iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033491

Ensembl Protein ID

ENSECAP00000017407.1

UniProt Accession

F7DII4; F7DII4_HORSE

Protein Name

Uncharacterized protein

Gene Name

AHI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019646.1	ENSECAT00000021153.1	ENSECAP00000017407.1
ENSECAG00000019646.1	ENSECAT00000021170.1	ENSECAP00000017422.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-18	66.1	643	673
UBD/SH3	1.30e-14	54.1	1045	1097

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWD 29
           gH + +++l++  +d++++++s Dgt ++W 
   Q: 643  GHLNIIYDLCWskDDRYVLTASSDGTARIWK 673
           79999*******666***************7 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g++G fP+n v+
   Q: 1045 TVVALYDYTANRSDELTIHRGDIIRVF--FKDNEDWWYG-SVGKGQEGYFPANHVA 1097
           689***********************9..8999******.7************996 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MPTVESEAKV KTKVRFEELL KTHNDLIRER KKLKKKIGKS GEKLSVTNIR AHLPLLYVCS 60
SDDPECISIS PQKITETKSD GLSATDTFDP EKSMRVTKNK LRNPQSTPEN PEDVSVEEDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCACTG GTAAGACTTC TATGAAATTT ATGTATGCAA TACATATTAT TTATTTATTT 60
TAAAGTTTGG GTTATTTTAA GGGGTTCTTT AACTGATAAT GAATAAAGTA GATGTCATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR023302--Pept_S9A_N
IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	86.87	0.00e+00	1692.00
IUUC-Apl-004057	Anas platyrhynchos	50.43	0.00e+00	1057.00
IUUC-Aca-004306	Anolis carolinensis	54.73	0.00e+00	946.00
IUUC-Ame-010981	Astyanax mexicanus	48.98	0.00e+00	850.00
IUUC-Bta-013129	Bos taurus	86.64	0.00e+00	1893.00
IUUC-Cja-018979	Callithrix jacchus	78.17	0.00e+00	1565.00
IUUC-Cfa-020121	Canis familiaris	85.23	0.00e+00	1922.00
IUUC-Cpo-022219	Cavia porcellus	78.72	0.00e+00	1310.00
IUUC-Csa-023991	Chlorocebus sabaeus	80.83	0.00e+00	1883.00
IUUC-Cho-024782	Choloepus hoffmanni	77.57	0.00e+00	939.00
IUUC-Cin-025149	Ciona intestinalis	40.03	2.00e-168	585.00
IUUC-Csv-026188	Ciona savignyi	38.90	3.00e-124	438.00
IUUC-Dre-028737	Danio rerio	49.65	0.00e+00	857.00
IUUC-Dno-029756	Dasypus novemcinctus	80.21	0.00e+00	1728.00
IUUC-Dor-030821	Dipodomys ordii	69.48	0.00e+00	1481.00
IUUC-Ete-032237	Echinops telfairi	76.86	0.00e+00	1637.00
IUUC-Eeu-034812	Erinaceus europaeus	74.47	0.00e+00	966.00
IUUC-Fca-035868	Felis catus	85.06	0.00e+00	1848.00
IUUC-Fal-037571	Ficedula albicollis	54.71	0.00e+00	794.00
IUUC-Gmo-039358	Gadus morhua	50.52	0.00e+00	790.00
IUUC-Gga-040233	Gallus gallus	52.39	0.00e+00	988.00
IUUC-Gac-041744	Gasterosteus aculeatus	49.14	0.00e+00	790.00
IUUC-Ggo-044766	Gorilla gorilla	81.98	0.00e+00	1916.00
IUUC-Hsa-046660	Homo sapiens	81.82	0.00e+00	1910.00
IUUC-Itr-048282	Ictidomys tridecemlineatus	82.37	0.00e+00	1880.00
IUUC-Loc-052658	Lepisosteus oculatus	51.78	0.00e+00	927.00
IUUC-Laf-053564	Loxodonta africana	88.06	0.00e+00	1476.00
IUUC-Mcc-055480	Macaca mulatta	81.00	0.00e+00	1901.00
IUUC-Meu-056362	Macropus eugenii	58.58	0.00e+00	812.00
IUUC-Mga-060033	Meleagris gallopavo	50.69	0.00e+00	1068.00
IUUC-Mmr-061075	Microcebus murinus	81.87	0.00e+00	1886.00
IUUC-Mdo-062818	Monodelphis domestica	53.55	0.00e+00	1162.00
IUUC-Mmu-063987	Mus musculus	77.61	0.00e+00	1588.00
IUUC-Mpu-066242	Mustela putorius furo	82.97	0.00e+00	1837.00
IUUC-Mlu-067123	Myotis lucifugus	80.02	0.00e+00	1721.00
IUUC-Nle-069793	Nomascus leucogenys	81.65	0.00e+00	1924.00
IUUC-Opr-071110	Ochotona princeps	73.15	0.00e+00	847.00
IUUC-Ont-072179	Oreochromis niloticus	49.71	0.00e+00	821.00
IUUC-Oan-073201	Ornithorhynchus anatinus	64.04	7.00e-137	479.00
IUUC-Ocu-074224	Oryctolagus cuniculus	82.04	0.00e+00	1932.00
IUUC-Ola-086818	Oryzias latipes	52.31	2.00e-71	261.00
IUUC-Oga-088338	Otolemur garnettii	84.13	0.00e+00	1740.00
IUUC-Oar-089247	Ovis aries	83.63	0.00e+00	1932.00
IUUC-Ptr-090830	Pan troglodytes	82.65	0.00e+00	1873.00
IUUC-Pan-092469	Papio anubis	81.82	0.00e+00	1924.00
IUUC-Psi-093183	Pelodiscus sinensis	50.79	0.00e+00	1073.00
IUUC-Pma-094415	Petromyzon marinus	47.58	2.00e-157	549.00
IUUC-Pfo-096577	Poecilia formosa	54.05	0.00e+00	766.00
IUUC-Pab-098236	Pongo abelii	80.52	0.00e+00	1620.00
IUUC-Pca-100560	Procavia capensis	67.95	0.00e+00	1476.00
IUUC-Pva-102565	Pteropus vampyrus	78.92	0.00e+00	1433.00
IUUC-Rno-104881	Rattus norvegicus	78.22	0.00e+00	1615.00
IUUC-Sha-106577	Sarcophilus harrisii	64.72	2.00e-162	565.00
IUUC-Sar-113265	Sorex araneus	72.60	0.00e+00	1541.00
IUUC-Ssc-116174	Sus scrofa	86.32	0.00e+00	1929.00
IUUC-Tgu-116618	Taeniopygia guttata	49.47	0.00e+00	891.00
IUUC-Tru-117761	Takifugu rubripes	43.16	0.00e+00	680.00
IUUC-Tsy-119557	Tarsius syrichta	77.99	0.00e+00	917.00
IUUC-Tni-119782	Tetraodon nigroviridis	50.06	0.00e+00	800.00
IUUC-Tbe-127529	Tupaia belangeri	70.38	3.00e-145	509.00
IUUC-Ttr-128444	Tursiops truncatus	82.18	0.00e+00	1844.00
IUUC-Vpa-130337	Vicugna pacos	77.28	0.00e+00	1676.00
IUUC-Xtr-132055	Xenopus tropicalis	57.31	0.00e+00	740.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence