iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090078

Ensembl Protein ID

ENSOARP00000014818.1

UniProt Accession

W5PWI5; W5PWI5_SHEEP

Genbank Protein ID

ENSOARP00000014818

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01042590

Gene Name

MDM2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013821.1	ENSOART00000015038.1	ENSOARP00000014818.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	78.63	0.00e+00	665.00	IUUC-Mmu-063207
E3 activity/RING/RING	82.65	0.00e+00	701.00	IUUC-Rno-105641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MCSTNMSVST DGAVSTSQIP ASEQETLVRP KPLLLKLLKS VGAQKDTYTM KEVIFYLGQY 60
IMTKRLYDEK QQHIVYCSND LLGDLFGVPS FSVKEHRKIY TMIYRNLIVV SQQEPSDSGT 120

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Nucleotide Sequence
(Fasta)

ATGTGCAGTA CCAACATGTC TGTGTCTACT GATGGTGCTG TAAGCACCTC ACAGATTCCA 60
GCTTCGGAAC AAGAGACCCT GGTTAGACCA AAGCCATTGC TTTTGAAGTT GTTGAAGTCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination

KEGG

oas:101103187

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004305	Anolis carolinensis	58.77	2.00e-122	432.00
IUUC-Ame-010675	Astyanax mexicanus	44.73	1.00e-85	310.00
IUUC-Bta-013270	Bos taurus	98.37	0.00e+00	853.00
IUUC-Cfa-020807	Canis familiaris	91.60	0.00e+00	772.00
IUUC-Cpo-022182	Cavia porcellus	88.16	0.00e+00	744.00
IUUC-Cre-022828	Chlamydomonas reinhardtii	35.42	8.00e-06	41.60
IUUC-Csa-023541	Chlorocebus sabaeus	93.08	0.00e+00	805.00
IUUC-Cho-024831	Choloepus hoffmanni	75.00	3.00e-87	314.00
IUUC-Cin-025448	Ciona intestinalis	28.77	7.00e-22	97.10
IUUC-Csv-026151	Ciona savignyi	31.17	1.00e-11	63.20
IUUC-Dre-028419	Danio rerio	43.70	1.00e-51	197.00
IUUC-Dno-028950	Dasypus novemcinctus	90.84	0.00e+00	799.00
IUUC-Dor-031048	Dipodomys ordii	71.14	3.00e-170	591.00
IUUC-Ete-032264	Echinops telfairi	67.95	3.00e-171	594.00
IUUC-Fca-035454	Felis catus	93.48	0.00e+00	826.00
IUUC-Fal-036720	Ficedula albicollis	61.46	3.00e-73	268.00
IUUC-Gmo-039296	Gadus morhua	40.67	8.00e-45	174.00
IUUC-Ggo-044948	Gorilla gorilla	85.74	0.00e+00	734.00
IUUC-Lch-050037	Latimeria chalumnae	56.59	1.00e-117	416.00
IUUC-Loc-051837	Lepisosteus oculatus	50.41	9.00e-114	403.00
IUUC-Laf-053483	Loxodonta africana	83.94	0.00e+00	728.00
IUUC-Mcc-055294	Macaca mulatta	93.28	0.00e+00	810.00
IUUC-Mga-060007	Meleagris gallopavo	64.46	4.00e-147	514.00
IUUC-Mmr-060673	Microcebus murinus	92.67	0.00e+00	830.00
IUUC-Mmu-063207	Mus musculus	78.63	0.00e+00	630.00
IUUC-Mpu-065836	Mustela putorius furo	92.26	0.00e+00	832.00
IUUC-Opr-070590	Ochotona princeps	84.29	0.00e+00	709.00
IUUC-Oan-072744	Ornithorhynchus anatinus	71.95	3.00e-167	581.00
IUUC-Oga-088135	Otolemur garnettii	82.83	0.00e+00	742.00
IUUC-Pan-092720	Papio anubis	93.28	0.00e+00	810.00
IUUC-Psi-093591	Pelodiscus sinensis	64.99	4.00e-131	461.00
IUUC-Pva-102488	Pteropus vampyrus	86.97	0.00e+00	717.00
IUUC-Rno-105641	Rattus norvegicus	82.65	0.00e+00	680.00
IUUC-Sar-112938	Sorex araneus	85.71	0.00e+00	766.00
IUUC-Ssc-115495	Sus scrofa	94.30	0.00e+00	806.00
IUUC-Tgu-116623	Taeniopygia guttata	64.44	1.00e-153	535.00
IUUC-Tru-117820	Takifugu rubripes	37.77	1.00e-68	253.00
IUUC-Tsy-119162	Tarsius syrichta	66.03	1.00e-89	322.00
IUUC-Tbe-127816	Tupaia belangeri	89.43	2.00e-121	428.00
IUUC-Ttr-129194	Tursiops truncatus	83.84	0.00e+00	676.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence