iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000007598.3	ENSMMUT00000040507.2	ENSMMUP00000033565.2
ENSMMUG00000007598.3	ENSMMUT00000010634.3	ENSMMUP00000009978.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.80e-09	37.4	20	53
E3 activity/RING/U-box	9.60e-06	26.7	16	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglkns 35
           CaiCl+ fkd p++ +CgH f++ C+ q w g+k++
   Q: 20   CAICLDYFKD-PVSISCGHNFCRGCVtQLW-GKKDE 53
           **********.**************99999.55554 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIek 34
           ee +C+I l+ ++dPv +++G+ + r ++ +
   Q: 16   EEAVCAICLDYFKDPVSISCGHNFCRGCVTQ 46
           7889*******************99988765 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAGYAPTPSP MQTLQEEAVC AICLDYFKDP VSISCGHNFC RGCVTQLWGK KDEEDQNEEE 60
DEWEEEEDGE AVGAVDGWDG SIREVLYRGN ADEELFQDQE DGELWLGDSG ITNWDNVDHM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGTT ATGCCCCTAC TCCCAGCCCC ATGCAGACCC TTCAGGAGGA AGCGGTGTGT 60
GCCATCTGCT TGGATTACTT CAAGGACCCC GTGTCCATCA GCTGTGGGCA CAACTTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013348	Bos taurus	70.70	1.00e-85	309.00
IUUC-Cfa-020624	Canis familiaris	71.17	7.00e-102	363.00
IUUC-Csa-023996	Chlorocebus sabaeus	97.04	6.00e-110	389.00
IUUC-Dno-029560	Dasypus novemcinctus	68.10	5.00e-89	320.00
IUUC-Eeu-035330	Erinaceus europaeus	59.09	1.00e-32	133.00
IUUC-Fca-035760	Felis catus	74.82	9.00e-94	336.00
IUUC-Ggo-044507	Gorilla gorilla	91.22	7.00e-113	399.00
IUUC-Hsa-046579	Homo sapiens	92.93	5.00e-117	413.00
IUUC-Oar-090240	Ovis aries	73.06	2.00e-91	328.00
IUUC-Ptr-090708	Pan troglodytes	81.14	1.00e-111	395.00
IUUC-Pan-092603	Papio anubis	96.36	2.00e-127	447.00
IUUC-Pab-097933	Pongo abelii	92.59	5.00e-103	367.00
IUUC-Ssc-116255	Sus scrofa	72.30	7.00e-93	333.00
IUUC-Ttr-128855	Tursiops truncatus	68.10	5.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence