iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	81.01	0.00e+00	1861.00	IUUC-Hsa-046040

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDPLTEEYFV SGNPGVEEQT KEETENNSEK PVSQLDKQKT DISTVPEPVN PLVEVKKVLK 60
AISALPKGVF PNIEKFIQED FSFHTVQREV TTNSQTGEEI APALTLHVLI TQLETALRNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAGCCAGCC CAACAATAAC GGGATTACTG AAGGGGACAC CCACTCGCGC CCCAAAACTC 60
CTTACCTCCA AGTGCCTCAG AAGCTGAGTG GCGTTCGCCT CCGACTTAAC GGCTTTGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033103--DZIP3
IPR013083--Znf_RING/FYVE/PHD

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0044322--C:endoplasmic reticulum quality control compartment
GO:0000836--C:Hrd1p ubiquitin ligase complex
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0051082--F:unfolded protein binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001766	Ailuropoda melanoleuca	81.11	0.00e+00	1853.00
IUUC-Bta-012849	Bos taurus	70.65	0.00e+00	763.00
IUUC-Cja-019435	Callithrix jacchus	80.58	0.00e+00	1887.00
IUUC-Cfa-020407	Canis familiaris	81.26	0.00e+00	1850.00
IUUC-Cpo-022069	Cavia porcellus	77.72	0.00e+00	1758.00
IUUC-Csa-023670	Chlorocebus sabaeus	81.18	0.00e+00	1897.00
IUUC-Cho-024981	Choloepus hoffmanni	78.23	0.00e+00	979.00
IUUC-Dno-029663	Dasypus novemcinctus	78.19	0.00e+00	1751.00
IUUC-Dor-030336	Dipodomys ordii	75.09	0.00e+00	764.00
IUUC-Ete-033022	Echinops telfairi	64.74	0.00e+00	1439.00
IUUC-Eca-033762	Equus caballus	80.66	0.00e+00	1804.00
IUUC-Eeu-034742	Erinaceus europaeus	57.44	0.00e+00	1192.00
IUUC-Fca-035996	Felis catus	79.79	0.00e+00	1815.00
IUUC-Ggo-044674	Gorilla gorilla	76.26	0.00e+00	1708.00
IUUC-Hsa-046040	Homo sapiens	81.01	0.00e+00	1866.00
IUUC-Itr-048975	Ictidomys tridecemlineatus	81.81	0.00e+00	1826.00
IUUC-Laf-054563	Loxodonta africana	79.26	0.00e+00	957.00
IUUC-Mcc-055852	Macaca mulatta	81.18	0.00e+00	1870.00
IUUC-Meu-056900	Macropus eugenii	47.40	2.00e-125	443.00
IUUC-Mmr-060578	Microcebus murinus	80.75	0.00e+00	1848.00
IUUC-Mdo-061988	Monodelphis domestica	41.88	3.00e-117	416.00
IUUC-Mmu-063804	Mus musculus	94.35	0.00e+00	2178.00
IUUC-Mpu-066754	Mustela putorius furo	81.26	0.00e+00	1877.00
IUUC-Mlu-067935	Myotis lucifugus	76.49	0.00e+00	1628.00
IUUC-Nle-069158	Nomascus leucogenys	80.66	0.00e+00	1852.00
IUUC-Opr-070900	Ochotona princeps	83.25	0.00e+00	652.00
IUUC-Ocu-074846	Oryctolagus cuniculus	79.15	0.00e+00	1756.00
IUUC-Oga-088711	Otolemur garnettii	82.62	0.00e+00	1876.00
IUUC-Oar-090116	Ovis aries	78.11	0.00e+00	1750.00
IUUC-Ptr-091540	Pan troglodytes	80.92	0.00e+00	1860.00
IUUC-Pan-092398	Papio anubis	81.35	0.00e+00	1875.00
IUUC-Pab-098081	Pongo abelii	78.40	0.00e+00	1771.00
IUUC-Pca-100213	Procavia capensis	55.00	6.00e-117	415.00
IUUC-Pva-102391	Pteropus vampyrus	71.75	0.00e+00	1571.00
IUUC-Sha-106951	Sarcophilus harrisii	42.32	6.00e-111	395.00
IUUC-Sar-113346	Sorex araneus	67.46	0.00e+00	1383.00
IUUC-Ssc-116155	Sus scrofa	80.35	0.00e+00	1531.00
IUUC-Tsy-119539	Tarsius syrichta	74.22	0.00e+00	1653.00
IUUC-Tbe-127383	Tupaia belangeri	72.85	4.00e-160	559.00
IUUC-Ttr-129021	Tursiops truncatus	80.26	0.00e+00	1821.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence