iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004098

Ensembl Protein ID

ENSAPLP00000006711.1

UniProt Accession

U3IHI9; U3IHI9_ANAPL

Genbank Protein ID

ENSAPLP00000006711

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01132162

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000007038.1	ENSAPLT00000007359.1	ENSAPLP00000006711.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-32	108.3	365	396
UBD/Beta-Prp	1.30e-49	168.7	363	641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gH+++v+cl+      +ll sGs D+tikvWD+
   Q: 365  GHQGPVWCLCVysiG-DLLFSGSSDKTIKVWDT 396
           8********965643.89**************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           + gh+   + c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++ +   l +gs D ti vwd+++ + v t+++
   Q: 363  FVGHQGP-VWCLCVYSIGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGN--KLYSGSADCTIIVWDIQNLQKVNTIRA 448
           5556655.5559999*******************846678899****************9..6************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           h++ v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v ++  n+l sGs+ +t+++Wd+++ ++++ l+    
   Q: 449  HDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVASQ--NYLYSGSY-QTIKIWDIRNLECVHVLQT-SG 530
           *******99999..9******.9*******7368888888**************99..*******9.79***************99.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +svys++++    ++v g + + + +wd++t+e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv
   Q: 531  GSVYSIAVTN--HHIVCGTYENLIHVWDIETKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSV 617
           *********9..8***********************************99888************************************ PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           ++ av   ++  l++g+ ds+v++w +
   Q: 618  TALAV---SRGRLFSGAVDSTVKVWTC 641
           ****9...*****************86 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

METTFGPAYS AVTTITKADG TNTFKQHRRT PSSSSTLTYS PRDEDDGMPP ISTPRRSDSA 60
ISVRSLHSES NMSLRSTFSL HEEEEEPEPL VFAEQPSVKL CCQLCCSVFK DPVITTCGHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGCAAAC TTCCCATGAC TAACAAGTGC TGGTTGGATT ATGAGCTCAA ACAAGAACGC 60
TCGCTACAAT CGTTTCTCCA GTGGCACAAC GAACATCACT ACTTCTGAAA ACACTAACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	94.57	0.00e+00	1195.00
IUUC-Aca-004852	Anolis carolinensis	93.86	0.00e+00	980.00
IUUC-Ame-011275	Astyanax mexicanus	87.66	0.00e+00	948.00
IUUC-Bta-013153	Bos taurus	94.85	0.00e+00	1193.00
IUUC-Cja-019243	Callithrix jacchus	93.92	0.00e+00	1150.00
IUUC-Cfa-020036	Canis familiaris	95.16	0.00e+00	1202.00
IUUC-Cpo-022194	Cavia porcellus	94.98	0.00e+00	1195.00
IUUC-Csa-023363	Chlorocebus sabaeus	95.16	0.00e+00	1200.00
IUUC-Cin-025279	Ciona intestinalis	58.91	0.00e+00	802.00
IUUC-Csv-026163	Ciona savignyi	64.55	0.00e+00	777.00
IUUC-Dre-027998	Danio rerio	92.98	0.00e+00	1141.00
IUUC-Dno-029356	Dasypus novemcinctus	93.30	2.00e-127	447.00
IUUC-Dor-030750	Dipodomys ordii	93.45	0.00e+00	1167.00
IUUC-Eca-033671	Equus caballus	79.45	0.00e+00	927.00
IUUC-Eeu-034765	Erinaceus europaeus	95.07	3.00e-162	565.00
IUUC-Fca-035843	Felis catus	95.16	0.00e+00	1204.00
IUUC-Fal-037237	Ficedula albicollis	99.53	0.00e+00	1255.00
IUUC-Gmo-038779	Gadus morhua	83.31	0.00e+00	1026.00
IUUC-Gga-040579	Gallus gallus	99.69	0.00e+00	1255.00
IUUC-Gac-042233	Gasterosteus aculeatus	87.77	0.00e+00	1141.00
IUUC-Gma-042914	Glycine max	27.54	2.00e-19	90.10
IUUC-Ggo-045147	Gorilla gorilla	94.70	0.00e+00	1194.00
IUUC-Hsa-046117	Homo sapiens	94.85	0.00e+00	1196.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	95.01	0.00e+00	1202.00
IUUC-Lch-050593	Latimeria chalumnae	95.94	0.00e+00	1190.00
IUUC-Loc-052444	Lepisosteus oculatus	95.16	0.00e+00	1236.00
IUUC-Laf-053499	Loxodonta africana	88.61	0.00e+00	1147.00
IUUC-Mcc-055038	Macaca mulatta	95.01	0.00e+00	1197.00
IUUC-Meu-056610	Macropus eugenii	95.55	0.00e+00	903.00
IUUC-Mtr-057641	Medicago truncatula	27.73	3.00e-20	92.80
IUUC-Mga-060183	Meleagris gallopavo	99.22	0.00e+00	1246.00
IUUC-Mmr-061133	Microcebus murinus	93.05	0.00e+00	1125.00
IUUC-Mdo-062312	Monodelphis domestica	96.26	0.00e+00	1212.00
IUUC-Mmu-063844	Mus musculus	95.36	0.00e+00	1175.00
IUUC-Mpu-066552	Mustela putorius furo	95.01	0.00e+00	1193.00
IUUC-Mlu-067719	Myotis lucifugus	95.01	0.00e+00	1171.00
IUUC-Nle-070045	Nomascus leucogenys	95.04	0.00e+00	1167.00
IUUC-Opr-070927	Ochotona princeps	92.82	0.00e+00	1171.00
IUUC-Ont-072680	Oreochromis niloticus	90.67	0.00e+00	1156.00
IUUC-Oan-073521	Ornithorhynchus anatinus	94.00	3.00e-52	195.00
IUUC-Ogu-077987	Oryza glumaepatula	25.43	4.00e-19	89.00
IUUC-Ola-087454	Oryzias latipes	90.98	0.00e+00	1207.00
IUUC-Oga-088380	Otolemur garnettii	95.01	0.00e+00	1199.00
IUUC-Oar-089558	Ovis aries	77.05	0.00e+00	931.00
IUUC-Ptr-091606	Pan troglodytes	94.70	0.00e+00	1194.00
IUUC-Pan-092227	Papio anubis	95.01	0.00e+00	1197.00
IUUC-Psi-093853	Pelodiscus sinensis	90.98	0.00e+00	1021.00
IUUC-Pma-094541	Petromyzon marinus	81.65	2.00e-157	547.00
IUUC-Pfo-096237	Poecilia formosa	91.40	0.00e+00	1156.00
IUUC-Pab-097589	Pongo abelii	94.85	0.00e+00	1196.00
IUUC-Pca-100375	Procavia capensis	93.72	0.00e+00	1155.00
IUUC-Pva-102434	Pteropus vampyrus	95.32	0.00e+00	1204.00
IUUC-Rno-105443	Rattus norvegicus	95.52	0.00e+00	1178.00
IUUC-Sha-106517	Sarcophilus harrisii	95.96	0.00e+00	1206.00
IUUC-Ssc-115990	Sus scrofa	94.54	0.00e+00	1193.00
IUUC-Tgu-117222	Taeniopygia guttata	99.06	0.00e+00	1241.00
IUUC-Tru-118392	Takifugu rubripes	90.84	0.00e+00	1165.00
IUUC-Tni-120220	Tetraodon nigroviridis	90.40	0.00e+00	1154.00
IUUC-Tbe-128045	Tupaia belangeri	96.53	6.00e-158	550.00
IUUC-Ttr-128203	Tursiops truncatus	91.26	0.00e+00	1135.00
IUUC-Xtr-132043	Xenopus tropicalis	95.48	0.00e+00	1239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence