iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053712

UUCD1 version

UUC-LoA-00837

Ensembl Protein ID

ENSLAFP00000024122.1

UniProt Accession

G3U8G4; G3U8G4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000008311.3	ENSLAFT00000035891.1	ENSLAFP00000024122.1
ENSLAFG00000008311.3	ENSLAFT00000008311.3	ENSLAFP00000006967.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.40e-21	74.8	370	401
UBD/Beta-Prp	3.80e-40	138.3	283	491

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 370  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 401
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 283  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPNQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 371
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 372  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSNRQGH 458
           ******99999.********************988874555555.55555555559*****************777778888888888* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 459  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 491
           ************9777899***********986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPTESGSCSA ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQGIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACAG AAAGCGGAAG TTGTTCAGCT GCTCGCCAGG CAAAACAGAA ACGCAAATCA 60
CATAGCCTTT CTATAAGAAG AACTAACAGC TCAGAACAGG AAAGGACGGG ACTACCAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	94.99	0.00e+00	942.00
IUUC-Apl-003647	Anas platyrhynchos	92.79	0.00e+00	925.00
IUUC-Aca-004759	Anolis carolinensis	92.18	0.00e+00	935.00
IUUC-Ame-011103	Astyanax mexicanus	55.53	1.00e-142	499.00
IUUC-Bta-012718	Bos taurus	93.99	0.00e+00	934.00
IUUC-Cel-018499	Caenorhabditis elegans	42.05	7.00e-95	340.00
IUUC-Cja-019492	Callithrix jacchus	94.59	0.00e+00	970.00
IUUC-Cfa-020199	Canis familiaris	94.99	0.00e+00	974.00
IUUC-Cpo-022500	Cavia porcellus	89.58	0.00e+00	924.00
IUUC-Csa-023567	Chlorocebus sabaeus	95.39	0.00e+00	977.00
IUUC-Cho-025071	Choloepus hoffmanni	69.14	0.00e+00	641.00
IUUC-Cin-025460	Ciona intestinalis	44.26	6.00e-100	357.00
IUUC-Csv-026042	Ciona savignyi	45.23	4.00e-103	367.00
IUUC-Dre-028214	Danio rerio	81.56	0.00e+00	848.00
IUUC-Dno-029826	Dasypus novemcinctus	95.69	0.00e+00	820.00
IUUC-Dor-030967	Dipodomys ordii	94.52	0.00e+00	871.00
IUUC-Dme-031936	Drosophila melanogaster	48.74	1.00e-113	402.00
IUUC-Ete-032452	Echinops telfairi	93.79	0.00e+00	959.00
IUUC-Eca-033278	Equus caballus	94.59	0.00e+00	973.00
IUUC-Eeu-034592	Erinaceus europaeus	81.76	0.00e+00	807.00
IUUC-Fca-036431	Felis catus	95.20	0.00e+00	976.00
IUUC-Fal-037149	Ficedula albicollis	91.58	0.00e+00	917.00
IUUC-Gmo-038476	Gadus morhua	78.37	0.00e+00	756.00
IUUC-Gga-041099	Gallus gallus	92.59	0.00e+00	926.00
IUUC-Gac-042374	Gasterosteus aculeatus	83.50	0.00e+00	809.00
IUUC-Ggo-044683	Gorilla gorilla	87.17	0.00e+00	882.00
IUUC-Hsa-046658	Homo sapiens	94.59	0.00e+00	970.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	95.85	0.00e+00	907.00
IUUC-Lch-050571	Latimeria chalumnae	83.96	0.00e+00	867.00
IUUC-Loc-052652	Lepisosteus oculatus	81.59	0.00e+00	851.00
IUUC-Mcc-055521	Macaca mulatta	95.39	0.00e+00	977.00
IUUC-Meu-056324	Macropus eugenii	89.98	0.00e+00	892.00
IUUC-Mga-060114	Meleagris gallopavo	92.79	0.00e+00	932.00
IUUC-Mmr-061176	Microcebus murinus	94.99	0.00e+00	969.00
IUUC-Mdo-061888	Monodelphis domestica	93.99	0.00e+00	920.00
IUUC-Mmu-063977	Mus musculus	94.99	0.00e+00	981.00
IUUC-Mpu-066220	Mustela putorius furo	81.17	1.00e-175	608.00
IUUC-Mlu-068155	Myotis lucifugus	94.99	0.00e+00	975.00
IUUC-Nle-069964	Nomascus leucogenys	94.79	0.00e+00	972.00
IUUC-Opr-070925	Ochotona princeps	93.19	1.00e-145	509.00
IUUC-Ont-071317	Oreochromis niloticus	85.37	0.00e+00	834.00
IUUC-Oan-072952	Ornithorhynchus anatinus	94.39	0.00e+00	948.00
IUUC-Ocu-073913	Oryctolagus cuniculus	95.99	0.00e+00	986.00
IUUC-Ola-087024	Oryzias latipes	84.00	0.00e+00	874.00
IUUC-Oga-087945	Otolemur garnettii	94.59	0.00e+00	978.00
IUUC-Oar-089854	Ovis aries	94.19	0.00e+00	929.00
IUUC-Ptr-091486	Pan troglodytes	94.79	0.00e+00	971.00
IUUC-Pan-091738	Papio anubis	95.39	0.00e+00	977.00
IUUC-Psi-093953	Pelodiscus sinensis	92.38	0.00e+00	929.00
IUUC-Pma-094560	Petromyzon marinus	73.43	0.00e+00	757.00
IUUC-Pfo-097222	Poecilia formosa	81.96	0.00e+00	820.00
IUUC-Pab-098778	Pongo abelii	90.18	0.00e+00	911.00
IUUC-Pca-100852	Procavia capensis	93.99	0.00e+00	947.00
IUUC-Pva-103130	Pteropus vampyrus	93.06	4.00e-130	457.00
IUUC-Rno-105848	Rattus norvegicus	86.77	0.00e+00	881.00
IUUC-Sha-106750	Sarcophilus harrisii	94.39	0.00e+00	951.00
IUUC-Sar-113749	Sorex araneus	85.97	0.00e+00	858.00
IUUC-Ssc-115691	Sus scrofa	92.18	0.00e+00	913.00
IUUC-Tgu-117365	Taeniopygia guttata	90.98	0.00e+00	872.00
IUUC-Tru-117595	Takifugu rubripes	83.17	0.00e+00	819.00
IUUC-Tsy-118973	Tarsius syrichta	73.84	6.00e-147	513.00
IUUC-Tni-120545	Tetraodon nigroviridis	82.44	0.00e+00	853.00
IUUC-Tbe-127976	Tupaia belangeri	70.94	0.00e+00	676.00
IUUC-Ttr-128472	Tursiops truncatus	91.38	0.00e+00	924.00
IUUC-Xtr-132621	Xenopus tropicalis	90.58	0.00e+00	893.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence