iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054648

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase NHLRC1

Genbank Nucleotide ID

JSUE03030351

Gene Name

NHLRC1; EGK_14504

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000016626.2	ENSMMUT00000023366.2	ENSMMUP00000021863.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.23	0.00e+00	707.00	IUUC-Hsa-046346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAAEASESEP ALQELMREAE ISLLECKVCF EKFGHRQQRR PRNLSCGHVV CLACVAALAH 60
PRTLALECPF CRRACRGCDT SDCLPVLHLI ELLGSALRQS PAAHRAAPSA PGALTCHHTF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCG AAGCCTCGGA GAGCGAACCG GCTCTGCAGG AGCTCATGCG CGAGGCGGAG 60
ATCAGCCTGC TGGAGTGCAA GGTGTGCTTT GAGAAGTTTG GCCACCGGCA GCAGCGGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR013017--NHL_repeat_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51125--NHL
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF14634--zf-RING_5

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0031398--P:positive regulation of protein ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

mcc:704451

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003482	Anas platyrhynchos	50.74	1.00e-60	225.00
IUUC-Aca-004781	Anolis carolinensis	55.28	2.00e-133	468.00
IUUC-Ame-011442	Astyanax mexicanus	42.58	6.00e-82	298.00
IUUC-Bta-013205	Bos taurus	86.62	0.00e+00	647.00
IUUC-Cfa-020810	Canis familiaris	88.42	7.00e-175	606.00
IUUC-Cpo-022053	Cavia porcellus	75.99	4.00e-126	444.00
IUUC-Csa-023522	Chlorocebus sabaeus	98.99	0.00e+00	714.00
IUUC-Dno-029008	Dasypus novemcinctus	80.51	6.00e-169	586.00
IUUC-Ete-032878	Echinops telfairi	80.12	8.00e-48	184.00
IUUC-Eca-034419	Equus caballus	89.54	0.00e+00	649.00
IUUC-Eeu-034990	Erinaceus europaeus	79.95	3.00e-169	587.00
IUUC-Fca-035755	Felis catus	89.77	0.00e+00	665.00
IUUC-Fal-036689	Ficedula albicollis	55.00	3.00e-43	167.00
IUUC-Fox-037671	Fusarium oxysporum	43.86	4.00e-06	45.10
IUUC-Gmo-038749	Gadus morhua	40.05	1.00e-66	246.00
IUUC-Gga-040860	Gallus gallus	53.15	6.00e-102	364.00
IUUC-Gac-041602	Gasterosteus aculeatus	42.25	1.00e-76	280.00
IUUC-Ggo-044705	Gorilla gorilla	94.43	0.00e+00	697.00
IUUC-Hsa-046346	Homo sapiens	98.23	0.00e+00	706.00
IUUC-Itr-048387	Ictidomys tridecemlineatus	85.42	2.00e-179	621.00
IUUC-Lch-049978	Latimeria chalumnae	46.89	7.00e-101	360.00
IUUC-Loc-051893	Lepisosteus oculatus	47.63	2.00e-93	336.00
IUUC-Meu-056176	Macropus eugenii	67.51	9.00e-146	509.00
IUUC-Mvi-060410	Microbotryum violaceum	30.99	3.30e-02	33.10
IUUC-Mmr-061462	Microcebus murinus	91.14	0.00e+00	649.00
IUUC-Mdo-062329	Monodelphis domestica	67.91	2.00e-156	545.00
IUUC-Mmu-063514	Mus musculus	83.55	6.00e-172	596.00
IUUC-Mac-064583	Musa acuminata	25.81	4.70e-02	33.50
IUUC-Mpu-066828	Mustela putorius furo	87.86	6.00e-178	616.00
IUUC-Nle-069194	Nomascus leucogenys	97.22	0.00e+00	726.00
IUUC-Opr-070547	Ochotona princeps	83.46	6.00e-180	623.00
IUUC-Ont-071588	Oreochromis niloticus	41.49	2.00e-74	272.00
IUUC-Oan-073550	Ornithorhynchus anatinus	53.15	2.00e-107	382.00
IUUC-Ocu-074699	Oryctolagus cuniculus	83.16	0.00e+00	632.00
IUUC-Ola-087036	Oryzias latipes	42.04	1.00e-78	286.00
IUUC-Oga-088924	Otolemur garnettii	90.89	0.00e+00	651.00
IUUC-Oar-089939	Ovis aries	82.26	4.00e-118	417.00
IUUC-Ptr-091431	Pan troglodytes	98.23	0.00e+00	706.00
IUUC-Pan-092496	Papio anubis	99.49	0.00e+00	718.00
IUUC-Psi-094079	Pelodiscus sinensis	57.39	3.00e-134	471.00
IUUC-Pab-097605	Pongo abelii	97.47	0.00e+00	700.00
IUUC-Pca-100676	Procavia capensis	79.50	5.00e-179	620.00
IUUC-Pva-102804	Pteropus vampyrus	89.11	0.00e+00	677.00
IUUC-Rno-104999	Rattus norvegicus	83.08	1.00e-173	602.00
IUUC-Sha-107067	Sarcophilus harrisii	67.75	3.00e-151	528.00
IUUC-Tgu-116560	Taeniopygia guttata	50.71	2.00e-40	157.00
IUUC-Tru-117560	Takifugu rubripes	41.09	5.00e-63	234.00
IUUC-Tni-120569	Tetraodon nigroviridis	42.16	5.00e-74	271.00
IUUC-Ttr-129122	Tursiops truncatus	89.62	0.00e+00	645.00
IUUC-Xtr-132226	Xenopus tropicalis	46.21	3.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence