iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044577

UUCD1 version

UUC-GoG-01035

Ensembl Protein ID

ENSGGOP00000014395.2

UniProt Accession

G3RFM5; G3RFM5_GORGO

Protein Name

Uncharacterized protein

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014742.2	ENSGGOT00000014807.2	ENSGGOP00000014395.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.30e-226	752.9	444	931

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g+itv+D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 444  YDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVgtskekGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 532
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +n++++++ah +++++++e+i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 533  INSQIKIDAHLNKVCPTTETIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 621
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+k++s +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 622  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 709
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ di+ k++s fw+                                                         +f++
   Q: 710  KYFNHKALQLLHCFPLDIRLKDGSLFWQspkrppspikfdlneplhlsflqnaaklyatvycipfteedlsadallnilsevkiqEFKP 798
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+ +v  +s++     ++l++++l++ ++k+++++++lsfekddd+  ++d++taa+nlra++++iep +d++++k+
   Q: 799  SNKVVQTDETARKPDHVPISSEDernaiFQLEKAILSNEATKSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYSIEP-ADRFKTKR 886
           ******************999999********************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           +ag+iipaiatt+a+v+Gl+a+E+iKv+ g +fe++kn+fl++a+
   Q: 887  VAGKIIPAIATTTATVSGLVALEMIKVTGGyPFEAYKNCFLNLAI 931
           *****************************************9886 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MEGSEPVAAH QGEEASCSSW GTGSTNKNLP IMSTASVEID DALYSRQRYV LGDTAMQKMA 60
KSHVFLSGMG GLGLEIAKNL VLAGIKKAVT IHDTEKCQAW DLGTNFFLSE DDVVNKRNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCCCGCCC CCTTCCTACC TTCCAGTAGC CGGCGGCGGT GTCTCAGGCG GCAATGGAAG 60
GATCCGAGCC TGTGGCCGCC CATCAAGGGG AAGAGGCGTC CTGTTCTTCC TGGGGGACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	92.59	0.00e+00	2036.00
IUUC-Apl-004158	Anas platyrhynchos	79.92	0.00e+00	1734.00
IUUC-Aca-005349	Anolis carolinensis	80.23	0.00e+00	1759.00
IUUC-Bta-012696	Bos taurus	92.12	0.00e+00	2031.00
IUUC-Cja-019563	Callithrix jacchus	97.15	0.00e+00	2097.00
IUUC-Cfa-020951	Canis familiaris	92.21	0.00e+00	2034.00
IUUC-Cpo-022307	Cavia porcellus	88.26	0.00e+00	1924.00
IUUC-Csa-023647	Chlorocebus sabaeus	98.39	0.00e+00	2131.00
IUUC-Cho-024682	Choloepus hoffmanni	76.95	0.00e+00	937.00
IUUC-Dre-028022	Danio rerio	66.47	0.00e+00	1463.00
IUUC-Dno-029796	Dasypus novemcinctus	90.57	0.00e+00	1945.00
IUUC-Dor-030981	Dipodomys ordii	75.82	0.00e+00	1514.00
IUUC-Ete-032514	Echinops telfairi	77.87	0.00e+00	1147.00
IUUC-Eca-033697	Equus caballus	92.62	0.00e+00	2000.00
IUUC-Eeu-035323	Erinaceus europaeus	84.43	0.00e+00	1366.00
IUUC-Fca-035858	Felis catus	93.59	0.00e+00	2019.00
IUUC-Fal-036848	Ficedula albicollis	80.14	0.00e+00	1730.00
IUUC-Gmo-039326	Gadus morhua	65.89	0.00e+00	1379.00
IUUC-Gga-040747	Gallus gallus	80.23	0.00e+00	1718.00
IUUC-Gac-041406	Gasterosteus aculeatus	66.67	0.00e+00	1385.00
IUUC-Hsa-046007	Homo sapiens	99.43	0.00e+00	2149.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	95.69	0.00e+00	1075.00
IUUC-Lch-049992	Latimeria chalumnae	73.20	0.00e+00	1540.00
IUUC-Loc-051899	Lepisosteus oculatus	68.16	0.00e+00	1481.00
IUUC-Laf-054413	Loxodonta africana	91.91	0.00e+00	1869.00
IUUC-Mcc-054656	Macaca mulatta	98.58	0.00e+00	2133.00
IUUC-Meu-056463	Macropus eugenii	71.44	0.00e+00	1422.00
IUUC-Mga-059721	Meleagris gallopavo	78.46	0.00e+00	1625.00
IUUC-Mmr-060908	Microcebus murinus	91.36	0.00e+00	2001.00
IUUC-Mdo-062096	Monodelphis domestica	84.12	0.00e+00	1890.00
IUUC-Mmu-064114	Mus musculus	88.98	0.00e+00	1952.00
IUUC-Mpu-066017	Mustela putorius furo	92.40	0.00e+00	2043.00
IUUC-Mlu-068037	Myotis lucifugus	89.99	0.00e+00	1958.00
IUUC-Nle-069494	Nomascus leucogenys	98.29	0.00e+00	2130.00
IUUC-Opr-070910	Ochotona princeps	66.74	6.00e-173	601.00
IUUC-Ont-071592	Oreochromis niloticus	68.30	0.00e+00	1447.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.30	0.00e+00	1606.00
IUUC-Ocu-074296	Oryctolagus cuniculus	93.07	0.00e+00	2035.00
IUUC-Ola-086376	Oryzias latipes	68.00	0.00e+00	1396.00
IUUC-Oga-088186	Otolemur garnettii	93.45	0.00e+00	2040.00
IUUC-Oar-089307	Ovis aries	92.21	0.00e+00	2031.00
IUUC-Ptr-090609	Pan troglodytes	99.53	0.00e+00	2148.00
IUUC-Pan-092905	Papio anubis	98.32	0.00e+00	2033.00
IUUC-Psi-093489	Pelodiscus sinensis	81.47	0.00e+00	1749.00
IUUC-Pma-094203	Petromyzon marinus	64.86	1.00e-56	211.00
IUUC-Pfo-096670	Poecilia formosa	68.52	0.00e+00	1453.00
IUUC-Pab-098418	Pongo abelii	98.58	0.00e+00	2130.00
IUUC-Pca-100889	Procavia capensis	75.31	0.00e+00	1587.00
IUUC-Pva-103144	Pteropus vampyrus	81.86	0.00e+00	1760.00
IUUC-Rno-105612	Rattus norvegicus	89.27	0.00e+00	1957.00
IUUC-Sha-107388	Sarcophilus harrisii	86.04	0.00e+00	1874.00
IUUC-Sar-113128	Sorex araneus	88.52	0.00e+00	1925.00
IUUC-Ssc-116117	Sus scrofa	92.88	0.00e+00	2049.00
IUUC-Tgu-116565	Taeniopygia guttata	80.55	0.00e+00	1741.00
IUUC-Tru-118591	Takifugu rubripes	66.70	0.00e+00	1409.00
IUUC-Tsy-119436	Tarsius syrichta	82.24	0.00e+00	1759.00
IUUC-Tni-120880	Tetraodon nigroviridis	66.28	0.00e+00	1397.00
IUUC-Tbe-127714	Tupaia belangeri	79.89	0.00e+00	1413.00
IUUC-Ttr-129159	Tursiops truncatus	80.34	0.00e+00	1708.00
IUUC-Vpa-130716	Vicugna pacos	89.98	0.00e+00	1891.00
IUUC-Xtr-132947	Xenopus tropicalis	70.27	0.00e+00	1528.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence