iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054626

UUCD1 version

UUC-MaM-00671

Ensembl Protein ID

ENSMMUP00000026293.2

UniProt Accession

F7FNH4; F7FNH4_MACMU

Genbank Protein ID

AFE64011.1; EHH26576.1

Protein Name

Ectoderm-neural cortex protein 1

Genbank Nucleotide ID

JSUE03036218; CM001258

Gene Name

ENC1; EGK_16585

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000019996.3	ENSMMUT00000028103.3	ENSMMUP00000026293.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.10e-20	73.0	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.40e-08	32.1	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l+ g++ f++h++vLaa+S++F+a+f+++l+es+  ++v+++  + pev++ ll++ Y++++ +ne
   Q: 46   TDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQ-DSEVNFDNsIHPEVLELLLDYAYSSRVIINE 114
           7************************************9.*******77******************9987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclg+l ++d+++c++L++   +++l++F+
   Q: 146  PTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQ 177
           78*****************************6 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSVSVHENRK SRASSGSINI YLFHKSSYAD SVLTHLNLLR QQRLFTDVLL HAGNRTFPCH 60
RAVLAACSRY FEAMFSGGLK ESQDSEVNFD NSIHPEVLEL LLDYAYSSRV IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGCAGCCG GAGAGGAGGC GGTGCGGCGG TGGCGCTTCG GAGACCGGGT CCAGACGCCT 60
GGCGGCAGCC GGCGCACAAG GCGCTTTCTA GCTCCCTCCC CCGAGCACAC AGCCCGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR030562--ENC1
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0017148--P:negative regulation of translation
GO:0007399--P:nervous system development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

mcc:704577

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001434	Ailuropoda melanoleuca	100.00	0.00e+00	1194.00
IUUC-Apl-004096	Anas platyrhynchos	97.28	0.00e+00	1169.00
IUUC-Aca-004884	Anolis carolinensis	96.60	0.00e+00	1157.00
IUUC-Ame-011321	Astyanax mexicanus	88.62	0.00e+00	1112.00
IUUC-Bta-013178	Bos taurus	99.83	0.00e+00	1194.00
IUUC-Cja-019494	Callithrix jacchus	100.00	0.00e+00	1194.00
IUUC-Cfa-020824	Canis familiaris	100.00	0.00e+00	1194.00
IUUC-Cpo-021874	Cavia porcellus	99.66	0.00e+00	1191.00
IUUC-Csa-023075	Chlorocebus sabaeus	100.00	0.00e+00	1194.00
IUUC-Cho-024542	Choloepus hoffmanni	99.32	0.00e+00	1189.00
IUUC-Dre-028448	Danio rerio	88.79	0.00e+00	1118.00
IUUC-Dno-029952	Dasypus novemcinctus	99.66	0.00e+00	1191.00
IUUC-Dor-030844	Dipodomys ordii	100.00	0.00e+00	1194.00
IUUC-Ete-032817	Echinops telfairi	91.85	0.00e+00	1091.00
IUUC-Eca-033651	Equus caballus	100.00	0.00e+00	1194.00
IUUC-Fca-036541	Felis catus	100.00	0.00e+00	1194.00
IUUC-Fal-036968	Ficedula albicollis	97.28	0.00e+00	1167.00
IUUC-Gmo-038821	Gadus morhua	88.12	0.00e+00	1102.00
IUUC-Gga-040468	Gallus gallus	97.28	0.00e+00	1169.00
IUUC-Gac-041686	Gasterosteus aculeatus	89.30	0.00e+00	1115.00
IUUC-Ggo-044621	Gorilla gorilla	100.00	0.00e+00	1194.00
IUUC-Hsa-046983	Homo sapiens	99.83	0.00e+00	1192.00
IUUC-Itr-048320	Ictidomys tridecemlineatus	99.83	0.00e+00	1194.00
IUUC-Lch-049735	Latimeria chalumnae	92.70	0.00e+00	1107.00
IUUC-Loc-052350	Lepisosteus oculatus	92.02	0.00e+00	1143.00
IUUC-Laf-054117	Loxodonta africana	99.32	0.00e+00	1188.00
IUUC-Meu-056763	Macropus eugenii	98.64	0.00e+00	1180.00
IUUC-Mmr-060579	Microcebus murinus	100.00	0.00e+00	1194.00
IUUC-Mdo-061995	Monodelphis domestica	98.64	0.00e+00	1180.00
IUUC-Mmu-064206	Mus musculus	99.49	0.00e+00	1189.00
IUUC-Mpu-066884	Mustela putorius furo	100.00	0.00e+00	1194.00
IUUC-Mlu-067183	Myotis lucifugus	100.00	0.00e+00	1194.00
IUUC-Nle-069928	Nomascus leucogenys	100.00	0.00e+00	1194.00
IUUC-Opr-070238	Ochotona princeps	99.66	0.00e+00	1189.00
IUUC-Ont-072404	Oreochromis niloticus	89.64	0.00e+00	1120.00
IUUC-Oan-073303	Ornithorhynchus anatinus	97.96	0.00e+00	1173.00
IUUC-Ocu-074119	Oryctolagus cuniculus	99.66	0.00e+00	1191.00
IUUC-Ola-087510	Oryzias latipes	89.56	0.00e+00	1071.00
IUUC-Oga-089119	Otolemur garnettii	100.00	0.00e+00	1194.00
IUUC-Oar-090036	Ovis aries	93.04	0.00e+00	1063.00
IUUC-Ptr-091349	Pan troglodytes	100.00	0.00e+00	1194.00
IUUC-Pan-092098	Papio anubis	100.00	0.00e+00	1194.00
IUUC-Pma-094515	Petromyzon marinus	60.17	0.00e+00	676.00
IUUC-Pfo-097496	Poecilia formosa	90.15	0.00e+00	1125.00
IUUC-Pab-098388	Pongo abelii	100.00	0.00e+00	1194.00
IUUC-Pca-100511	Procavia capensis	91.17	0.00e+00	1068.00
IUUC-Pva-102964	Pteropus vampyrus	100.00	0.00e+00	1194.00
IUUC-Rno-106059	Rattus norvegicus	99.66	0.00e+00	1191.00
IUUC-Sha-106470	Sarcophilus harrisii	98.64	0.00e+00	1180.00
IUUC-Sar-113403	Sorex araneus	99.15	0.00e+00	1224.00
IUUC-Ssc-115566	Sus scrofa	100.00	0.00e+00	1194.00
IUUC-Tgu-117331	Taeniopygia guttata	97.11	0.00e+00	1166.00
IUUC-Tru-117890	Takifugu rubripes	89.13	0.00e+00	1112.00
IUUC-Tni-120381	Tetraodon nigroviridis	74.74	0.00e+00	894.00
IUUC-Xtr-131810	Xenopus tropicalis	93.55	0.00e+00	1137.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence