iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089508

Ensembl Protein ID

ENSOARP00000013395.1

UniProt Accession

W5PSG6; W5PSG6_SHEEP

Genbank Protein ID

ENSOARP00000013395

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01091635

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012501.1	ENSOART00000013592.1	ENSOARP00000013395.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	7.20e-151	501.8	175	479
E3 adaptor/Cullin RING/DCX/DWD	1.30e-26	91.7	311	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 175  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 263
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wna++lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 264  LSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 352
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 353  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 442  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
           *********************************99875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 311  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 341
           8**********98889**************9 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MDQDYERRLL RQIVIQNENT MPCVAEMRRT LTPANSPVSS PSKHGDRFIP SRAGANWSVN 60
FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAGG ACTATGAGCG GCGCCTCCTG CGGCAGATCG TCATCCAGAA CGAGAACACG 60
ATGCCGTGCG TGAGTGCTGG GGCTAGCGCG CCAGCGCCAT CCTGCCCGGT GGAGCCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

oas:101117072

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000670	Aegilops tauschii	64.19	2.00e-114	406.00
IUUC-Aml-002003	Ailuropoda melanoleuca	94.96	0.00e+00	956.00
IUUC-Atr-002753	Amborella trichopoda	57.43	1.00e-132	466.00
IUUC-Apl-003212	Anas platyrhynchos	98.58	0.00e+00	1009.00
IUUC-Aly-005442	Arabidopsis lyrata	54.55	1.00e-139	489.00
IUUC-Ath-006938	Arabidopsis thaliana	57.83	3.00e-137	481.00
IUUC-Ago-007784	Ashbya gossypii	49.42	2.00e-96	346.00
IUUC-Acl-008269	Aspergillus clavatus	49.19	2.00e-133	469.00
IUUC-Afl-008432	Aspergillus flavus	50.00	8.00e-133	467.00
IUUC-Afu-008829	Aspergillus fumigatus	50.00	2.00e-134	472.00
IUUC-Ani-009471	Aspergillus nidulans	48.89	2.00e-132	466.00
IUUC-Ang-009711	Aspergillus niger	50.41	2.00e-131	462.00
IUUC-Aor-010118	Aspergillus oryzae	50.00	8.00e-133	467.00
IUUC-Ate-010534	Aspergillus terreus	50.00	1.00e-132	466.00
IUUC-Ame-011011	Astyanax mexicanus	92.35	0.00e+00	884.00
IUUC-Bgr-012013	Blumeria graminis	49.90	9.00e-132	463.00
IUUC-Bta-012586	Bos taurus	100.00	0.00e+00	1019.00
IUUC-Bci-013807	Botrytis cinerea	51.00	2.00e-127	449.00
IUUC-Bdi-014981	Brachypodium distachyon	70.49	3.00e-129	455.00
IUUC-Bol-016301	Brassica oleracea	55.73	6.00e-139	487.00
IUUC-Bra-017453	Brassica rapa	55.73	4.00e-139	487.00
IUUC-Cel-018472	Caenorhabditis elegans	64.92	2.00e-143	503.00
IUUC-Cja-019929	Callithrix jacchus	98.59	0.00e+00	1004.00
IUUC-Cfa-020977	Canis familiaris	98.79	0.00e+00	1010.00
IUUC-Cpo-021537	Cavia porcellus	99.39	0.00e+00	1016.00
IUUC-Csa-023389	Chlorocebus sabaeus	98.99	0.00e+00	1009.00
IUUC-Cin-025327	Ciona intestinalis	68.90	0.00e+00	630.00
IUUC-Csv-025921	Ciona savignyi	66.86	0.00e+00	673.00
IUUC-Cgl-026631	Colletotrichum gloeosporioides	50.69	7.00e-133	467.00
IUUC-Cne-026933	Cryptococcus neoformans	51.03	3.00e-128	452.00
IUUC-Cme-027143	Cyanidioschyzon merolae	63.70	5.00e-118	419.00
IUUC-Dre-027470	Danio rerio	91.73	0.00e+00	881.00
IUUC-Dno-029629	Dasypus novemcinctus	90.07	0.00e+00	823.00
IUUC-Dor-030187	Dipodomys ordii	87.90	0.00e+00	876.00
IUUC-Dse-031502	Dothistroma septosporum	49.69	3.00e-127	448.00
IUUC-Dme-031858	Drosophila melanogaster	69.51	0.00e+00	686.00
IUUC-Ete-032562	Echinops telfairi	85.80	0.00e+00	853.00
IUUC-Eca-034210	Equus caballus	99.19	0.00e+00	1015.00
IUUC-Fca-035839	Felis catus	93.91	0.00e+00	939.00
IUUC-Fal-036895	Ficedula albicollis	98.38	0.00e+00	1007.00
IUUC-Fox-037814	Fusarium oxysporum	64.29	1.00e-123	435.00
IUUC-Fso-038420	Fusarium solani	49.41	1.00e-132	466.00
IUUC-Gmo-039544	Gadus morhua	89.94	0.00e+00	858.00
IUUC-Ggr-039774	Gaeumannomyces graminis	49.71	1.00e-132	466.00
IUUC-Gga-041025	Gallus gallus	98.38	0.00e+00	1007.00
IUUC-Gac-041596	Gasterosteus aculeatus	90.52	0.00e+00	869.00
IUUC-Gma-042657	Glycine max	56.63	5.00e-135	474.00
IUUC-Ggo-045599	Gorilla gorilla	98.19	0.00e+00	966.00
IUUC-Hsa-046695	Homo sapiens	98.39	0.00e+00	1003.00
IUUC-Hvu-047486	Hordeum vulgare	65.95	2.00e-106	378.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	98.17	0.00e+00	1008.00
IUUC-Kpa-049239	Komagataella pastoris	45.51	4.00e-123	435.00
IUUC-Lch-049827	Latimeria chalumnae	96.75	0.00e+00	957.00
IUUC-Lpe-051568	Leersia perrieri	50.90	2.00e-111	396.00
IUUC-Loc-052856	Lepisosteus oculatus	94.95	0.00e+00	931.00
IUUC-Laf-054321	Loxodonta africana	62.90	3.00e-156	544.00
IUUC-Mcc-055601	Macaca mulatta	98.99	0.00e+00	1009.00
IUUC-Meu-056276	Macropus eugenii	67.92	6.00e-174	603.00
IUUC-Mor-057113	Magnaporthe oryzae	49.80	3.00e-132	465.00
IUUC-Mpo-057599	Magnaporthe poae	50.00	7.00e-133	467.00
IUUC-Mtr-057689	Medicago truncatula	56.89	4.00e-137	481.00
IUUC-Mla-059048	Melampsora laricipopulina	49.90	2.00e-119	422.00
IUUC-Mga-060097	Meleagris gallopavo	92.35	0.00e+00	934.00
IUUC-Mvi-060465	Microbotryum violaceum	51.41	4.00e-131	461.00
IUUC-Mmr-061151	Microcebus murinus	89.72	0.00e+00	880.00
IUUC-Mdo-063062	Monodelphis domestica	98.17	0.00e+00	1008.00
IUUC-Mmu-063731	Mus musculus	98.99	0.00e+00	1012.00
IUUC-Mac-065208	Musa acuminata	57.70	4.00e-129	454.00
IUUC-Mpu-066173	Mustela putorius furo	98.99	0.00e+00	1012.00
IUUC-Mlu-068030	Myotis lucifugus	98.79	0.00e+00	1009.00
IUUC-Nfi-068536	Neosartorya fischeri	50.00	7.00e-135	474.00
IUUC-Ncr-068734	Neurospora crassa	52.57	4.00e-135	475.00
IUUC-Nle-070163	Nomascus leucogenys	98.99	0.00e+00	1009.00
IUUC-Opr-070974	Ochotona princeps	91.78	2.00e-155	541.00
IUUC-Ont-072507	Oreochromis niloticus	87.27	0.00e+00	898.00
IUUC-Oan-073634	Ornithorhynchus anatinus	99.66	2.00e-175	607.00
IUUC-Oba-075417	Oryza barthii	62.86	7.00e-111	394.00
IUUC-Obr-076123	Oryza brachyantha	69.51	4.00e-126	444.00
IUUC-Ogl-077294	Oryza glaberrima	53.88	4.00e-126	444.00
IUUC-Ogu-077996	Oryza glumaepatula	53.66	8.00e-125	440.00
IUUC-Oin-080172	Oryza indica	70.16	3.00e-126	444.00
IUUC-Olo-081068	Oryza longistaminata	70.16	6.00e-126	443.00
IUUC-Ome-081250	Oryza meridionalis	54.34	3.00e-127	448.00
IUUC-Oni-083048	Oryza nivara	53.88	4.00e-126	444.00
IUUC-Opu-083333	Oryza punctata	54.29	1.00e-126	446.00
IUUC-Oru-085001	Oryza rufipogon	53.88	4.00e-126	444.00
IUUC-Osa-086243	Oryza sativa	53.88	4.00e-126	444.00
IUUC-Ola-087094	Oryzias latipes	88.05	0.00e+00	827.00
IUUC-Oga-088911	Otolemur garnettii	99.59	0.00e+00	1017.00
IUUC-Ptr-090967	Pan troglodytes	86.29	0.00e+00	678.00
IUUC-Pan-092147	Papio anubis	98.39	0.00e+00	1003.00
IUUC-Psi-093702	Pelodiscus sinensis	97.78	0.00e+00	999.00
IUUC-Pma-094581	Petromyzon marinus	83.86	0.00e+00	818.00
IUUC-Pno-095139	Phaeosphaeria nodorum	59.76	6.00e-113	401.00
IUUC-Ppa-095952	Physcomitrella patens	57.17	2.00e-141	495.00
IUUC-Pfo-096309	Poecilia formosa	90.93	0.00e+00	872.00
IUUC-Pab-098762	Pongo abelii	81.25	0.00e+00	780.00
IUUC-Pop-098924	Populus trichocarpa	57.11	9.00e-133	466.00
IUUC-Pca-100565	Procavia capensis	92.81	0.00e+00	892.00
IUUC-Ppe-101924	Prunus persica	57.24	2.00e-136	479.00
IUUC-Pva-102602	Pteropus vampyrus	96.36	0.00e+00	967.00
IUUC-Pgr-103466	Puccinia graminis	51.07	1.00e-118	420.00
IUUC-Ptt-103888	Puccinia triticina	53.71	3.00e-107	382.00
IUUC-Pte-104097	Pyrenophora teres	48.86	2.00e-130	459.00
IUUC-Pyt-104445	Pyrenophora triticirepentis	44.97	8.00e-113	400.00
IUUC-Rno-105028	Rattus norvegicus	98.58	0.00e+00	1008.00
IUUC-Sce-106240	Saccharomyces cerevisiae	38.92	5.00e-95	341.00
IUUC-Sha-107107	Sarcophilus harrisii	84.00	0.00e+00	845.00
IUUC-Sja-107900	Schizosaccharomyces japonicus	48.97	3.00e-115	408.00
IUUC-Spo-108056	Schizosaccharomyces pombe	48.50	7.00e-114	403.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	51.81	6.00e-130	457.00
IUUC-Smo-108878	Selaginella moellendorffii	58.64	5.00e-145	507.00
IUUC-Sit-110550	Setaria italica	54.30	9.00e-129	453.00
IUUC-Sly-111446	Solanum lycopersicum	55.82	2.00e-134	472.00
IUUC-Stu-112491	Solanum tuberosum	55.60	1.00e-133	469.00
IUUC-Sar-112962	Sorex araneus	80.15	3.00e-119	421.00
IUUC-Sbi-114489	Sorghum bicolor	54.36	2.00e-123	435.00
IUUC-Sre-115222	Sporisorium reilianum	47.64	1.00e-131	463.00
IUUC-Ssc-116171	Sus scrofa	99.80	0.00e+00	1019.00
IUUC-Tgu-116878	Taeniopygia guttata	86.83	0.00e+00	867.00
IUUC-Tru-118222	Takifugu rubripes	89.78	0.00e+00	863.00
IUUC-Tni-119863	Tetraodon nigroviridis	90.52	0.00e+00	864.00
IUUC-Tca-121599	Theobroma cacao	57.14	8.00e-134	470.00
IUUC-Tre-122249	Trichoderma reesei	50.89	8.00e-134	470.00
IUUC-Tvi-122675	Trichoderma virens	50.98	7.00e-134	470.00
IUUC-Tae-123028	Triticum aestivum	54.69	6.00e-126	444.00
IUUC-Tur-126545	Triticum urartu	59.94	7.00e-104	370.00
IUUC-Tme-127151	Tuber melanosporum	54.03	3.00e-146	511.00
IUUC-Tbe-128056	Tupaia belangeri	89.69	1.00e-168	585.00
IUUC-Ttr-129055	Tursiops truncatus	98.39	0.00e+00	998.00
IUUC-Uma-129555	Ustilago maydis	47.45	4.00e-131	461.00
IUUC-Vda-130027	Verticillium dahliae	50.20	3.00e-134	471.00
IUUC-Vvi-131749	Vitis vinifera	55.11	3.00e-134	471.00
IUUC-Xtr-132808	Xenopus tropicalis	91.89	0.00e+00	942.00
IUUC-Xma-133183	Xiphophorus maculatus	90.93	0.00e+00	872.00
IUUC-Yli-134584	Yarrowia lipolytica	64.55	7.00e-131	461.00
IUUC-Zma-135640	Zea mays	68.04	5.00e-125	441.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence