iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088948

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03184097

Gene Name

TRIM11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000009216.2	ENSOGAT00000009218.2	ENSOGAP00000008256.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.00e-08	34.1	16	57
E3 activity/RING/U-box	2.90e-06	27.3	12	71

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           CaiCl+ f d p+ ++CgH f+++C+  +w     +  +   CP Cr
   Q: 16   CAICLDYFTD-PVMTDCGHNFCRECIrRCW----GQPEGPYACPECR 57
           **********.999************99**....66789999****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl..asggk..tcPvtrqplteedlvPnltl 61
           ee  C+I l+ ++dPv++ +G+ + r++I+++    +      cP +r+   +++l Pn  l
   Q: 12   EEATCAICLDYFTDPVMTDCGHNFCRECIRRCWgqPE--GpyACPECRELSPQRNLRPNRPL 71
           7889***************************995333..346*****************866 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAAPDLSTNL QEEATCAICL DYFTDPVMTD CGHNFCRECI RRCWGQPEGP YACPECRELS 60
PQRNLRPNRP LAKMAEMARL LHPPSPVPQG VCAAHREPLA AFCGEELRLL CAACERSGEH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCCC CCGACCTGTC CACTAACCTC CAGGAGGAGG CCACCTGTGC CATCTGCCTC 60
GACTACTTCA CTGACCCAGT GATGACGGAC TGCGGTCACA ACTTCTGCCG CGAGTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0050768--P:negative regulation of neurogenesis
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0046598--P:positive regulation of viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001800	Ailuropoda melanoleuca	68.66	1.00e-162	566.00
IUUC-Bta-012332	Bos taurus	85.06	0.00e+00	754.00
IUUC-Cel-018124	Caenorhabditis elegans	21.50	2.00e-11	62.80
IUUC-Cja-019969	Callithrix jacchus	76.97	0.00e+00	644.00
IUUC-Cfa-020491	Canis familiaris	85.48	0.00e+00	766.00
IUUC-Cpo-021936	Cavia porcellus	85.89	0.00e+00	749.00
IUUC-Csa-024151	Chlorocebus sabaeus	89.00	0.00e+00	730.00
IUUC-Cho-024990	Choloepus hoffmanni	79.37	5.00e-116	410.00
IUUC-Dno-029580	Dasypus novemcinctus	78.47	0.00e+00	634.00
IUUC-Ete-032556	Echinops telfairi	65.80	1.00e-111	395.00
IUUC-Eca-033612	Equus caballus	69.27	1.00e-130	459.00
IUUC-Fca-035821	Felis catus	81.50	4.00e-141	493.00
IUUC-Ggo-044629	Gorilla gorilla	89.21	0.00e+00	733.00
IUUC-Hsa-046332	Homo sapiens	89.21	0.00e+00	732.00
IUUC-Itr-047946	Ictidomys tridecemlineatus	89.00	0.00e+00	751.00
IUUC-Laf-054350	Loxodonta africana	70.32	9.00e-142	496.00
IUUC-Mcc-055827	Macaca mulatta	87.55	0.00e+00	712.00
IUUC-Meu-056122	Macropus eugenii	69.71	0.00e+00	634.00
IUUC-Mmr-061700	Microcebus murinus	88.59	0.00e+00	751.00
IUUC-Mdo-062921	Monodelphis domestica	60.74	9.00e-161	559.00
IUUC-Mmu-063762	Mus musculus	84.75	0.00e+00	711.00
IUUC-Mpu-065873	Mustela putorius furo	85.48	0.00e+00	767.00
IUUC-Mlu-067379	Myotis lucifugus	67.41	8.00e-167	580.00
IUUC-Nle-069440	Nomascus leucogenys	88.68	0.00e+00	730.00
IUUC-Opr-070901	Ochotona princeps	76.91	2.00e-173	602.00
IUUC-Oan-073401	Ornithorhynchus anatinus	44.23	7.00e-90	324.00
IUUC-Ocu-074038	Oryctolagus cuniculus	70.41	7.00e-158	550.00
IUUC-Oar-090242	Ovis aries	78.46	0.00e+00	704.00
IUUC-Ptr-090615	Pan troglodytes	92.05	2.00e-95	342.00
IUUC-Pan-092626	Papio anubis	89.00	0.00e+00	731.00
IUUC-Pab-097895	Pongo abelii	83.20	0.00e+00	734.00
IUUC-Pca-100435	Procavia capensis	85.06	0.00e+00	729.00
IUUC-Pva-102288	Pteropus vampyrus	73.03	2.00e-176	612.00
IUUC-Pgr-103696	Puccinia graminis	34.78	5.00e-06	44.70
IUUC-Rno-105938	Rattus norvegicus	84.97	0.00e+00	718.00
IUUC-Sha-107354	Sarcophilus harrisii	72.41	0.00e+00	656.00
IUUC-Smo-108838	Selaginella moellendorffii	44.68	1.00e-07	52.80
IUUC-Tbe-127733	Tupaia belangeri	89.44	0.00e+00	756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence