGRQPSPSPS PTEQAPPSEE EFQFLRCQQC 60
QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR 120

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Nucleotide Sequence
(Fasta)

CTCTCCAGAG GCGGGCCCTG AGCCGGCACC TCCCCTTTCG GACAGCTCAA GGGGCTCAGC 60
CAACTGGCTC ACGCCTCCCC TTCAGCTTAT CTTCACGCCC TCCAAGATCT AAACCGAGAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000784--C:nuclear chromosome, telomeric region
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0045087--P:innate immune response
GO:0051457--P:maintenance of protein location in nucleus
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0032206--P:positive regulation of telomere maintenance
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:2000779--P:regulation of double-strand break repair
GO:0034097--P:response to cytokine
GO:0001666--P:response to hypoxia

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001901	Ailuropoda melanoleuca	78.91	0.00e+00	1225.00
IUUC-Bta-012427	Bos taurus	75.03	0.00e+00	1232.00
IUUC-Cja-019029	Callithrix jacchus	92.40	0.00e+00	1462.00
IUUC-Cfa-021127	Canis familiaris	76.62	0.00e+00	1219.00
IUUC-Cpo-022553	Cavia porcellus	71.19	0.00e+00	1072.00
IUUC-Csa-023187	Chlorocebus sabaeus	95.45	0.00e+00	1051.00
IUUC-Cho-024937	Choloepus hoffmanni	72.28	1.00e-106	380.00
IUUC-Dno-029326	Dasypus novemcinctus	78.27	0.00e+00	1183.00
IUUC-Dor-030808	Dipodomys ordii	63.13	0.00e+00	748.00
IUUC-Ete-032746	Echinops telfairi	55.20	0.00e+00	636.00
IUUC-Eca-033234	Equus caballus	80.70	0.00e+00	1238.00
IUUC-Fca-035648	Felis catus	81.95	0.00e+00	1305.00
IUUC-Ggo-044927	Gorilla gorilla	97.73	0.00e+00	1619.00
IUUC-Hsa-045861	Homo sapiens	97.73	0.00e+00	1618.00
IUUC-Itr-047861	Ictidomys tridecemlineatus	82.73	0.00e+00	1355.00
IUUC-Loc-052276	Lepisosteus oculatus	35.22	1.00e-53	204.00
IUUC-Laf-054059	Loxodonta africana	76.75	0.00e+00	1195.00
IUUC-Meu-056495	Macropus eugenii	55.27	6.00e-107	381.00
IUUC-Mga-059224	Meleagris gallopavo	46.50	9.00e-48	185.00
IUUC-Mmr-061507	Microcebus murinus	80.05	0.00e+00	1269.00
IUUC-Mdo-062196	Monodelphis domestica	46.46	0.00e+00	657.00
IUUC-Mmu-063118	Mus musculus	69.18	0.00e+00	1128.00
IUUC-Mpu-066024	Mustela putorius furo	73.70	0.00e+00	1165.00
IUUC-Mlu-066980	Myotis lucifugus	77.93	0.00e+00	1190.00
IUUC-Ocu-074016	Oryctolagus cuniculus	66.29	0.00e+00	1052.00
IUUC-Oga-089085	Otolemur garnettii	71.22	0.00e+00	1143.00
IUUC-Oar-089980	Ovis aries	72.64	0.00e+00	1163.00
IUUC-Ptr-091681	Pan troglodytes	97.62	0.00e+00	1616.00
IUUC-Pan-091965	Papio anubis	94.44	0.00e+00	1484.00
IUUC-Psi-093577	Pelodiscus sinensis	38.35	4.00e-127	449.00
IUUC-Pab-098215	Pongo abelii	93.60	0.00e+00	813.00
IUUC-Pca-100883	Procavia capensis	71.62	0.00e+00	850.00
IUUC-Pva-102465	Pteropus vampyrus	74.80	0.00e+00	840.00
IUUC-Rno-105120	Rattus norvegicus	69.27	0.00e+00	1162.00
IUUC-Sar-113320	Sorex araneus	61.87	1.00e-89	324.00
IUUC-Ssc-116042	Sus scrofa	76.58	0.00e+00	1239.00
IUUC-Tbe-127880	Tupaia belangeri	69.39	0.00e+00	919.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence