iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090136

Ensembl Protein ID

ENSOARP00000007677.1

UniProt Accession

W5PB66; W5PB66_SHEEP

Genbank Protein ID

ENSOARP00000007677

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AMGL01072620

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007163.1	ENSOART00000007792.1	ENSOARP00000007677.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.80e-09	36.8	216	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 216  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 262
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MLGQQQQQQQ QRSSSAALLT GERSRLLTCY VQDYLECVES LPHDMQRNVS VLRELDNKYQ 60
ETLKEIDDVY EKYKKEDDSN QKKRLQQHLQ RALINSQELG DEKIQIVTQM LELVENRARQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCAGCG GCAGCGGCAG CAGCGGCAGG ATGTTAGGGC AGCAGCAGCA GCAGCAGCAG 60
CAACGCTCCT CGTCGGCCGC GCTCCTGACC GGCGAGCGGA GCCGGCTCCT CACCTGCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

KEGG

oas:101108806

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	97.78	2.00e-118	418.00
IUUC-Apl-003705	Anas platyrhynchos	87.89	5.00e-91	326.00
IUUC-Aca-004990	Anolis carolinensis	80.31	5.00e-97	347.00
IUUC-Ame-011426	Astyanax mexicanus	70.44	7.00e-84	303.00
IUUC-Bta-012721	Bos taurus	98.94	2.00e-121	428.00
IUUC-Cja-018960	Callithrix jacchus	97.73	3.00e-106	377.00
IUUC-Cfa-020869	Canis familiaris	97.41	7.00e-118	416.00
IUUC-Cpo-021414	Cavia porcellus	96.67	3.00e-117	414.00
IUUC-Csa-023304	Chlorocebus sabaeus	97.78	1.00e-109	389.00
IUUC-Dre-028562	Danio rerio	67.90	4.00e-88	317.00
IUUC-Dno-029945	Dasypus novemcinctus	97.73	1.00e-115	409.00
IUUC-Dor-030141	Dipodomys ordii	97.76	2.00e-116	411.00
IUUC-Ete-032709	Echinops telfairi	95.41	4.00e-127	446.00
IUUC-Eca-033432	Equus caballus	98.52	6.00e-119	420.00
IUUC-Eeu-035285	Erinaceus europaeus	97.56	2.00e-90	325.00
IUUC-Fca-036467	Felis catus	98.11	2.00e-115	408.00
IUUC-Fal-036700	Ficedula albicollis	86.67	3.00e-90	324.00
IUUC-Gmo-038748	Gadus morhua	62.32	8.00e-85	306.00
IUUC-Gga-040175	Gallus gallus	88.34	1.00e-91	329.00
IUUC-Gac-041403	Gasterosteus aculeatus	63.50	7.00e-89	320.00
IUUC-Hsa-045837	Homo sapiens	97.78	1.00e-109	389.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	98.52	3.00e-119	421.00
IUUC-Lch-049965	Latimeria chalumnae	80.92	2.00e-100	358.00
IUUC-Laf-053353	Loxodonta africana	96.00	4.00e-100	357.00
IUUC-Mcc-055155	Macaca mulatta	97.70	1.00e-72	265.00
IUUC-Meu-056470	Macropus eugenii	92.52	1.00e-110	392.00
IUUC-Mga-059570	Meleagris gallopavo	88.34	4.00e-91	327.00
IUUC-Mmr-061385	Microcebus murinus	98.15	3.00e-110	390.00
IUUC-Mdo-062144	Monodelphis domestica	92.58	4.00e-112	397.00
IUUC-Mmu-063215	Mus musculus	97.41	8.00e-119	419.00
IUUC-Mpu-065749	Mustela putorius furo	97.07	5.00e-99	353.00
IUUC-Nle-069968	Nomascus leucogenys	97.89	1.00e-81	295.00
IUUC-Ont-071524	Oreochromis niloticus	65.20	5.00e-86	310.00
IUUC-Ocu-074870	Oryctolagus cuniculus	97.88	4.00e-120	423.00
IUUC-Ola-087400	Oryzias latipes	87.80	7.00e-44	170.00
IUUC-Oga-088336	Otolemur garnettii	97.17	2.00e-110	391.00
IUUC-Ptr-091348	Pan troglodytes	97.89	6.00e-82	296.00
IUUC-Pan-092819	Papio anubis	97.78	1.00e-109	389.00
IUUC-Pfo-096633	Poecilia formosa	65.57	1.00e-79	289.00
IUUC-Pab-098346	Pongo abelii	97.41	3.00e-109	387.00
IUUC-Pca-100278	Procavia capensis	94.88	2.00e-116	410.00
IUUC-Pva-103190	Pteropus vampyrus	98.86	2.00e-116	411.00
IUUC-Rno-104940	Rattus norvegicus	97.35	7.00e-115	406.00
IUUC-Sha-107533	Sarcophilus harrisii	92.19	6.00e-113	400.00
IUUC-Sar-113630	Sorex araneus	96.10	5.00e-90	323.00
IUUC-Ssc-115734	Sus scrofa	98.86	2.00e-116	411.00
IUUC-Tgu-117034	Taeniopygia guttata	87.11	8.00e-91	326.00
IUUC-Tru-118168	Takifugu rubripes	60.58	4.00e-80	290.00
IUUC-Tsy-119494	Tarsius syrichta	98.42	1.00e-82	298.00
IUUC-Tni-120100	Tetraodon nigroviridis	61.57	6.00e-77	280.00
IUUC-Ttr-128442	Tursiops truncatus	99.02	8.00e-92	329.00
IUUC-Vpa-130063	Vicugna pacos	97.41	6.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence