iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010088.1	ENSPSIT00000011263.1	ENSPSIP00000011207.1
ENSPSIG00000010088.1	ENSPSIT00000011277.1	ENSPSIP00000011221.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.50e-72	243.1	3	555

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..aeekkkkknkslisdlFqgqlksqikclecdn 161
           ++++k + +++g++q+DaqEfl +lld+++e+l++   k+  ++  +     +d    e      +++++++lFq q++s+++c++c++
   Q: 3    NIVSKNSMQYRGNSQHDAQEFLLWLLDRVHEDLNN-VVKSSGRSPLKP--PVEDAalLEAPGFPVSSTFVQELFQAQYRSSLTCPHCQK 88
           788999999************************55.222222222222..22222224555566777********************** PP
   S: 162  vssreepfldlslpvpgkeetkke................................................................. 185
           +s++++pfl +slp+p  +++ ++                                                                 
   Q: 89   QSNTFDPFLCISLPIPLPHTR-PLyitvvyqgkcshcmrigvavplsgtvaklreavsmetkipteqivltemyydgfhrsfcdtddld 176
           ****************88755.34689************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 177  tvhesdcifafetpeifrpegilsqrgihlnnnlnnlkydpehhktslaqgvgksgkqetstrsaardkivllvcnrastgqqgkrfgq 265
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 266  pfvlhlektikwdllqkeilekmqyilrpsacmqvcpfslrvvsavgityllpqeerplchptveralkscghggtahvklvvewdmgg 354
           ***************************************************************************************** PP
   S: 186  ................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfsee 242
                                           sl++c++ +tkee+l  ++++ c++ck++q+ + +l+l++lP+vLi+hLkRf  ++e
   Q: 355  svalfvtvedeyvpdsesvrqqrelhhqpqscSLSQCFQLYTKEEQLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRF--RQE 441
           ************************************************************************************..99* PP
   S: 243  qksrekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssGHYvayvknekgk.Wllfd 310
           +++r k+++ v+fpl+ Ld++p+++++++++ +                   +++Y+L+av++H+G+++ GHY+ay+kn+ ++ W++fd
   Q: 442  GDRRMKLQNMVKFPLTgLDMTPHVVKRSQSSWSlpshwspwrrpyglgrdpeDYIYDLYAVCNHHGTMQAGHYTAYCKNSVDGlWYCFD 530
           *************************977666559999999999999999999***************************87777***** PP
   S: 311  DskVtevkeeevleetgstaYvlfYkrr 338
           D+ V+++ e+ev++   +taY+lfY+rr
   Q: 531  DTDVQQLAENEVCK---QTAYILFYQRR 555
           **************...*********96 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LQNIVSKNSM QYRGNSQHDA QEFLLWLLDR VHEDLNNVVK SSGRSPLKPP VEDAALLEAP 60
GFPVSSTFVQ ELFQAQYRSS LTCPHCQKQS NTFDPFLCIS LPIPLPHTRP LYITVVYQGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGACTGTTC CTCTGCAGAA CATTGTCTCG AAGAACTCCA TGCAGTACCG AGGGAACTCG 60
CAGCATGATG CCCAGGAGTT CTTGCTCTGG CTGTTGGACA GAGTTCACGA AGACCTCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001207	Ailuropoda melanoleuca	83.31	0.00e+00	1248.00
IUUC-Apl-003186	Anas platyrhynchos	82.64	0.00e+00	1533.00
IUUC-Aca-004949	Anolis carolinensis	71.06	0.00e+00	1298.00
IUUC-Ame-010968	Astyanax mexicanus	67.65	0.00e+00	945.00
IUUC-Bta-013271	Bos taurus	82.63	0.00e+00	1208.00
IUUC-Cja-019663	Callithrix jacchus	83.21	0.00e+00	1241.00
IUUC-Cfa-021258	Canis familiaris	83.59	0.00e+00	1282.00
IUUC-Csa-024188	Chlorocebus sabaeus	84.58	0.00e+00	1244.00
IUUC-Cho-024813	Choloepus hoffmanni	78.57	0.00e+00	1072.00
IUUC-Csv-026086	Ciona savignyi	38.12	3.00e-120	425.00
IUUC-Dre-027372	Danio rerio	69.42	0.00e+00	979.00
IUUC-Dno-029964	Dasypus novemcinctus	82.83	0.00e+00	1275.00
IUUC-Dor-030448	Dipodomys ordii	66.07	0.00e+00	856.00
IUUC-Dme-032088	Drosophila melanogaster	37.10	9.00e-52	199.00
IUUC-Ete-032975	Echinops telfairi	63.29	0.00e+00	1117.00
IUUC-Eca-034030	Equus caballus	73.84	0.00e+00	1419.00
IUUC-Eeu-034629	Erinaceus europaeus	66.75	0.00e+00	912.00
IUUC-Fca-035788	Felis catus	83.21	0.00e+00	1272.00
IUUC-Fal-036874	Ficedula albicollis	80.04	0.00e+00	1449.00
IUUC-Gmo-039479	Gadus morhua	67.54	0.00e+00	977.00
IUUC-Gga-041092	Gallus gallus	81.95	0.00e+00	1496.00
IUUC-Gac-041778	Gasterosteus aculeatus	57.67	0.00e+00	1010.00
IUUC-Ggo-044782	Gorilla gorilla	82.06	5.00e-127	448.00
IUUC-Hsa-046805	Homo sapiens	83.81	0.00e+00	1280.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	75.53	0.00e+00	1412.00
IUUC-Lch-050332	Latimeria chalumnae	66.82	0.00e+00	1162.00
IUUC-Loc-051953	Lepisosteus oculatus	61.52	0.00e+00	1104.00
IUUC-Laf-054033	Loxodonta africana	48.05	3.00e-159	555.00
IUUC-Mcc-055398	Macaca mulatta	84.70	0.00e+00	1274.00
IUUC-Meu-056822	Macropus eugenii	70.70	0.00e+00	1269.00
IUUC-Mga-060115	Meleagris gallopavo	79.20	0.00e+00	1489.00
IUUC-Mmr-061150	Microcebus murinus	83.33	0.00e+00	1268.00
IUUC-Mdo-062700	Monodelphis domestica	77.17	0.00e+00	1497.00
IUUC-Mmu-063512	Mus musculus	83.65	0.00e+00	1187.00
IUUC-Mpu-066059	Mustela putorius furo	80.94	0.00e+00	1194.00
IUUC-Mlu-067870	Myotis lucifugus	72.93	0.00e+00	1327.00
IUUC-Nle-069898	Nomascus leucogenys	83.69	0.00e+00	1277.00
IUUC-Opr-070338	Ochotona princeps	68.03	2.00e-173	603.00
IUUC-Ont-072354	Oreochromis niloticus	67.16	0.00e+00	951.00
IUUC-Oan-073175	Ornithorhynchus anatinus	83.67	0.00e+00	1283.00
IUUC-Ocu-074014	Oryctolagus cuniculus	47.58	2.00e-160	558.00
IUUC-Ola-086745	Oryzias latipes	66.42	0.00e+00	913.00
IUUC-Oga-089021	Otolemur garnettii	82.97	0.00e+00	1217.00
IUUC-Oar-090016	Ovis aries	83.11	0.00e+00	1217.00
IUUC-Ptr-090864	Pan troglodytes	83.57	0.00e+00	1274.00
IUUC-Pan-092370	Papio anubis	84.83	0.00e+00	1249.00
IUUC-Pfo-097427	Poecilia formosa	71.59	0.00e+00	954.00
IUUC-Pab-098104	Pongo abelii	80.94	0.00e+00	1216.00
IUUC-Pca-100640	Procavia capensis	78.86	9.00e-92	332.00
IUUC-Pva-102287	Pteropus vampyrus	79.54	0.00e+00	1145.00
IUUC-Rno-106033	Rattus norvegicus	80.90	0.00e+00	1251.00
IUUC-Sha-107041	Sarcophilus harrisii	77.78	0.00e+00	1501.00
IUUC-Sar-113105	Sorex araneus	42.98	5.00e-127	448.00
IUUC-Ssc-116412	Sus scrofa	81.72	4.00e-135	474.00
IUUC-Tgu-116889	Taeniopygia guttata	79.53	0.00e+00	1518.00
IUUC-Tru-117929	Takifugu rubripes	65.44	0.00e+00	929.00
IUUC-Tsy-118887	Tarsius syrichta	75.54	0.00e+00	1062.00
IUUC-Tni-120236	Tetraodon nigroviridis	57.54	0.00e+00	963.00
IUUC-Tbe-127491	Tupaia belangeri	81.07	3.00e-108	386.00
IUUC-Ttr-128210	Tursiops truncatus	77.22	0.00e+00	1147.00
IUUC-Vpa-130222	Vicugna pacos	70.98	2.00e-176	612.00
IUUC-Xtr-132509	Xenopus tropicalis	64.93	0.00e+00	1222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence