iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000015970.9	ENSDART00000138106.1	ENSDARP00000122900.1
ENSDARG00000015970.9	ENSDART00000008401.6	ENSDARP00000018130.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-30	104.5	181	218
UBD/Beta-Prp	4.40e-52	178.0	280	542

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 181  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGHLL 218
           8**********955599***************999887 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsv 97
           s +k++l ++++dgti  w+++  +l       + ++   ++v+ ++  fs  g +l+tgs+D++i+v+ +   +++ ++ l+ h+d+v
   Q: 280  SGNKRFLSSTGADGTICFWQWDARTLkfgqrpSKFIERPRPGVQMICssFSAGGMFLATGSTDHIIRVYYFGggQPEKISELESHTDKV 368
           67899999***************88877777555557777777755522778888**************776558899*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee.................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
            s++fs sgd++vsGs+d t+r+w+l+++ + +                   +++++  v++v++++++n +++++++ t+++W++ tg
   Q: 369  DSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSIlldmatklpgkynppplEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTG 457
           *******************************9999***************889999999****************************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           +l++ l g h+d v  l+   fds  + l s+++dg  ++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 458  NLIHVLMG-HEDEVFVLEphpFDS--RVLFSAGHDGNAIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 542
           *******9.*********877777..99******************999998875544444566667777999999999999888886 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAAERKHVAQ LKSELYFLIA RFLEAGPCQD AAETLIREVQ QKELLPKRID WTGKEHPGSY 60
ENLVKLYRHI SPDHLLQVCE RVSPLLEREV PASVPGVNSL LGTGRQSVLR TNKSCKHVVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGGCTCG AGCGACGTGC CGGGACTACT TTCAGTGTGT GTTGGGTGAA TGGAGGCGCA 60
GCTCTTCCTG GTGAACAAAC ACTGACAACT ACAGGGCAGC CCAGCGATAC CCGCTTCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.76	1.00e-61	232.00
IUUC-Aml-002299	Ailuropoda melanoleuca	78.58	0.00e+00	1297.00
IUUC-Atr-002600	Amborella trichopoda	30.59	3.00e-68	254.00
IUUC-Aca-004474	Anolis carolinensis	72.84	0.00e+00	2123.00
IUUC-Aly-006406	Arabidopsis lyrata	30.64	6.00e-69	256.00
IUUC-Bta-013125	Bos taurus	78.40	0.00e+00	1264.00
IUUC-Bdi-014797	Brachypodium distachyon	29.94	2.00e-59	225.00
IUUC-Bol-015737	Brassica oleracea	30.73	2.00e-71	265.00
IUUC-Bra-017961	Brassica rapa	30.69	5.00e-71	263.00
IUUC-Cja-018868	Callithrix jacchus	63.54	0.00e+00	2241.00
IUUC-Cfa-021179	Canis familiaris	76.86	0.00e+00	1322.00
IUUC-Cpo-022077	Cavia porcellus	62.22	0.00e+00	2071.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	33.21	6.00e-33	136.00
IUUC-Csa-023618	Chlorocebus sabaeus	78.12	0.00e+00	1380.00
IUUC-Cho-024794	Choloepus hoffmanni	77.01	0.00e+00	724.00
IUUC-Csv-025813	Ciona savignyi	45.17	0.00e+00	647.00
IUUC-Dno-030048	Dasypus novemcinctus	76.25	0.00e+00	1321.00
IUUC-Dor-030195	Dipodomys ordii	72.77	0.00e+00	1139.00
IUUC-Dme-031752	Drosophila melanogaster	51.85	0.00e+00	675.00
IUUC-Eca-034274	Equus caballus	78.40	0.00e+00	1256.00
IUUC-Eeu-034688	Erinaceus europaeus	80.30	0.00e+00	1120.00
IUUC-Fca-035451	Felis catus	78.89	0.00e+00	1286.00
IUUC-Gmo-039451	Gadus morhua	70.20	0.00e+00	741.00
IUUC-Gma-043340	Glycine max	31.23	1.00e-70	262.00
IUUC-Hsa-046757	Homo sapiens	78.01	0.00e+00	1364.00
IUUC-Hvu-047706	Hordeum vulgare	31.28	3.00e-38	152.00
IUUC-Loc-052672	Lepisosteus oculatus	74.98	0.00e+00	2340.00
IUUC-Mcc-055061	Macaca mulatta	77.66	0.00e+00	1367.00
IUUC-Mmr-060837	Microcebus murinus	76.75	0.00e+00	1311.00
IUUC-Mmu-063772	Mus musculus	78.01	0.00e+00	1369.00
IUUC-Mac-065343	Musa acuminata	30.52	6.00e-72	266.00
IUUC-Mlu-067928	Myotis lucifugus	77.66	0.00e+00	1291.00
IUUC-Nle-070094	Nomascus leucogenys	76.06	0.00e+00	1316.00
IUUC-Opr-070971	Ochotona princeps	58.37	0.00e+00	689.00
IUUC-Ont-072221	Oreochromis niloticus	83.41	0.00e+00	1427.00
IUUC-Oga-088578	Otolemur garnettii	78.12	0.00e+00	1264.00
IUUC-Oar-090247	Ovis aries	78.52	0.00e+00	1264.00
IUUC-Ptr-091266	Pan troglodytes	77.95	0.00e+00	1284.00
IUUC-Pan-092734	Papio anubis	78.24	0.00e+00	1381.00
IUUC-Pma-094427	Petromyzon marinus	64.05	2.00e-126	445.00
IUUC-Ppa-095793	Physcomitrella patens	28.99	7.00e-69	256.00
IUUC-Pfo-096191	Poecilia formosa	71.93	0.00e+00	2389.00
IUUC-Pab-098402	Pongo abelii	78.01	0.00e+00	1364.00
IUUC-Pop-099803	Populus trichocarpa	33.68	3.00e-78	287.00
IUUC-Pca-101128	Procavia capensis	83.26	0.00e+00	1234.00
IUUC-Ppe-101849	Prunus persica	31.45	2.00e-72	268.00
IUUC-Pva-103058	Pteropus vampyrus	80.34	0.00e+00	1177.00
IUUC-Rno-106013	Rattus norvegicus	76.67	0.00e+00	1241.00
IUUC-Sit-110017	Setaria italica	31.89	2.00e-53	205.00
IUUC-Sly-111348	Solanum lycopersicum	30.33	5.00e-69	257.00
IUUC-Sbi-114195	Sorghum bicolor	29.32	2.00e-56	214.00
IUUC-Tgu-116513	Taeniopygia guttata	58.81	0.00e+00	1711.00
IUUC-Tru-117625	Takifugu rubripes	70.13	0.00e+00	2357.00
IUUC-Tsy-119132	Tarsius syrichta	72.15	0.00e+00	1049.00
IUUC-Tni-120716	Tetraodon nigroviridis	68.49	0.00e+00	2350.00
IUUC-Tca-121615	Theobroma cacao	30.49	8.00e-66	246.00
IUUC-Tae-125478	Triticum aestivum	30.58	2.00e-70	261.00
IUUC-Tur-126809	Triticum urartu	30.42	4.00e-68	254.00
IUUC-Tbe-127479	Tupaia belangeri	68.48	0.00e+00	1015.00
IUUC-Ttr-128427	Tursiops truncatus	69.53	0.00e+00	1202.00
IUUC-Vvi-131362	Vitis vinifera	30.74	4.00e-73	270.00
IUUC-Xma-134120	Xiphophorus maculatus	84.03	0.00e+00	1382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence