iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132043

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01012732

Gene Name

traf7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000031263.1	ENSXETT00000060869.1	ENSXETP00000060803.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-31	106.4	390	421
UBD/Beta-Prp	3.60e-48	164.4	388	666

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gH+++v+cl+      +ll sGs D+tikvWD+
   Q: 390  GHQGPVWCLCVysiG-DLLFSGSSDKTIKVWDT 421
           8********965643.89**************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           + gh+  v+ c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++ +   l +gs D ti vwd++t   v t+++
   Q: 388  FVGHQGPVW-CLCVYSIGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGS--KLYSGSADCTIIVWDIQTLLKVNTIRA 473
           556666555.59999*******************846678899*****************..6************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           h++ v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v ++  n+l sGs+ +t+++Wd++t ++ + l+    
   Q: 474  HDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTDLKLKKELTGLNHWVRALVASQ--NYLYSGSY-QTIKIWDIRTLECAHVLQT-SG 555
           *******99999..9******.9*******7479999999***************9..*******9.79***************99.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +svys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv
   Q: 556  GSVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSV 642
           *********9..8***********************************99888************************************ PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           ++ av   ++  l++g+ ds+v++w +
   Q: 643  TALAV---SRGRLFSGAVDSTVKVWTC 666
           ****9...*****************86 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MTSNKNPRFN HFSAGASNLT LTENSNGTRM ETTFGPAFSA VTTITKADGT KHRRTPSTSS 60
TLAFSPRDED DVMPPISTPR RSDSAISVRS LHSESTMSLR STFSLHEEEE EPDPLVFAEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCACTCCC TACGTCCCGG CCAGCACGCA CACACACAGA CTTGGGGCTG TTGTGAAATC 60
ATCTCCTGTA CGACCGGCAG GGAAATGTCC TAGTGAAGGC ACCGCGCAGC TCCGGGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

KEGG

xtr:100216042

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	91.08	0.00e+00	1195.00
IUUC-Apl-004098	Anas platyrhynchos	95.48	0.00e+00	1205.00
IUUC-Aca-004852	Anolis carolinensis	89.54	0.00e+00	986.00
IUUC-Ame-011275	Astyanax mexicanus	84.08	0.00e+00	953.00
IUUC-Bta-013153	Bos taurus	92.09	0.00e+00	1201.00
IUUC-Cja-019243	Callithrix jacchus	90.37	0.00e+00	1157.00
IUUC-Cfa-020036	Canis familiaris	92.09	0.00e+00	1213.00
IUUC-Cpo-022194	Cavia porcellus	91.45	0.00e+00	1196.00
IUUC-Csa-023363	Chlorocebus sabaeus	91.79	0.00e+00	1206.00
IUUC-Cin-025279	Ciona intestinalis	59.53	0.00e+00	809.00
IUUC-Csv-026163	Ciona savignyi	64.43	0.00e+00	774.00
IUUC-Dre-027998	Danio rerio	91.55	0.00e+00	1133.00
IUUC-Dno-029356	Dasypus novemcinctus	90.62	1.00e-124	438.00
IUUC-Dor-030750	Dipodomys ordii	89.85	0.00e+00	1162.00
IUUC-Eca-033671	Equus caballus	77.04	0.00e+00	923.00
IUUC-Eeu-034765	Erinaceus europaeus	94.74	2.00e-161	562.00
IUUC-Fca-035843	Felis catus	91.79	0.00e+00	1211.00
IUUC-Fal-037237	Ficedula albicollis	93.88	0.00e+00	1246.00
IUUC-Gmo-038779	Gadus morhua	80.65	0.00e+00	1034.00
IUUC-Gga-040579	Gallus gallus	93.73	0.00e+00	1243.00
IUUC-Gac-042233	Gasterosteus aculeatus	85.37	0.00e+00	1129.00
IUUC-Ggo-045147	Gorilla gorilla	91.64	0.00e+00	1204.00
IUUC-Hsa-046117	Homo sapiens	91.64	0.00e+00	1204.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	92.09	0.00e+00	1211.00
IUUC-Lch-050593	Latimeria chalumnae	92.55	0.00e+00	1206.00
IUUC-Loc-052444	Lepisosteus oculatus	90.24	0.00e+00	1231.00
IUUC-Laf-053499	Loxodonta africana	87.56	0.00e+00	1133.00
IUUC-Mcc-055038	Macaca mulatta	91.94	0.00e+00	1207.00
IUUC-Meu-056610	Macropus eugenii	90.62	0.00e+00	897.00
IUUC-Mtr-057641	Medicago truncatula	28.61	1.00e-20	94.40
IUUC-Mga-060183	Meleagris gallopavo	93.60	0.00e+00	1240.00
IUUC-Mmr-061133	Microcebus murinus	89.66	0.00e+00	1132.00
IUUC-Mdo-062312	Monodelphis domestica	92.55	0.00e+00	1217.00
IUUC-Mmu-063844	Mus musculus	91.64	0.00e+00	1176.00
IUUC-Mpu-066552	Mustela putorius furo	91.34	0.00e+00	1191.00
IUUC-Mlu-067719	Myotis lucifugus	91.64	0.00e+00	1172.00
IUUC-Nle-070045	Nomascus leucogenys	93.44	0.00e+00	1144.00
IUUC-Opr-070927	Ochotona princeps	89.40	0.00e+00	1167.00
IUUC-Ont-072680	Oreochromis niloticus	84.87	0.00e+00	1154.00
IUUC-Oan-073521	Ornithorhynchus anatinus	95.00	1.00e-52	197.00
IUUC-Ogu-077987	Oryza glumaepatula	25.43	6.00e-19	88.60
IUUC-Oru-085210	Oryza rufipogon	25.20	3.00e-19	89.70
IUUC-Ola-087454	Oryzias latipes	86.53	0.00e+00	1192.00
IUUC-Oga-088380	Otolemur garnettii	91.94	0.00e+00	1209.00
IUUC-Oar-089558	Ovis aries	74.93	0.00e+00	943.00
IUUC-Ptr-091606	Pan troglodytes	91.64	0.00e+00	1204.00
IUUC-Pan-092227	Papio anubis	91.94	0.00e+00	1207.00
IUUC-Psi-093853	Pelodiscus sinensis	86.31	0.00e+00	1021.00
IUUC-Pma-094541	Petromyzon marinus	81.33	7.00e-157	546.00
IUUC-Pfo-096237	Poecilia formosa	85.51	0.00e+00	1154.00
IUUC-Pab-097589	Pongo abelii	91.79	0.00e+00	1205.00
IUUC-Pca-100375	Procavia capensis	89.94	0.00e+00	1140.00
IUUC-Pva-102434	Pteropus vampyrus	91.79	0.00e+00	1209.00
IUUC-Rno-105443	Rattus norvegicus	91.64	0.00e+00	1177.00
IUUC-Sha-106517	Sarcophilus harrisii	92.26	0.00e+00	1212.00
IUUC-Sly-111514	Solanum lycopersicum	25.50	9.00e-18	84.30
IUUC-Stu-112646	Solanum tuberosum	26.42	3.00e-20	92.40
IUUC-Ssc-115990	Sus scrofa	91.34	0.00e+00	1204.00
IUUC-Tgu-117222	Taeniopygia guttata	93.55	0.00e+00	1233.00
IUUC-Tru-118392	Takifugu rubripes	88.74	0.00e+00	1156.00
IUUC-Tni-120220	Tetraodon nigroviridis	87.92	0.00e+00	1149.00
IUUC-Tur-126339	Triticum urartu	26.69	1.00e-17	84.30
IUUC-Tbe-128045	Tupaia belangeri	96.88	6.00e-158	550.00
IUUC-Ttr-128203	Tursiops truncatus	88.51	0.00e+00	1147.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence