iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066623

Ensembl Protein ID

ENSMPUP00000011116.1

UniProt Accession

M3YIF9; M3YIF9_MUSPF

Genbank Protein ID

ENSMPUP00000011116

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01041182

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000011208.1	ENSMPUT00000011303.1	ENSMPUP00000011116.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.20e-19	69.6	99	162
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.90e-14	51.0	198	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v+++ f+ah+ivLaa+S++F a+f++el+e+  k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 99   CDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKG-KPYVDIQGLTASTMEILLDFVYTETV 162
           9***********************************98.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 198  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 229
           89*****************************6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MMQRMLRSVD RKAQRILPTA MVRGIRPLWT MDAKKLEAPV GFLDVRGFLK TRQHPRTPFI 60
PSPYCLMGGI MAPKDIMTNT HAKSILNSMN SLRKSNTLCD VTLRVEQKDF PAHRIVLAAC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGCAGA GAATGCTGAG GTCAGTGGAT CGCAAGGCTC AGAGGATTCT CCCCACAGCC 60
ATGGTCCGCG GGATAAGGCC GTTGTGGACA ATGGACGCAA AGAAACTTGA AGCCCCCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	86.47	0.00e+00	830.00
IUUC-Apl-003339	Anas platyrhynchos	83.10	0.00e+00	737.00
IUUC-Aca-004418	Anolis carolinensis	83.23	0.00e+00	818.00
IUUC-Ame-011906	Astyanax mexicanus	61.12	9.00e-165	573.00
IUUC-Bta-012979	Bos taurus	85.45	0.00e+00	840.00
IUUC-Cja-019582	Callithrix jacchus	83.62	0.00e+00	882.00
IUUC-Cfa-020716	Canis familiaris	85.85	0.00e+00	902.00
IUUC-Cpo-022013	Cavia porcellus	86.90	0.00e+00	856.00
IUUC-Csa-023424	Chlorocebus sabaeus	86.90	0.00e+00	857.00
IUUC-Cho-024586	Choloepus hoffmanni	65.69	1.00e-174	606.00
IUUC-Dre-028344	Danio rerio	89.00	3.00e-167	580.00
IUUC-Dno-028854	Dasypus novemcinctus	87.11	0.00e+00	858.00
IUUC-Dor-030403	Dipodomys ordii	87.11	0.00e+00	857.00
IUUC-Ete-032963	Echinops telfairi	85.10	0.00e+00	721.00
IUUC-Eca-033282	Equus caballus	86.90	0.00e+00	857.00
IUUC-Fca-035487	Felis catus	87.11	0.00e+00	858.00
IUUC-Fal-037059	Ficedula albicollis	83.58	0.00e+00	815.00
IUUC-Gmo-039564	Gadus morhua	77.62	0.00e+00	780.00
IUUC-Gga-040629	Gallus gallus	83.58	0.00e+00	820.00
IUUC-Gac-042526	Gasterosteus aculeatus	78.29	0.00e+00	781.00
IUUC-Ggo-044839	Gorilla gorilla	86.90	0.00e+00	856.00
IUUC-Hsa-046742	Homo sapiens	86.90	0.00e+00	856.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	86.90	0.00e+00	854.00
IUUC-Lch-049540	Latimeria chalumnae	82.18	0.00e+00	809.00
IUUC-Loc-051923	Lepisosteus oculatus	80.92	0.00e+00	802.00
IUUC-Laf-054370	Loxodonta africana	86.69	0.00e+00	854.00
IUUC-Mcc-054852	Macaca mulatta	86.90	0.00e+00	856.00
IUUC-Mga-059486	Meleagris gallopavo	80.90	0.00e+00	703.00
IUUC-Mmr-061777	Microcebus murinus	86.46	0.00e+00	877.00
IUUC-Mdo-061990	Monodelphis domestica	85.59	0.00e+00	841.00
IUUC-Mmu-064053	Mus musculus	86.90	0.00e+00	856.00
IUUC-Mlu-067648	Myotis lucifugus	86.46	0.00e+00	877.00
IUUC-Nle-069714	Nomascus leucogenys	86.69	0.00e+00	855.00
IUUC-Opr-071143	Ochotona princeps	78.10	0.00e+00	867.00
IUUC-Ont-071848	Oreochromis niloticus	79.04	0.00e+00	786.00
IUUC-Oan-073041	Ornithorhynchus anatinus	97.15	5.00e-164	569.00
IUUC-Ocu-074379	Oryctolagus cuniculus	85.80	0.00e+00	869.00
IUUC-Ola-087469	Oryzias latipes	79.25	0.00e+00	788.00
IUUC-Oga-088004	Otolemur garnettii	99.58	5.00e-142	496.00
IUUC-Oar-090144	Ovis aries	81.38	0.00e+00	858.00
IUUC-Ptr-091406	Pan troglodytes	86.90	0.00e+00	856.00
IUUC-Pan-092762	Papio anubis	85.86	0.00e+00	839.00
IUUC-Psi-093391	Pelodiscus sinensis	83.02	0.00e+00	819.00
IUUC-Pma-094134	Petromyzon marinus	60.73	9.00e-155	540.00
IUUC-Pfo-096404	Poecilia formosa	79.17	0.00e+00	790.00
IUUC-Pab-098425	Pongo abelii	86.04	0.00e+00	843.00
IUUC-Pca-101093	Procavia capensis	100.00	2.00e-173	602.00
IUUC-Pva-102239	Pteropus vampyrus	78.22	0.00e+00	760.00
IUUC-Rno-104921	Rattus norvegicus	87.14	0.00e+00	860.00
IUUC-Sha-106625	Sarcophilus harrisii	85.66	0.00e+00	872.00
IUUC-Sar-113468	Sorex araneus	83.33	0.00e+00	681.00
IUUC-Ssc-116106	Sus scrofa	85.93	0.00e+00	907.00
IUUC-Tgu-117402	Taeniopygia guttata	78.92	0.00e+00	701.00
IUUC-Tru-117546	Takifugu rubripes	79.04	0.00e+00	785.00
IUUC-Tsy-118802	Tarsius syrichta	79.96	0.00e+00	761.00
IUUC-Tni-119999	Tetraodon nigroviridis	76.57	0.00e+00	783.00
IUUC-Tbe-127987	Tupaia belangeri	87.90	0.00e+00	850.00
IUUC-Ttr-128613	Tursiops truncatus	78.38	0.00e+00	753.00
IUUC-Xtr-132401	Xenopus tropicalis	92.23	2.00e-174	604.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence