iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072872

Ensembl Protein ID

ENSOANP00000014544.3

UniProt Accession

F7ETE0; F7ETE0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009137.4	ENSOANT00000014547.4	ENSOANP00000014544.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.40e-17	64.0	32	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lv+++ ef+ahk+ La++S++F+ +f+ +++e++ ++++++k++ +  f+++l+F+Y g++++
   Q: 32   DVTLVIEDHEFQAHKALLATQSDYFRIMFTADMRERD-QDKIHLKGLTAPGFSHVLQFMYYGTIEL 96
           9***********************************9.************************9876 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MAGDVEGFSS SLHDTSVSAG FRALYEEGLL LDVTLVIEDH EFQAHKALLA TQSDYFRIMF 60
TADMRERDQD KIHLKGLTAP GFSHVLQFMY YGTIELSMAT VHEILQAAMY VQLLEVVKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATTCATG GCAGGGGACG TGGAAGGATT CAGTTCCTCC CTCCACGACA CCAGCGTCTC 60
TGCGGGCTTC AGGGCGCTGT ACGAGGAGGG CCTGCTGCTG GACGTGACGC TGGTCATCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030597--KLHL15
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

KEGG

oaa:100093466

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001418	Ailuropoda melanoleuca	90.73	0.00e+00	1082.00
IUUC-Apl-003970	Anas platyrhynchos	93.54	0.00e+00	1112.00
IUUC-Aca-005217	Anolis carolinensis	93.54	0.00e+00	1113.00
IUUC-Ame-011065	Astyanax mexicanus	86.09	0.00e+00	1065.00
IUUC-Bta-012443	Bos taurus	90.07	0.00e+00	1077.00
IUUC-Cja-019831	Callithrix jacchus	90.23	0.00e+00	1076.00
IUUC-Cfa-020941	Canis familiaris	90.73	0.00e+00	1082.00
IUUC-Cpo-021730	Cavia porcellus	90.23	0.00e+00	1079.00
IUUC-Csa-023247	Chlorocebus sabaeus	90.40	0.00e+00	1077.00
IUUC-Dre-028474	Danio rerio	86.42	0.00e+00	1074.00
IUUC-Dno-029411	Dasypus novemcinctus	91.39	0.00e+00	1087.00
IUUC-Dor-030576	Dipodomys ordii	90.07	0.00e+00	1076.00
IUUC-Ete-032327	Echinops telfairi	88.41	0.00e+00	1045.00
IUUC-Eca-033477	Equus caballus	90.89	0.00e+00	1085.00
IUUC-Fca-035546	Felis catus	90.56	0.00e+00	1081.00
IUUC-Fal-037370	Ficedula albicollis	93.54	0.00e+00	1112.00
IUUC-Gmo-038961	Gadus morhua	82.76	0.00e+00	981.00
IUUC-Gga-041049	Gallus gallus	93.38	0.00e+00	1110.00
IUUC-Gac-042003	Gasterosteus aculeatus	83.09	0.00e+00	996.00
IUUC-Ggo-044451	Gorilla gorilla	90.40	0.00e+00	1077.00
IUUC-Hsa-045874	Homo sapiens	90.23	0.00e+00	1076.00
IUUC-Itr-048357	Ictidomys tridecemlineatus	90.40	0.00e+00	1079.00
IUUC-Lch-049603	Latimeria chalumnae	85.59	5.00e-122	429.00
IUUC-Loc-052300	Lepisosteus oculatus	88.91	0.00e+00	1098.00
IUUC-Laf-054459	Loxodonta africana	91.56	0.00e+00	1089.00
IUUC-Mcc-054846	Macaca mulatta	90.40	0.00e+00	1077.00
IUUC-Meu-056797	Macropus eugenii	91.48	4.00e-109	387.00
IUUC-Mga-059446	Meleagris gallopavo	93.54	0.00e+00	1112.00
IUUC-Mmr-061125	Microcebus murinus	89.74	0.00e+00	1072.00
IUUC-Mdo-062947	Monodelphis domestica	91.06	0.00e+00	1072.00
IUUC-Mmu-063708	Mus musculus	90.73	0.00e+00	1080.00
IUUC-Mpu-066447	Mustela putorius furo	90.50	0.00e+00	1071.00
IUUC-Mlu-066999	Myotis lucifugus	86.45	0.00e+00	909.00
IUUC-Nle-069918	Nomascus leucogenys	90.40	0.00e+00	1077.00
IUUC-Ont-071446	Oreochromis niloticus	83.31	0.00e+00	973.00
IUUC-Ocu-073969	Oryctolagus cuniculus	89.57	0.00e+00	838.00
IUUC-Ola-087557	Oryzias latipes	81.71	5.00e-149	519.00
IUUC-Oga-088567	Otolemur garnettii	90.71	0.00e+00	1076.00
IUUC-Oar-089882	Ovis aries	90.23	0.00e+00	1078.00
IUUC-Ptr-091229	Pan troglodytes	90.49	0.00e+00	1051.00
IUUC-Pan-091977	Papio anubis	90.40	0.00e+00	1077.00
IUUC-Psi-093496	Pelodiscus sinensis	91.16	6.00e-150	523.00
IUUC-Pfo-096759	Poecilia formosa	82.57	0.00e+00	991.00
IUUC-Pab-098480	Pongo abelii	90.40	0.00e+00	1077.00
IUUC-Rno-105500	Rattus norvegicus	90.73	0.00e+00	1080.00
IUUC-Sha-106521	Sarcophilus harrisii	90.85	0.00e+00	1043.00
IUUC-Ssc-116372	Sus scrofa	90.40	0.00e+00	1082.00
IUUC-Tgu-116481	Taeniopygia guttata	93.54	0.00e+00	1112.00
IUUC-Tru-118542	Takifugu rubripes	80.97	0.00e+00	981.00
IUUC-Tsy-118848	Tarsius syrichta	89.55	4.00e-118	417.00
IUUC-Tni-119989	Tetraodon nigroviridis	81.22	0.00e+00	920.00
IUUC-Tbe-127485	Tupaia belangeri	90.56	0.00e+00	1079.00
IUUC-Ttr-129214	Tursiops truncatus	90.07	0.00e+00	1075.00
IUUC-Vpa-130261	Vicugna pacos	87.42	0.00e+00	1038.00
IUUC-Xtr-132092	Xenopus tropicalis	89.53	0.00e+00	1030.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence