iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106626

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01071490

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000016744.1	ENSSHAT00000019880.1	ENSSHAP00000019723.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.50e-12	45.6	531	596

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk +     v++elpn+  w+ +kC+++
   Q: 531  AVCLVCGEAGKEDtveeeEakfnlMLMECSICNEIIHPGCLKVKesdgvVNDELPNC--WEGTKCNHA 596
           79*********9977765156789*********************************..******985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

GSRRLVDVMD VNSQKGTEMS MSQFVRYYEM PENQREKLYN VISLEFSHTK LENLVKRPNV 60
IDLVDWVDNM WPQHLKEKQT ESTNLIAEMK YPKVKKYCLM SVKGCFTDFH IDFGGTSVWY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGCCGGC GACTGGTGGA TGTGATGGAC GTCAACAGCC AGAAGGGCAC GGAGATGAGT 60
ATGTCCCAGT TCGTGCGCTA CTATGAGATG CCTGAAAACC AACGGGAGAA ATTGTACAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC

Pfam

PF00646--F-box
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	81.68	0.00e+00	1783.00
IUUC-Apl-003787	Anas platyrhynchos	78.93	0.00e+00	1735.00
IUUC-Aca-004247	Anolis carolinensis	71.93	0.00e+00	1528.00
IUUC-Ame-011114	Astyanax mexicanus	64.52	9.00e-126	444.00
IUUC-Bta-013531	Bos taurus	81.88	0.00e+00	1800.00
IUUC-Cja-018876	Callithrix jacchus	77.81	0.00e+00	1717.00
IUUC-Cfa-020857	Canis familiaris	81.73	0.00e+00	1793.00
IUUC-Cpo-021967	Cavia porcellus	79.46	0.00e+00	1667.00
IUUC-Csa-023210	Chlorocebus sabaeus	80.02	0.00e+00	1759.00
IUUC-Dre-028272	Danio rerio	59.97	0.00e+00	806.00
IUUC-Dno-030034	Dasypus novemcinctus	80.12	0.00e+00	1760.00
IUUC-Dor-030736	Dipodomys ordii	69.30	0.00e+00	825.00
IUUC-Eca-034255	Equus caballus	82.25	0.00e+00	1800.00
IUUC-Eeu-035038	Erinaceus europaeus	83.65	0.00e+00	1047.00
IUUC-Fca-035786	Felis catus	81.63	0.00e+00	1804.00
IUUC-Fal-037589	Ficedula albicollis	79.16	0.00e+00	1744.00
IUUC-Gga-041103	Gallus gallus	77.57	0.00e+00	866.00
IUUC-Gac-041304	Gasterosteus aculeatus	55.85	0.00e+00	1264.00
IUUC-Ggo-044522	Gorilla gorilla	79.44	0.00e+00	1440.00
IUUC-Hsa-045877	Homo sapiens	81.32	0.00e+00	1794.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	81.26	0.00e+00	1139.00
IUUC-Lch-049950	Latimeria chalumnae	73.00	0.00e+00	1629.00
IUUC-Loc-051972	Lepisosteus oculatus	66.24	0.00e+00	842.00
IUUC-Laf-053623	Loxodonta africana	80.50	0.00e+00	1738.00
IUUC-Mcc-054943	Macaca mulatta	80.50	0.00e+00	1781.00
IUUC-Meu-056259	Macropus eugenii	85.43	0.00e+00	1899.00
IUUC-Mga-059671	Meleagris gallopavo	80.17	0.00e+00	1771.00
IUUC-Mmr-061003	Microcebus murinus	81.85	0.00e+00	1793.00
IUUC-Mdo-062017	Monodelphis domestica	76.22	0.00e+00	680.00
IUUC-Mmu-063584	Mus musculus	80.31	0.00e+00	1754.00
IUUC-Mpu-066056	Mustela putorius furo	81.65	0.00e+00	1778.00
IUUC-Mlu-067850	Myotis lucifugus	81.19	0.00e+00	1801.00
IUUC-Nle-069837	Nomascus leucogenys	79.83	0.00e+00	1654.00
IUUC-Opr-070943	Ochotona princeps	79.59	0.00e+00	1705.00
IUUC-Ont-071663	Oreochromis niloticus	59.00	0.00e+00	1335.00
IUUC-Oan-072934	Ornithorhynchus anatinus	74.19	0.00e+00	1219.00
IUUC-Ocu-074706	Oryctolagus cuniculus	82.01	0.00e+00	1803.00
IUUC-Ola-086543	Oryzias latipes	58.35	0.00e+00	1301.00
IUUC-Oga-088671	Otolemur garnettii	71.15	0.00e+00	833.00
IUUC-Oar-089560	Ovis aries	80.21	0.00e+00	1760.00
IUUC-Ptr-090875	Pan troglodytes	81.32	0.00e+00	1810.00
IUUC-Pan-091788	Papio anubis	78.53	0.00e+00	1737.00
IUUC-Psi-093382	Pelodiscus sinensis	80.21	0.00e+00	1780.00
IUUC-Pma-094687	Petromyzon marinus	55.71	1.00e-90	327.00
IUUC-Pfo-096272	Poecilia formosa	57.15	0.00e+00	1253.00
IUUC-Pab-097907	Pongo abelii	76.69	0.00e+00	1642.00
IUUC-Pca-100628	Procavia capensis	81.95	0.00e+00	966.00
IUUC-Pva-102956	Pteropus vampyrus	75.04	0.00e+00	884.00
IUUC-Rno-105722	Rattus norvegicus	79.98	0.00e+00	1529.00
IUUC-Ssc-115918	Sus scrofa	79.77	0.00e+00	1463.00
IUUC-Tru-118638	Takifugu rubripes	62.48	0.00e+00	766.00
IUUC-Tsy-118820	Tarsius syrichta	81.33	0.00e+00	684.00
IUUC-Tbe-127654	Tupaia belangeri	73.15	0.00e+00	1066.00
IUUC-Ttr-128821	Tursiops truncatus	73.74	0.00e+00	1579.00
IUUC-Xtr-131823	Xenopus tropicalis	70.63	0.00e+00	1521.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence