iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044820

UUCD1 version

UUC-GoG-01105

Ensembl Protein ID

ENSGGOP00000026122.1

UniProt Accession

G3SDE2; G3SDE2_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000009540.2	ENSGGOT00000029196.1	ENSGGOP00000026122.1
ENSGGOG00000009540.2	ENSGGOT00000009589.2	ENSGGOP00000009329.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-75	254.8	158	532

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 158  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 240
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 241  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 303
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 304  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFID 392
           54045678******************************************************************************999 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkne 302
            ++ek+ +                                                     + +YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 393  VEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegicletnsgtekisksgleknSLIYELFSVMVHSGSAAGGHYYACIKSF 481
           9777666678888888888888889999999999999999999999999999999999999***************************6 PP
   S: 303  kgk.WllfdDskVtevkeeevleetg................staYvlfYk 336
           +++ W+ f+D++V+ +++e++++++g                ++aY+l+Y+
   Q: 482  SDEqWYSFNDQHVSRITQEDIKKTHGgssgsrgyyssafassTNAYMLIYR 532
           5555*******************888************************8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

QIENAAEEPR VLCIIQDTTN SKTVNERITL NLPASTPVRK LFEDVANKVG YINGTFDLVW 60
GNGINTADMA PLDHTSDKSL LDANFEPGKK NFLHLTDKDG EQPQILLLRD GGLGRMSPKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATAGAAA ATGCTGCTGA AGAACCTAGA GTCTTATGTA TTATACAAGA TACTACTAAT 60
TCAAAGACAG TGAATGAACG GATCACTTTA AATTTACCAG CATCTACTCC AGTCAGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	94.14	0.00e+00	2440.00
IUUC-Apl-003486	Anas platyrhynchos	88.62	0.00e+00	2288.00
IUUC-Aca-005061	Anolis carolinensis	86.40	0.00e+00	2316.00
IUUC-Ame-011206	Astyanax mexicanus	78.80	0.00e+00	2034.00
IUUC-Bta-012942	Bos taurus	94.94	0.00e+00	2480.00
IUUC-Cel-018600	Caenorhabditis elegans	37.62	1.00e-122	434.00
IUUC-Cja-018950	Callithrix jacchus	96.63	0.00e+00	2353.00
IUUC-Cfa-020299	Canis familiaris	95.84	0.00e+00	2493.00
IUUC-Cpo-021943	Cavia porcellus	94.87	0.00e+00	2451.00
IUUC-Csa-023285	Chlorocebus sabaeus	96.95	0.00e+00	2501.00
IUUC-Cho-025006	Choloepus hoffmanni	91.68	0.00e+00	2049.00
IUUC-Cin-025145	Ciona intestinalis	41.54	0.00e+00	731.00
IUUC-Csv-025839	Ciona savignyi	49.62	2.00e-166	580.00
IUUC-Dre-027959	Danio rerio	79.32	0.00e+00	1977.00
IUUC-Dno-030023	Dasypus novemcinctus	92.59	0.00e+00	2337.00
IUUC-Dor-030994	Dipodomys ordii	97.72	0.00e+00	965.00
IUUC-Dme-031604	Drosophila melanogaster	49.31	3.00e-148	520.00
IUUC-Ete-032596	Echinops telfairi	81.30	0.00e+00	1311.00
IUUC-Eca-033913	Equus caballus	95.39	0.00e+00	2486.00
IUUC-Eeu-034518	Erinaceus europaeus	87.46	0.00e+00	2095.00
IUUC-Fca-035997	Felis catus	95.62	0.00e+00	2482.00
IUUC-Fal-037088	Ficedula albicollis	90.68	0.00e+00	2073.00
IUUC-Gmo-038920	Gadus morhua	75.62	0.00e+00	1919.00
IUUC-Gga-040953	Gallus gallus	87.74	0.00e+00	2281.00
IUUC-Gac-042400	Gasterosteus aculeatus	77.94	0.00e+00	1972.00
IUUC-Hsa-046634	Homo sapiens	97.10	0.00e+00	2501.00
IUUC-Lch-050440	Latimeria chalumnae	84.39	0.00e+00	2223.00
IUUC-Loc-051904	Lepisosteus oculatus	82.98	0.00e+00	2149.00
IUUC-Laf-053760	Loxodonta africana	94.28	0.00e+00	2486.00
IUUC-Mcc-054637	Macaca mulatta	97.03	0.00e+00	2502.00
IUUC-Meu-056904	Macropus eugenii	95.60	0.00e+00	1695.00
IUUC-Mga-059556	Meleagris gallopavo	87.07	0.00e+00	2260.00
IUUC-Mmr-061192	Microcebus murinus	96.28	0.00e+00	2482.00
IUUC-Mdo-061929	Monodelphis domestica	93.23	0.00e+00	2429.00
IUUC-Mmu-063726	Mus musculus	91.90	0.00e+00	2425.00
IUUC-Mpu-066014	Mustela putorius furo	95.76	0.00e+00	2490.00
IUUC-Mlu-067232	Myotis lucifugus	95.10	0.00e+00	2459.00
IUUC-Nle-069619	Nomascus leucogenys	96.95	0.00e+00	2500.00
IUUC-Opr-070224	Ochotona princeps	93.43	0.00e+00	1146.00
IUUC-Ont-071384	Oreochromis niloticus	79.21	0.00e+00	2004.00
IUUC-Oan-073208	Ornithorhynchus anatinus	86.80	0.00e+00	2308.00
IUUC-Ocu-074285	Oryctolagus cuniculus	95.84	0.00e+00	2472.00
IUUC-Ola-087051	Oryzias latipes	77.82	0.00e+00	1932.00
IUUC-Oga-088928	Otolemur garnettii	95.69	0.00e+00	2472.00
IUUC-Oar-090215	Ovis aries	95.33	0.00e+00	2488.00
IUUC-Ptr-091035	Pan troglodytes	97.03	0.00e+00	2501.00
IUUC-Pan-092377	Papio anubis	96.51	0.00e+00	2479.00
IUUC-Pfo-096722	Poecilia formosa	78.38	0.00e+00	1995.00
IUUC-Pab-098723	Pongo abelii	96.88	0.00e+00	2498.00
IUUC-Pca-100105	Procavia capensis	90.19	0.00e+00	2267.00
IUUC-Pva-102514	Pteropus vampyrus	90.71	0.00e+00	862.00
IUUC-Rno-105384	Rattus norvegicus	93.16	0.00e+00	2414.00
IUUC-Sha-106982	Sarcophilus harrisii	91.00	0.00e+00	2427.00
IUUC-Sar-113723	Sorex araneus	86.90	0.00e+00	933.00
IUUC-Ssc-115671	Sus scrofa	97.97	0.00e+00	2049.00
IUUC-Tgu-116722	Taeniopygia guttata	86.71	0.00e+00	2248.00
IUUC-Tru-118380	Takifugu rubripes	76.40	0.00e+00	1994.00
IUUC-Tsy-119646	Tarsius syrichta	89.22	0.00e+00	2258.00
IUUC-Tni-120762	Tetraodon nigroviridis	76.61	0.00e+00	2012.00
IUUC-Tbe-127861	Tupaia belangeri	93.20	0.00e+00	2316.00
IUUC-Ttr-129254	Tursiops truncatus	88.10	0.00e+00	1406.00
IUUC-Vpa-130141	Vicugna pacos	91.76	0.00e+00	1139.00
IUUC-Xtr-132700	Xenopus tropicalis	79.96	0.00e+00	2128.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence