iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027700

Ensembl Protein ID

ENSDARP00000113465.2

UniProt Accession

F1R9N4; F1R9N4_DANRE

Genbank Protein ID

ENSDARP00000113465

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

CR391915

Gene Name

kmt2ba; mll4a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000062962.7	ENSDART00000136957.2	ENSDARP00000113465.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-16	61.6	1016	1063

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek.wiCpkCr 52
           vCl+C+++g++e  +v C+ C+e fH+ Cl +  +++++++++ w+C++C+
   Q: 1016 VCLLCASKGQHE--MVYCQMCCEPFHHFCLPPD-DRPKEENKEnWCCRRCK 1063
           8*********99..*******************.6665555555******7 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAAAGGGLAA SAVVATVNTT ATVRCRFPGR PWTARSLQRT EKRSHVGRVR AEDRKGPRPV 60
DVGATLREDP CLSRLLGLAE KHRRQREAGF CTSDEEEGDF TGFNVDGQWS LRSGKSSNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCGTAGT TGTTGTTGTG GTATGTAATA ATGGCGGCAG CAGGAGGCGG ATTAGCAGCC 60
TCGGCTGTTG TAGCGACCGT GAATACCACC GCCACCGTTC GCTGCCGTTT CCCAGGTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00856--SET
PF02008--zf-CXXC

SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011927	Astyanax mexicanus	52.74	0.00e+00	2597.00
IUUC-Cin-025724	Ciona intestinalis	54.69	7.00e-97	349.00
IUUC-Cme-027224	Cyanidioschyzon merolae	38.27	3.00e-11	64.30
IUUC-Laf-053703	Loxodonta africana	43.61	0.00e+00	803.00
IUUC-Meu-056046	Macropus eugenii	44.50	0.00e+00	811.00
IUUC-Mdo-062648	Monodelphis domestica	42.18	0.00e+00	819.00
IUUC-Mpu-066710	Mustela putorius furo	43.34	0.00e+00	805.00
IUUC-Mlu-067559	Myotis lucifugus	43.41	0.00e+00	808.00
IUUC-Oar-089447	Ovis aries	44.35	0.00e+00	822.00
IUUC-Pfo-096884	Poecilia formosa	45.81	0.00e+00	1805.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence