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Tag Content
iUUCD ID IUUC-Oar-089751
Ensembl Protein ID ENSOARP00000012000.1
UniProt Accession W5PNH4; W5PNH4_SHEEP
Genbank Protein ID ENSOARP00000012000
Protein Name Autophagy protein 5
Genbank Nucleotide ID AMGL01106587
Gene Name ATG5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOARG00000011199.1 ENSOART00000012175.1 ENSOARP00000012000.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/Other 23.99 3.00e-08 53.90 IUUC-Sce-106216
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Ovis aries
Functional Description
(View)

Functional Description



     Involved in autophagic vesicle formation.
Involved in autophagic vesicle formation.
Protein Sequence
(Fasta)
MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM 60
RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDV 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Oar-089751|E3,Cullin RING/Other|Ovis aries
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAGACAAAG GTATATACAA TTGGATGGAT GGAGGGCTTC AGTATTCAGG TATTTTATTG 60
TTAAATAACT GTTAATTCAT GCTGTGGCTC TGACAAAGTG AAGATGAGAA AACAGATATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Oar-089751|E3,Cullin RING/Other|Ovis aries
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0001974--P:blood vessel remodeling
GO:0019725--P:cellular homeostasis
GO:0071500--P:cellular response to nitrosative stress
GO:0009267--P:cellular response to starvation
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000583 Aegilops tauschii 32.35 2.00e-24 108.00
IUUC-Aml-002403 Ailuropoda melanoleuca 97.83 3.00e-157 546.00
IUUC-Atr-002645 Amborella trichopoda 26.41 1.00e-23 103.00
IUUC-Apl-003611 Anas platyrhynchos 90.18 1.00e-153 535.00
IUUC-Aca-004411 Anolis carolinensis 89.57 2.00e-150 524.00
IUUC-Aly-005636 Arabidopsis lyrata 26.97 6.00e-27 114.00
IUUC-Ath-006959 Arabidopsis thaliana 27.58 3.00e-27 115.00
IUUC-Ago-007978 Ashbya gossypii 25.49 5.00e-07 48.10
IUUC-Acl-008328 Aspergillus clavatus 26.10 6.00e-20 91.30
IUUC-Afl-008638 Aspergillus flavus 25.56 2.00e-25 109.00
IUUC-Afu-009042 Aspergillus fumigatus 26.20 5.00e-27 114.00
IUUC-Ani-009364 Aspergillus nidulans 30.05 1.00e-23 103.00
IUUC-Aor-009889 Aspergillus oryzae 25.56 2.00e-25 109.00
IUUC-Ate-010511 Aspergillus terreus 31.18 5.00e-10 55.80
IUUC-Ame-011644 Astyanax mexicanus 86.08 9.00e-38 147.00
IUUC-Bgr-012153 Blumeria graminis 28.15 2.00e-18 85.90
IUUC-Bta-012360 Bos taurus 100.00 6.00e-88 315.00
IUUC-Bci-013723 Botrytis cinerea 26.99 8.00e-16 77.00
IUUC-Bdi-014520 Brachypodium distachyon 23.33 2.00e-22 99.80
IUUC-Bol-016053 Brassica oleracea 26.57 2.00e-29 122.00
IUUC-Bra-017072 Brassica rapa 26.95 1.00e-29 123.00
IUUC-Cel-018529 Caenorhabditis elegans 35.64 2.00e-38 152.00
IUUC-Cja-019569 Callithrix jacchus 98.55 1.00e-158 551.00
IUUC-Cfa-020473 Canis familiaris 98.55 8.00e-159 552.00
IUUC-Cpo-021421 Cavia porcellus 96.73 1.00e-156 545.00
IUUC-Cre-022862 Chlamydomonas reinhardtii 29.31 5.00e-18 84.30
IUUC-Csa-024197 Chlorocebus sabaeus 98.18 6.00e-158 549.00
IUUC-Cho-024521 Choloepus hoffmanni 95.40 2.00e-131 461.00
IUUC-Cin-025119 Ciona intestinalis 45.83 4.00e-64 237.00
IUUC-Csv-026192 Ciona savignyi 46.27 1.00e-65 242.00
IUUC-Cgl-026686 Colletotrichum gloeosporioides 23.47 6.00e-09 54.70
IUUC-Dre-028466 Danio rerio 81.82 2.00e-136 477.00
IUUC-Dse-031228 Dothistroma septosporum 26.80 8.00e-31 127.00
IUUC-Dme-031703 Drosophila melanogaster 48.71 1.00e-73 269.00
IUUC-Ete-032482 Echinops telfairi 96.23 1.00e-132 465.00
IUUC-Eca-034036 Equus caballus 97.82 3.00e-158 550.00
IUUC-Eeu-035235 Erinaceus europaeus 98.11 1.00e-86 312.00
IUUC-Fca-036263 Felis catus 98.55 1.00e-158 551.00
IUUC-Fal-037064 Ficedula albicollis 90.18 4.00e-154 536.00
IUUC-Fox-037813 Fusarium oxysporum 26.50 6.00e-17 80.90
IUUC-Fso-038139 Fusarium solani 26.67 4.00e-18 84.70
IUUC-Gmo-039509 Gadus morhua 82.43 1.00e-112 399.00
IUUC-Ggr-040111 Gaeumannomyces graminis 25.00 2.00e-13 69.70
IUUC-Gga-040517 Gallus gallus 89.45 3.00e-152 530.00
IUUC-Gac-042270 Gasterosteus aculeatus 77.73 1.00e-117 416.00
IUUC-Gma-044400 Glycine max 35.54 2.00e-23 102.00
IUUC-Ggo-045048 Gorilla gorilla 97.09 3.00e-156 543.00
IUUC-Hsa-046744 Homo sapiens 97.82 1.00e-157 548.00
IUUC-Kpa-049174 Komagataella pastoris 24.67 9.00e-14 70.90
IUUC-Lch-049475 Latimeria chalumnae 88.36 3.00e-148 517.00
IUUC-Lpe-051283 Leersia perrieri 35.46 2.00e-23 104.00
IUUC-Loc-052446 Lepisosteus oculatus 83.64 2.00e-142 498.00
IUUC-Lma-053278 Leptosphaeria maculans 27.53 6.00e-30 124.00
IUUC-Laf-054020 Loxodonta africana 97.11 2.00e-156 544.00
IUUC-Mcc-055176 Macaca mulatta 97.82 1.00e-157 548.00
IUUC-Mor-057164 Magnaporthe oryzae 25.79 1.00e-16 80.10
IUUC-Mpo-057428 Magnaporthe poae 26.27 4.00e-13 68.20
IUUC-Mtr-058424 Medicago truncatula 35.37 3.00e-23 102.00
IUUC-Mla-058872 Melampsora laricipopulina 30.07 2.00e-30 126.00
IUUC-Mga-059859 Meleagris gallopavo 89.45 3.00e-152 530.00
IUUC-Mmr-061482 Microcebus murinus 98.55 7.00e-159 552.00
IUUC-Mdo-062371 Monodelphis domestica 95.27 4.00e-160 556.00
IUUC-Mmu-063139 Mus musculus 96.00 3.00e-156 543.00
IUUC-Mac-065332 Musa acuminata 34.48 3.00e-26 112.00
IUUC-Mpu-066783 Mustela putorius furo 98.18 5.00e-158 549.00
IUUC-Mlu-068165 Myotis lucifugus 96.39 4.00e-155 540.00
IUUC-Nfi-068578 Neosartorya fischeri 27.16 5.00e-28 118.00
IUUC-Ncr-068636 Neurospora crassa 24.62 5.00e-12 65.50
IUUC-Nle-069740 Nomascus leucogenys 98.18 8.00e-158 548.00
IUUC-Opr-070802 Ochotona princeps 98.11 1.00e-85 309.00
IUUC-Ont-072222 Oreochromis niloticus 79.64 4.00e-136 476.00
IUUC-Oan-072760 Ornithorhynchus anatinus 93.91 6.00e-112 396.00
IUUC-Ocu-074844 Oryctolagus cuniculus 94.19 8.00e-97 345.00
IUUC-Oba-075834 Oryza barthii 33.33 1.00e-24 107.00
IUUC-Obr-076230 Oryza brachyantha 33.01 2.00e-14 72.80
IUUC-Ogl-077554 Oryza glaberrima 33.33 1.00e-24 107.00
IUUC-Ogu-078687 Oryza glumaepatula 33.33 7.00e-25 108.00
IUUC-Oin-079677 Oryza indica 26.10 1.00e-26 113.00
IUUC-Olo-081078 Oryza longistaminata 36.11 6.00e-25 108.00
IUUC-Ome-081548 Oryza meridionalis 33.90 2.00e-27 118.00
IUUC-Oni-082050 Oryza nivara 33.90 2.00e-25 109.00
IUUC-Opu-083609 Oryza punctata 33.71 2.00e-25 109.00
IUUC-Oru-085057 Oryza rufipogon 33.90 4.00e-25 108.00
IUUC-Osa-085917 Oryza sativa 33.90 4.00e-25 108.00
IUUC-Ola-087032 Oryzias latipes 79.64 8.00e-135 472.00
IUUC-Olu-087877 Ostreococcus lucimarinus 28.24 4.00e-03 33.90
IUUC-Oga-088468 Otolemur garnettii 97.11 3.00e-161 560.00
IUUC-Ptr-091064 Pan troglodytes 97.82 1.00e-157 548.00
IUUC-Pan-092505 Papio anubis 97.47 3.00e-156 543.00
IUUC-Psi-093086 Pelodiscus sinensis 91.30 3.00e-154 536.00
IUUC-Pno-094825 Phaeosphaeria nodorum 28.83 9.00e-27 113.00
IUUC-Ppa-095419 Physcomitrella patens 32.53 4.00e-25 108.00
IUUC-Pfo-096224 Poecilia formosa 78.55 8.00e-134 469.00
IUUC-Pab-098501 Pongo abelii 97.82 8.00e-157 545.00
IUUC-Pop-099243 Populus trichocarpa 27.96 3.00e-25 109.00
IUUC-Ppe-101255 Prunus persica 26.76 8.00e-28 117.00
IUUC-Pva-102828 Pteropus vampyrus 98.18 1.00e-157 548.00
IUUC-Pgr-103672 Puccinia graminis 30.26 4.00e-26 112.00
IUUC-Ptt-104013 Puccinia triticina 27.66 3.00e-22 99.40
IUUC-Pyt-104615 Pyrenophora triticirepentis 28.01 3.00e-28 118.00
IUUC-Rno-106089 Rattus norvegicus 93.47 6.00e-134 469.00
IUUC-Sce-106216 Saccharomyces cerevisiae 23.99 2.00e-11 62.40
IUUC-Sha-106484 Sarcophilus harrisii 94.18 2.00e-158 551.00
IUUC-Sja-107699 Schizosaccharomyces japonicus 28.20 4.00e-26 111.00
IUUC-Spo-108177 Schizosaccharomyces pombe 28.11 2.00e-22 99.00
IUUC-Ssl-108475 Sclerotinia sclerotiorum 28.03 5.00e-17 81.30
IUUC-Smo-109473 Selaginella moellendorffii 26.91 3.00e-23 102.00
IUUC-Sit-110736 Setaria italica 32.98 1.00e-28 120.00
IUUC-Sly-111657 Solanum lycopersicum 36.59 3.00e-27 115.00
IUUC-Sar-113050 Sorex araneus 82.43 2.00e-107 381.00
IUUC-Sbi-114258 Sorghum bicolor 33.33 1.00e-25 110.00
IUUC-Sre-114902 Sporisorium reilianum 31.19 8.00e-23 101.00
IUUC-Ssc-116166 Sus scrofa 92.36 1.00e-148 518.00
IUUC-Tgu-116814 Taeniopygia guttata 89.45 1.00e-152 531.00
IUUC-Tru-118172 Takifugu rubripes 80.07 2.00e-134 471.00
IUUC-Tsy-119010 Tarsius syrichta 84.00 2.00e-134 471.00
IUUC-Tni-120397 Tetraodon nigroviridis 80.00 3.00e-102 363.00
IUUC-Tca-121283 Theobroma cacao 28.21 3.00e-28 119.00
IUUC-Tvi-122545 Trichoderma virens 24.40 8.00e-15 73.90
IUUC-Tae-122685 Triticum aestivum 31.58 2.00e-24 105.00
IUUC-Tur-126407 Triticum urartu 34.23 1.00e-24 107.00
IUUC-Tme-126913 Tuber melanosporum 31.23 8.00e-40 157.00
IUUC-Tbe-127738 Tupaia belangeri 89.29 1.00e-104 371.00
IUUC-Ttr-128528 Tursiops truncatus 99.27 4.00e-159 553.00
IUUC-Uma-129625 Ustilago maydis 28.11 3.00e-20 93.20
IUUC-Vda-129906 Verticillium dahliae 23.51 2.00e-11 62.40
IUUC-Vpa-130223 Vicugna pacos 97.82 4.00e-153 533.00
IUUC-Vvi-131617 Vitis vinifera 26.61 1.00e-27 117.00
IUUC-Xtr-132288 Xenopus tropicalis 86.91 5.00e-145 506.00
IUUC-Xma-134214 Xiphophorus maculatus 81.87 2.00e-97 348.00
IUUC-Yli-134377 Yarrowia lipolytica 24.88 2.00e-12 66.20
IUUC-Zma-135108 Zea mays 34.03 2.00e-23 103.00
Created Date 25-Jun-2017

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