iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059206

Ensembl Protein ID

ENSMGAP00000012006.2

UniProt Accession

G1NG26; G1NG26_MELGA

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011473.2	ENSMGAT00000012892.2	ENSMGAP00000012006.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	46.82	4.00e-118	422.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	41.31	1.00e-99	358.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

VGEHQLTGHK VAVKILNRQK IRSLDVVGKI KREIQNLKLF RHPHIIKLYQ VISTPTDFFM 60
VMEYVSGGEL FDYICKHGRV EEAEARRLFQ QILSAVDYCH RHMVVHRDLK PENVLLDAHM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGCGAAC ACCAGTTGAC GGGGCACAAA GTAGCAGTAA AAATCCTAAA CAGACAGAAA 60
ATACGCAGCC TGGATGTGGT TGGGAAGATC AAACGAGAAA TTCAAAACCT AAAACTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005623--C:cell
GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0031649--P:heat generation
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:1904101--P:response to acadesine
GO:0014850--P:response to muscle activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	45.40	2.00e-116	412.00
IUUC-Aml-001907	Ailuropoda melanoleuca	74.37	0.00e+00	753.00
IUUC-Atr-002770	Amborella trichopoda	47.47	7.00e-119	420.00
IUUC-Apl-003395	Anas platyrhynchos	99.42	0.00e+00	1078.00
IUUC-Aca-004480	Anolis carolinensis	92.81	0.00e+00	976.00
IUUC-Aly-006289	Arabidopsis lyrata	46.71	2.00e-119	421.00
IUUC-Ath-007014	Arabidopsis thaliana	46.82	2.00e-119	422.00
IUUC-Ago-007957	Ashbya gossypii	42.75	6.00e-110	390.00
IUUC-Acl-008103	Aspergillus clavatus	61.96	4.00e-96	345.00
IUUC-Afl-008555	Aspergillus flavus	61.96	1.00e-96	347.00
IUUC-Afu-008949	Aspergillus fumigatus	61.96	4.00e-96	345.00
IUUC-Ani-009408	Aspergillus nidulans	62.70	2.00e-96	346.00
IUUC-Ang-009551	Aspergillus niger	61.96	5.00e-96	345.00
IUUC-Aor-010176	Aspergillus oryzae	61.96	1.00e-96	347.00
IUUC-Ate-010287	Aspergillus terreus	61.96	6.00e-96	345.00
IUUC-Ame-011019	Astyanax mexicanus	87.52	0.00e+00	954.00
IUUC-Bgr-012045	Blumeria graminis	60.08	4.00e-95	342.00
IUUC-Bta-012786	Bos taurus	74.62	0.00e+00	754.00
IUUC-Bci-013774	Botrytis cinerea	61.57	2.00e-97	349.00
IUUC-Bdi-014319	Brachypodium distachyon	45.70	2.00e-116	412.00
IUUC-Bol-016242	Brassica oleracea	47.11	6.00e-122	430.00
IUUC-Bra-016750	Brassica rapa	47.11	5.00e-122	430.00
IUUC-Cel-018518	Caenorhabditis elegans	58.78	1.00e-170	592.00
IUUC-Cja-019386	Callithrix jacchus	91.75	0.00e+00	995.00
IUUC-Cfa-020177	Canis familiaris	74.52	0.00e+00	759.00
IUUC-Cpo-021805	Cavia porcellus	91.36	0.00e+00	989.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.30	3.00e-88	318.00
IUUC-Csa-024267	Chlorocebus sabaeus	91.36	0.00e+00	989.00
IUUC-Cho-024859	Choloepus hoffmanni	72.39	0.00e+00	746.00
IUUC-Cin-025550	Ciona intestinalis	59.00	1.00e-180	625.00
IUUC-Csv-026139	Ciona savignyi	58.59	0.00e+00	630.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	43.21	2.00e-57	216.00
IUUC-Cne-027044	Cryptococcus neoformans	51.08	1.00e-100	360.00
IUUC-Cme-027289	Cyanidioschyzon merolae	43.42	2.00e-102	366.00
IUUC-Dre-027749	Danio rerio	69.96	0.00e+00	736.00
IUUC-Dno-030006	Dasypus novemcinctus	74.37	0.00e+00	752.00
IUUC-Dor-030578	Dipodomys ordii	91.17	0.00e+00	991.00
IUUC-Dse-031507	Dothistroma septosporum	63.93	5.00e-97	348.00
IUUC-Dme-031704	Drosophila melanogaster	58.09	0.00e+00	640.00
IUUC-Ete-033055	Echinops telfairi	72.15	0.00e+00	773.00
IUUC-Eca-034016	Equus caballus	91.75	0.00e+00	997.00
IUUC-Eeu-034949	Erinaceus europaeus	48.02	7.00e-69	254.00
IUUC-Fca-035754	Felis catus	72.42	0.00e+00	749.00
IUUC-Fal-037363	Ficedula albicollis	74.95	0.00e+00	753.00
IUUC-Fox-038073	Fusarium oxysporum	52.55	5.00e-98	351.00
IUUC-Fso-038236	Fusarium solani	52.41	6.00e-95	341.00
IUUC-Gmo-039633	Gadus morhua	69.85	0.00e+00	762.00
IUUC-Ggr-039987	Gaeumannomyces graminis	49.42	8.00e-96	344.00
IUUC-Gga-040546	Gallus gallus	99.62	0.00e+00	1055.00
IUUC-Gac-041822	Gasterosteus aculeatus	83.78	0.00e+00	897.00
IUUC-Gma-042712	Glycine max	46.09	8.00e-119	420.00
IUUC-Ggo-045303	Gorilla gorilla	91.55	0.00e+00	994.00
IUUC-Hsa-045746	Homo sapiens	91.55	0.00e+00	994.00
IUUC-Hvu-047406	Hordeum vulgare	45.49	7.00e-118	417.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	91.36	0.00e+00	991.00
IUUC-Kpa-049190	Komagataella pastoris	45.89	6.00e-114	404.00
IUUC-Lch-049623	Latimeria chalumnae	74.09	0.00e+00	746.00
IUUC-Lpe-051392	Leersia perrieri	45.74	2.00e-116	412.00
IUUC-Loc-052928	Lepisosteus oculatus	91.17	0.00e+00	968.00
IUUC-Lma-053054	Leptosphaeria maculans	63.16	6.00e-98	351.00
IUUC-Laf-053459	Loxodonta africana	92.32	0.00e+00	1003.00
IUUC-Mcc-055862	Macaca mulatta	91.55	0.00e+00	994.00
IUUC-Meu-056705	Macropus eugenii	51.61	7.00e-73	268.00
IUUC-Mor-057170	Magnaporthe oryzae	51.56	3.00e-94	339.00
IUUC-Mpo-057302	Magnaporthe poae	49.56	1.00e-95	343.00
IUUC-Mtr-058309	Medicago truncatula	46.74	6.00e-117	414.00
IUUC-Mla-059058	Melampsora laricipopulina	40.37	1.00e-95	343.00
IUUC-Mvi-060337	Microbotryum violaceum	40.88	3.00e-100	358.00
IUUC-Mmr-061619	Microcebus murinus	91.36	0.00e+00	988.00
IUUC-Mdo-062160	Monodelphis domestica	91.94	0.00e+00	983.00
IUUC-Mmu-063406	Mus musculus	90.21	0.00e+00	978.00
IUUC-Mac-064518	Musa acuminata	45.14	6.00e-113	400.00
IUUC-Mpu-066326	Mustela putorius furo	92.13	0.00e+00	999.00
IUUC-Mlu-067968	Myotis lucifugus	91.40	0.00e+00	960.00
IUUC-Nfi-068493	Neosartorya fischeri	61.96	3.00e-96	345.00
IUUC-Ncr-068665	Neurospora crassa	41.68	8.00e-101	360.00
IUUC-Nle-070158	Nomascus leucogenys	91.36	0.00e+00	993.00
IUUC-Opr-070272	Ochotona princeps	72.05	0.00e+00	746.00
IUUC-Ont-071395	Oreochromis niloticus	87.21	0.00e+00	940.00
IUUC-Oan-073322	Ornithorhynchus anatinus	71.56	0.00e+00	738.00
IUUC-Ocu-074188	Oryctolagus cuniculus	72.47	0.00e+00	747.00
IUUC-Oba-075436	Oryza barthii	45.30	6.00e-117	414.00
IUUC-Obr-076507	Oryza brachyantha	46.30	1.00e-116	412.00
IUUC-Ogl-077718	Oryza glaberrima	46.20	5.00e-117	414.00
IUUC-Ogu-078349	Oryza glumaepatula	45.30	6.00e-117	414.00
IUUC-Oin-079889	Oryza indica	46.06	1.00e-117	416.00
IUUC-Olo-080521	Oryza longistaminata	45.30	7.00e-117	413.00
IUUC-Ome-081630	Oryza meridionalis	45.09	2.00e-116	412.00
IUUC-Oni-082211	Oryza nivara	45.30	3.00e-117	415.00
IUUC-Opu-083617	Oryza punctata	45.21	7.00e-117	413.00
IUUC-Oru-084252	Oryza rufipogon	45.30	7.00e-117	413.00
IUUC-Osa-085548	Oryza sativa	45.30	7.00e-117	413.00
IUUC-Ola-087169	Oryzias latipes	85.31	0.00e+00	920.00
IUUC-Olu-087861	Ostreococcus lucimarinus	42.65	2.00e-109	389.00
IUUC-Oga-088003	Otolemur garnettii	74.57	0.00e+00	754.00
IUUC-Oar-089933	Ovis aries	74.62	0.00e+00	754.00
IUUC-Ptr-090741	Pan troglodytes	91.55	0.00e+00	994.00
IUUC-Pan-092526	Papio anubis	74.57	0.00e+00	754.00
IUUC-Psi-094034	Pelodiscus sinensis	74.57	0.00e+00	753.00
IUUC-Pno-095030	Phaeosphaeria nodorum	63.16	2.00e-96	345.00
IUUC-Ppa-095615	Physcomitrella patens	49.18	4.00e-115	408.00
IUUC-Pfo-096295	Poecilia formosa	86.83	0.00e+00	934.00
IUUC-Pab-098023	Pongo abelii	91.55	0.00e+00	994.00
IUUC-Pop-100042	Populus trichocarpa	46.84	4.00e-120	424.00
IUUC-Pca-101104	Procavia capensis	77.75	1.00e-163	568.00
IUUC-Ppe-101642	Prunus persica	47.60	2.00e-117	415.00
IUUC-Pva-102470	Pteropus vampyrus	91.17	0.00e+00	983.00
IUUC-Pgr-103406	Puccinia graminis	60.82	2.00e-84	306.00
IUUC-Ptt-103713	Puccinia triticina	38.32	1.00e-76	280.00
IUUC-Pte-104259	Pyrenophora teres	63.16	1.00e-97	350.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	63.56	2.00e-98	353.00
IUUC-Rno-104960	Rattus norvegicus	91.36	0.00e+00	995.00
IUUC-Sce-106290	Saccharomyces cerevisiae	41.95	6.00e-110	390.00
IUUC-Sha-107603	Sarcophilus harrisii	74.04	0.00e+00	750.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	40.36	1.00e-103	369.00
IUUC-Spo-108202	Schizosaccharomyces pombe	41.31	4.00e-100	358.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	47.70	4.00e-97	348.00
IUUC-Smo-109309	Selaginella moellendorffii	45.59	7.00e-116	410.00
IUUC-Sit-109745	Setaria italica	46.96	6.00e-119	420.00
IUUC-Sly-110890	Solanum lycopersicum	46.47	4.00e-118	417.00
IUUC-Stu-112144	Solanum tuberosum	44.82	2.00e-111	395.00
IUUC-Sar-113521	Sorex araneus	65.33	0.00e+00	634.00
IUUC-Sbi-114764	Sorghum bicolor	46.57	7.00e-120	423.00
IUUC-Sre-115141	Sporisorium reilianum	67.34	2.00e-105	376.00
IUUC-Ssc-115732	Sus scrofa	74.52	0.00e+00	758.00
IUUC-Tgu-117190	Taeniopygia guttata	75.14	0.00e+00	752.00
IUUC-Tru-118735	Takifugu rubripes	86.26	0.00e+00	932.00
IUUC-Tsy-119503	Tarsius syrichta	88.46	0.00e+00	939.00
IUUC-Tni-119880	Tetraodon nigroviridis	86.23	0.00e+00	940.00
IUUC-Tca-121386	Theobroma cacao	46.74	5.00e-120	424.00
IUUC-Tre-122070	Trichoderma reesei	50.73	3.00e-96	345.00
IUUC-Tvi-122305	Trichoderma virens	50.59	2.00e-95	342.00
IUUC-Tae-123515	Triticum aestivum	46.79	6.00e-118	417.00
IUUC-Tur-126416	Triticum urartu	45.40	2.00e-116	412.00
IUUC-Tme-127174	Tuber melanosporum	39.89	3.00e-67	248.00
IUUC-Tbe-127791	Tupaia belangeri	86.09	4.00e-113	400.00
IUUC-Ttr-129224	Tursiops truncatus	72.42	0.00e+00	747.00
IUUC-Uma-129372	Ustilago maydis	67.34	1.00e-104	374.00
IUUC-Vda-129819	Verticillium dahliae	54.12	1.00e-78	287.00
IUUC-Vpa-130220	Vicugna pacos	91.73	0.00e+00	996.00
IUUC-Vvi-131649	Vitis vinifera	46.95	8.00e-118	416.00
IUUC-Xtr-132954	Xenopus tropicalis	92.71	0.00e+00	995.00
IUUC-Xma-134119	Xiphophorus maculatus	86.64	0.00e+00	933.00
IUUC-Yli-134422	Yarrowia lipolytica	44.97	1.00e-111	396.00
IUUC-Zma-135621	Zea mays	61.59	1.00e-111	396.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence