iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	5.40e-23	81.1	467	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslka 59
           k+el++++e+LkqQv+i++eDFq+ER+dREr+neekeeL++qveklq+qv++  ++l+ 
   Q: 467  KQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLTTAQLRT 525
           699*****************************************************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEGRGPYRIY DPGGSTPLGE EVSAAFDRLV EENTRLKGKI QGIKMLGELL EESQMEASRL 60
RQKAEALVRD SELPPPPPAP SLVSFDPLAE LTGQDTKVQA HPTTTTTTTT TTTTTTIGNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTCCCAG GGGCGTGGCG TGGCCCTGGC ATTTCCTGGT ACTGGCCGGA GCTTAGGTTT 60
GGCGAGTCTG GCGTCGGGCC CTGAAGCGCT CTCGTCCTAG GGTGAGCGGG GCCGCTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR033372--TNIP1

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0009101--P:glycoprotein biosynthetic process
GO:0007159--P:leukocyte cell-cell adhesion
GO:0085032--P:modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0070373--P:negative regulation of ERK1 and ERK2 cascade
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050727--P:regulation of inflammatory response

KEGG

rno:363599

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002103	Ailuropoda melanoleuca	80.00	0.00e+00	801.00
IUUC-Apl-004176	Anas platyrhynchos	52.60	5.00e-150	524.00
IUUC-Aca-004362	Anolis carolinensis	54.91	2.00e-140	492.00
IUUC-Ame-011307	Astyanax mexicanus	40.20	1.00e-89	324.00
IUUC-Bta-012620	Bos taurus	77.80	0.00e+00	717.00
IUUC-Cja-018996	Callithrix jacchus	80.03	0.00e+00	880.00
IUUC-Cfa-020274	Canis familiaris	79.69	0.00e+00	798.00
IUUC-Cpo-021786	Cavia porcellus	78.89	0.00e+00	856.00
IUUC-Csa-023236	Chlorocebus sabaeus	78.96	0.00e+00	795.00
IUUC-Cho-024535	Choloepus hoffmanni	65.22	1.00e-95	343.00
IUUC-Cin-025355	Ciona intestinalis	30.00	1.00e-11	65.10
IUUC-Dre-028725	Danio rerio	46.96	2.00e-116	413.00
IUUC-Dno-028967	Dasypus novemcinctus	87.01	2.00e-115	408.00
IUUC-Dor-030761	Dipodomys ordii	74.83	3.00e-97	349.00
IUUC-Ete-032695	Echinops telfairi	67.28	0.00e+00	734.00
IUUC-Eca-033655	Equus caballus	78.66	0.00e+00	857.00
IUUC-Eeu-035335	Erinaceus europaeus	61.02	9.00e-94	337.00
IUUC-Fca-035597	Felis catus	81.38	0.00e+00	862.00
IUUC-Fal-037020	Ficedula albicollis	51.58	1.00e-139	489.00
IUUC-Gga-040812	Gallus gallus	52.49	1.00e-141	496.00
IUUC-Ggo-045345	Gorilla gorilla	78.96	0.00e+00	877.00
IUUC-Hsa-045785	Homo sapiens	80.03	0.00e+00	895.00
IUUC-Itr-048029	Ictidomys tridecemlineatus	79.72	0.00e+00	897.00
IUUC-Lch-049745	Latimeria chalumnae	51.93	3.00e-111	395.00
IUUC-Loc-052635	Lepisosteus oculatus	48.84	2.00e-131	462.00
IUUC-Laf-053625	Loxodonta africana	77.78	0.00e+00	789.00
IUUC-Mcc-055730	Macaca mulatta	79.42	0.00e+00	834.00
IUUC-Meu-056550	Macropus eugenii	68.41	2.00e-109	389.00
IUUC-Mpo-057394	Magnaporthe poae	34.62	1.20e-01	32.30
IUUC-Mga-059948	Meleagris gallopavo	66.34	7.00e-70	256.00
IUUC-Mmr-060900	Microcebus murinus	78.89	0.00e+00	927.00
IUUC-Mdo-061805	Monodelphis domestica	64.54	0.00e+00	716.00
IUUC-Mmu-063749	Mus musculus	92.45	0.00e+00	962.00
IUUC-Mpu-065979	Mustela putorius furo	78.96	0.00e+00	875.00
IUUC-Mlu-067100	Myotis lucifugus	77.06	0.00e+00	857.00
IUUC-Nle-069667	Nomascus leucogenys	80.34	0.00e+00	869.00
IUUC-Opr-070478	Ochotona princeps	75.23	0.00e+00	840.00
IUUC-Ont-071777	Oreochromis niloticus	46.27	6.00e-107	381.00
IUUC-Oan-073239	Ornithorhynchus anatinus	64.68	0.00e+00	700.00
IUUC-Ocu-073879	Oryctolagus cuniculus	79.08	0.00e+00	827.00
IUUC-Oga-088900	Otolemur garnettii	81.82	0.00e+00	969.00
IUUC-Oar-089444	Ovis aries	74.09	0.00e+00	760.00
IUUC-Ptr-090641	Pan troglodytes	80.03	0.00e+00	894.00
IUUC-Pan-092283	Papio anubis	79.69	0.00e+00	821.00
IUUC-Psi-092967	Pelodiscus sinensis	52.07	2.00e-148	519.00
IUUC-Pma-094726	Petromyzon marinus	37.82	1.00e-45	177.00
IUUC-Pfo-096085	Poecilia formosa	45.00	4.00e-109	388.00
IUUC-Pab-097976	Pongo abelii	75.94	0.00e+00	833.00
IUUC-Pca-100215	Procavia capensis	71.05	0.00e+00	677.00
IUUC-Pva-102258	Pteropus vampyrus	75.38	0.00e+00	800.00
IUUC-Sly-111729	Solanum lycopersicum	25.38	4.00e-03	37.40
IUUC-Stu-112653	Solanum tuberosum	26.05	4.00e-03	37.00
IUUC-Ssc-115652	Sus scrofa	76.99	0.00e+00	808.00
IUUC-Tgu-116648	Taeniopygia guttata	51.35	1.00e-126	446.00
IUUC-Tru-118455	Takifugu rubripes	48.42	2.00e-107	382.00
IUUC-Tsy-119152	Tarsius syrichta	45.71	5.00e-16	78.20
IUUC-Tbe-128129	Tupaia belangeri	66.67	1.00e-94	340.00
IUUC-Ttr-128305	Tursiops truncatus	72.27	0.00e+00	692.00
IUUC-Xtr-131842	Xenopus tropicalis	46.88	2.00e-114	405.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence