iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.70e-10	39.1	592	617

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf...sdtllvsGsdDgtikvWDl 30
           ++a+   s+t +++ + Dg+ +v+Dl
   Q: 592  DVAWapySSTVFAAVTTDGKAHVFDL 617
           799**8766****************7 PP

Organism

Rattus norvegicus

Functional Description
(View)

Part of the dynein complex of respiratory cilia.

Protein Sequence
(Fasta)

MPSKQIRKQS VILTRGARKR EEDSGTDVGE GADDWAQSKA AVRPPDQLEL TDAELKEEFT 60
RILTANNPHA PQNIVRYSFK ERTYKLIGFV NQMAIHFSQV GNLIPKDSDE GRRQHYRDEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGAGGAGC TGATGCTGTT CTACAAGGGC GCGAGGACCC ACAACGTCAG CTGTCCCTGA 60
AGAACCCTGG TGACTAGGAA CTGAAGTGGA AGAGAGTCTG CATTTCCTGT GTGTGGAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0966--Cell projection
KW-0969--Cilium
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0243--Dynein
KW-0493--Microtubule
KW-0505--Motor protein
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005929--C:cilium
GO:0005737--C:cytoplasm
GO:0030286--C:dynein complex
GO:0005874--C:microtubule
GO:0003774--F:motor activity
GO:0007368--P:determination of left/right symmetry
GO:0003351--P:epithelial cilium movement
GO:0007507--P:heart development

KEGG

rno:500442

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001508	Ailuropoda melanoleuca	87.80	0.00e+00	1129.00
IUUC-Apl-003576	Anas platyrhynchos	72.02	0.00e+00	956.00
IUUC-Aca-004263	Anolis carolinensis	72.42	0.00e+00	1011.00
IUUC-Bta-012580	Bos taurus	87.43	0.00e+00	1223.00
IUUC-Cja-018885	Callithrix jacchus	88.35	0.00e+00	1238.00
IUUC-Cfa-021154	Canis familiaris	86.51	0.00e+00	1157.00
IUUC-Cpo-022365	Cavia porcellus	87.66	0.00e+00	1216.00
IUUC-Cre-022804	Chlamydomonas reinhardtii	43.56	4.00e-152	531.00
IUUC-Csa-023890	Chlorocebus sabaeus	86.81	0.00e+00	1234.00
IUUC-Cin-025296	Ciona intestinalis	69.07	0.00e+00	748.00
IUUC-Csv-026179	Ciona savignyi	68.55	0.00e+00	748.00
IUUC-Dre-027574	Danio rerio	56.57	0.00e+00	754.00
IUUC-Dno-029648	Dasypus novemcinctus	92.27	0.00e+00	1026.00
IUUC-Dor-030738	Dipodomys ordii	87.61	0.00e+00	1213.00
IUUC-Dme-032178	Drosophila melanogaster	47.98	2.00e-145	509.00
IUUC-Ete-033096	Echinops telfairi	81.42	0.00e+00	1179.00
IUUC-Eca-033256	Equus caballus	88.07	0.00e+00	1205.00
IUUC-Fca-036388	Felis catus	87.91	0.00e+00	1165.00
IUUC-Fal-036675	Ficedula albicollis	72.02	0.00e+00	716.00
IUUC-Gmo-039187	Gadus morhua	60.73	0.00e+00	750.00
IUUC-Gga-041235	Gallus gallus	82.20	0.00e+00	743.00
IUUC-Gac-042452	Gasterosteus aculeatus	57.66	0.00e+00	788.00
IUUC-Ggo-045038	Gorilla gorilla	83.78	0.00e+00	1184.00
IUUC-Hsa-045904	Homo sapiens	84.04	0.00e+00	1188.00
IUUC-Loc-052443	Lepisosteus oculatus	68.30	0.00e+00	917.00
IUUC-Laf-053468	Loxodonta africana	88.67	0.00e+00	1243.00
IUUC-Mcc-055368	Macaca mulatta	87.64	0.00e+00	1242.00
IUUC-Meu-055996	Macropus eugenii	74.51	0.00e+00	778.00
IUUC-Mmr-061626	Microcebus murinus	87.50	0.00e+00	1231.00
IUUC-Mdo-062267	Monodelphis domestica	77.94	0.00e+00	1074.00
IUUC-Mmu-064412	Mus musculus	94.04	0.00e+00	1310.00
IUUC-Mpu-066739	Mustela putorius furo	87.11	0.00e+00	1160.00
IUUC-Mlu-068200	Myotis lucifugus	86.49	0.00e+00	1207.00
IUUC-Nle-069649	Nomascus leucogenys	84.09	0.00e+00	1191.00
IUUC-Opr-071052	Ochotona princeps	84.68	0.00e+00	1167.00
IUUC-Ont-071236	Oreochromis niloticus	62.65	0.00e+00	856.00
IUUC-Oan-072791	Ornithorhynchus anatinus	67.11	0.00e+00	902.00
IUUC-Ocu-074950	Oryctolagus cuniculus	88.78	0.00e+00	1234.00
IUUC-Oga-088139	Otolemur garnettii	86.81	0.00e+00	1219.00
IUUC-Oar-089578	Ovis aries	87.84	0.00e+00	1226.00
IUUC-Ptr-091329	Pan troglodytes	83.81	0.00e+00	1185.00
IUUC-Pan-092773	Papio anubis	88.66	0.00e+00	1238.00
IUUC-Psi-093756	Pelodiscus sinensis	71.43	0.00e+00	959.00
IUUC-Pma-094402	Petromyzon marinus	63.83	0.00e+00	717.00
IUUC-Pfo-097027	Poecilia formosa	63.09	0.00e+00	684.00
IUUC-Pab-098475	Pongo abelii	80.40	0.00e+00	1118.00
IUUC-Pca-100350	Procavia capensis	78.16	0.00e+00	1108.00
IUUC-Pva-103001	Pteropus vampyrus	87.91	0.00e+00	1198.00
IUUC-Sha-106892	Sarcophilus harrisii	79.74	0.00e+00	1084.00
IUUC-Tru-118061	Takifugu rubripes	55.78	0.00e+00	712.00
IUUC-Tbe-127275	Tupaia belangeri	79.57	0.00e+00	1128.00
IUUC-Ttr-128540	Tursiops truncatus	85.55	0.00e+00	1120.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence