iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001615

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01044527

Gene Name

LOC100465963

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000006365.1	ENSAMET00000006994.1	ENSAMEP00000006711.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.90e-56	189.4	56	351

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl+N+g tC +N+++Q+L++   +++ l++    ++++   +e+  ++  +l  l+e++++s++kav+p el  +l+k+++    + q
   Q: 56   VGLHNIGQTCCLNCLIQVLIMNVGFTKILKR---ITVPRGT-EEQRRSVPFQLLLLLEKMQDSRQKAVQPMELAYCLQKYNVP--MFVQ 138
           6******************************...4444432.466789*********************************98..79** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da  +   + + +++++                          ++    + ++ l+ +q+ ++++clec  + sr++++l+l+lp+ +
   Q: 139  HDAAQLYLTVWNLIKDQI--------------------------TDVDLVERLQALYTIQVMESLVCLECTVERSRNSSMLTLPLPLFD 201
           ******************..........................66778899************************************9 PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +++ +++l+d+L+ f+++ el g+ k++cekc kk+  ++ lkl +lP++L++hL Rfs ++  ++ eki  +++fp++Ldls+++ +
   Q: 202  MDSKPLKTLEDALRCFFQPRELSGKSKCFCEKCGKKTCGKQVLKLIHLPQTLTIHLLRFSIRN--SQTEKICHSLYFPQSLDLSQVLLT 288
           99999******************************************************7655..7899***************96666 PP
   S: 268  peekqke....kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevlee 325
           +e+  +      ++YeL+avv H G ++ GHY+ay++n  +gkW++f+Ds+V+ v++e+++ +
   Q: 289  EEDLCNAeeqlGRQYELFAVVAHVGAADFGHYCAYIQNsVDGKWFCFNDSNVSWVSWEDIQCT 351
           4433333466699*************************45677****************9975 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

NESGVGVPEG ICQCILAESQ HFSAEPIEKK EENNMKRKKE QLRERISAWD CPHGPVGLHN 60
IGQTCCLNCL IQVLIMNVGF TKILKRITVP RGTEEQRRSV PFQLLLLLEK MQDSRQKAVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGAGTCAG GTGTTGGGGT CCCTGAGGGA ATTTGCCAGT GCATCCTGGC TGAGTCTCAG 60
CATTTCTCAG CAGAACCCAT TGAGAAGAAG GAAGAGAACA ACATGAAGCG GAAGAAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004006	Anas platyrhynchos	56.96	1.00e-102	366.00
IUUC-Aca-005088	Anolis carolinensis	52.41	1.00e-82	300.00
IUUC-Ame-010606	Astyanax mexicanus	33.45	1.00e-39	156.00
IUUC-Bta-013036	Bos taurus	80.72	1.00e-150	525.00
IUUC-Cja-019052	Callithrix jacchus	75.16	4.00e-135	474.00
IUUC-Cfa-020554	Canis familiaris	95.38	0.00e+00	648.00
IUUC-Cpo-022421	Cavia porcellus	71.51	2.00e-146	511.00
IUUC-Csa-023737	Chlorocebus sabaeus	77.78	2.00e-87	314.00
IUUC-Cho-024807	Choloepus hoffmanni	70.05	2.00e-71	262.00
IUUC-Dre-027408	Danio rerio	32.26	4.00e-43	168.00
IUUC-Dno-029813	Dasypus novemcinctus	66.57	3.00e-119	421.00
IUUC-Dor-030532	Dipodomys ordii	76.15	7.00e-157	546.00
IUUC-Ete-032254	Echinops telfairi	70.49	1.00e-144	506.00
IUUC-Eca-033482	Equus caballus	87.91	8.00e-163	565.00
IUUC-Eeu-034451	Erinaceus europaeus	76.77	1.00e-91	328.00
IUUC-Fca-036313	Felis catus	93.56	0.00e+00	660.00
IUUC-Fal-037216	Ficedula albicollis	51.73	1.00e-98	352.00
IUUC-Gmo-038649	Gadus morhua	33.56	4.00e-38	151.00
IUUC-Gga-041082	Gallus gallus	55.24	2.00e-90	325.00
IUUC-Gac-042439	Gasterosteus aculeatus	36.33	9.00e-48	183.00
IUUC-Ggo-044957	Gorilla gorilla	81.25	2.00e-133	468.00
IUUC-Hsa-046381	Homo sapiens	78.15	9.00e-165	572.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	77.18	4.00e-160	557.00
IUUC-Loc-052688	Lepisosteus oculatus	31.19	2.00e-42	166.00
IUUC-Laf-054109	Loxodonta africana	78.71	1.00e-168	585.00
IUUC-Mcc-054814	Macaca mulatta	77.18	9.00e-165	572.00
IUUC-Meu-056253	Macropus eugenii	68.06	9.00e-110	389.00
IUUC-Mmr-061613	Microcebus murinus	79.69	5.00e-156	543.00
IUUC-Mdo-061890	Monodelphis domestica	66.56	8.00e-125	439.00
IUUC-Mmu-064329	Mus musculus	70.79	7.00e-143	499.00
IUUC-Mpu-066342	Mustela putorius furo	94.71	0.00e+00	682.00
IUUC-Mlu-067010	Myotis lucifugus	81.34	2.00e-178	618.00
IUUC-Nle-069148	Nomascus leucogenys	76.55	4.00e-160	557.00
IUUC-Opr-070988	Ochotona princeps	68.46	2.00e-60	226.00
IUUC-Ont-072039	Oreochromis niloticus	33.77	3.00e-45	175.00
IUUC-Oan-073740	Ornithorhynchus anatinus	58.65	2.00e-73	268.00
IUUC-Ocu-074498	Oryctolagus cuniculus	77.68	3.00e-146	511.00
IUUC-Ola-086753	Oryzias latipes	35.33	3.00e-47	182.00
IUUC-Oga-088497	Otolemur garnettii	79.66	9.00e-170	589.00
IUUC-Oar-089505	Ovis aries	79.41	5.00e-148	516.00
IUUC-Ptr-091656	Pan troglodytes	77.59	5.00e-164	570.00
IUUC-Pan-092498	Papio anubis	77.46	2.00e-164	571.00
IUUC-Psi-093409	Pelodiscus sinensis	52.17	6.00e-101	360.00
IUUC-Pfo-096507	Poecilia formosa	36.24	7.00e-47	180.00
IUUC-Pab-097828	Pongo abelii	79.94	2.00e-148	518.00
IUUC-Pca-100299	Procavia capensis	74.37	2.00e-100	358.00
IUUC-Pva-102972	Pteropus vampyrus	81.38	9.00e-166	575.00
IUUC-Rno-105738	Rattus norvegicus	69.38	2.00e-145	508.00
IUUC-Sha-107309	Sarcophilus harrisii	64.60	1.00e-119	422.00
IUUC-Sar-112983	Sorex araneus	68.41	4.00e-125	440.00
IUUC-Ssc-116049	Sus scrofa	83.33	3.00e-156	543.00
IUUC-Tgu-117115	Taeniopygia guttata	54.43	4.00e-96	344.00
IUUC-Tru-118022	Takifugu rubripes	32.78	6.00e-39	154.00
IUUC-Tsy-118986	Tarsius syrichta	65.33	2.00e-63	236.00
IUUC-Tni-120306	Tetraodon nigroviridis	33.00	2.00e-38	152.00
IUUC-Tbe-127768	Tupaia belangeri	70.41	2.00e-113	402.00
IUUC-Ttr-128686	Tursiops truncatus	75.66	2.00e-150	525.00
IUUC-Xtr-132032	Xenopus tropicalis	43.97	4.00e-68	251.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence