iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003284

Ensembl Protein ID

ENSAPLP00000004546.1

UniProt Accession

U3IBC4; U3IBC4_ANAPL

Genbank Protein ID

ENSAPLP00000004546

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01053388

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000004912.1	ENSAPLT00000005162.1	ENSAPLP00000004546.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-69	234.3	1762	2107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1762 VGLTNLGATCYLASTIQQLYMIPEARQAIFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1841
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1842 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 1900
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 1901 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 1982
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                +  k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 1983 MTPYTEDflmgkndrkegfkedgEYLKETESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2069
           *******999998888888888755566669**************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2070 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2107
           7779********************************96 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

RRSLQRTLML LAYGALMRRK SCCCVWQKFQ IQFPLYTAYK HNTHPTIEDI SAQESNILGA 60
FCDMNDVEVP LHLLRYVCLF CGKNGLSLMK DCFEYGTPET LPFLIAHAFI TVVSNIRIWL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAGGAGTC TGCAAAGAAC ACTGATGCTT TTAGCTTATG GAGCACTGAT GAGAAGGAAA 60
AGTTGTTGCT GTGTGTGGCA AAAATCTTTC AGATTCAGTT TCCTCTGTAC ACTGCTTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR011030--Vitellinogen_superhlx

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	95.09	0.00e+00	6350.00
IUUC-Aca-004415	Anolis carolinensis	95.58	0.00e+00	6366.00
IUUC-Acl-008140	Aspergillus clavatus	28.87	6.00e-64	240.00
IUUC-Afl-008381	Aspergillus flavus	29.04	2.00e-63	238.00
IUUC-Afu-008857	Aspergillus fumigatus	28.48	8.00e-65	243.00
IUUC-Ani-009257	Aspergillus nidulans	27.42	1.00e-55	213.00
IUUC-Ang-009759	Aspergillus niger	27.89	5.00e-63	237.00
IUUC-Aor-009931	Aspergillus oryzae	29.04	2.00e-63	238.00
IUUC-Ate-010246	Aspergillus terreus	29.51	3.00e-53	204.00
IUUC-Ame-011219	Astyanax mexicanus	65.32	0.00e+00	2491.00
IUUC-Bgr-012195	Blumeria graminis	27.04	2.00e-65	245.00
IUUC-Bta-012989	Bos taurus	94.55	0.00e+00	6287.00
IUUC-Bci-013798	Botrytis cinerea	33.17	4.00e-58	221.00
IUUC-Cja-018974	Callithrix jacchus	90.85	0.00e+00	772.00
IUUC-Cfa-021214	Canis familiaris	95.06	0.00e+00	6352.00
IUUC-Cpo-021912	Cavia porcellus	94.57	0.00e+00	4310.00
IUUC-Csa-023658	Chlorocebus sabaeus	94.71	0.00e+00	6303.00
IUUC-Cho-024971	Choloepus hoffmanni	81.17	0.00e+00	3105.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	28.84	4.00e-64	241.00
IUUC-Dre-027428	Danio rerio	86.34	0.00e+00	4686.00
IUUC-Dno-029690	Dasypus novemcinctus	94.26	0.00e+00	6257.00
IUUC-Dor-030817	Dipodomys ordii	85.66	0.00e+00	2078.00
IUUC-Dse-031423	Dothistroma septosporum	25.78	1.00e-36	149.00
IUUC-Dme-032102	Drosophila melanogaster	54.27	0.00e+00	853.00
IUUC-Ete-032552	Echinops telfairi	91.45	0.00e+00	2921.00
IUUC-Eca-033457	Equus caballus	95.12	0.00e+00	6344.00
IUUC-Eeu-035118	Erinaceus europaeus	91.44	0.00e+00	2992.00
IUUC-Fca-036213	Felis catus	93.53	0.00e+00	4938.00
IUUC-Fal-037643	Ficedula albicollis	96.21	0.00e+00	6378.00
IUUC-Fox-037971	Fusarium oxysporum	27.54	2.00e-62	234.00
IUUC-Fso-038108	Fusarium solani	27.38	3.00e-59	224.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.16	4.00e-61	231.00
IUUC-Gga-040511	Gallus gallus	96.41	0.00e+00	6443.00
IUUC-Gac-042024	Gasterosteus aculeatus	91.18	0.00e+00	4334.00
IUUC-Ggo-044924	Gorilla gorilla	90.98	0.00e+00	6054.00
IUUC-Hsa-046913	Homo sapiens	94.71	0.00e+00	6332.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	94.67	0.00e+00	6336.00
IUUC-Lch-049675	Latimeria chalumnae	88.61	0.00e+00	4766.00
IUUC-Loc-052832	Lepisosteus oculatus	89.23	0.00e+00	5872.00
IUUC-Lma-053130	Leptosphaeria maculans	27.30	3.00e-59	224.00
IUUC-Laf-054169	Loxodonta africana	93.95	0.00e+00	6312.00
IUUC-Mcc-055847	Macaca mulatta	93.80	0.00e+00	6217.00
IUUC-Meu-056327	Macropus eugenii	86.05	0.00e+00	1577.00
IUUC-Mor-057152	Magnaporthe oryzae	28.15	5.00e-61	230.00
IUUC-Mpo-057310	Magnaporthe poae	26.58	7.00e-60	226.00
IUUC-Mmr-060780	Microcebus murinus	94.95	0.00e+00	6341.00
IUUC-Mdo-062308	Monodelphis domestica	93.51	0.00e+00	6210.00
IUUC-Mmu-063457	Mus musculus	93.14	0.00e+00	6252.00
IUUC-Mpu-066917	Mustela putorius furo	92.69	0.00e+00	6127.00
IUUC-Mlu-067696	Myotis lucifugus	94.77	0.00e+00	6311.00
IUUC-Nfi-068259	Neosartorya fischeri	27.72	4.00e-64	241.00
IUUC-Ncr-068911	Neurospora crassa	25.85	4.00e-59	224.00
IUUC-Nle-069586	Nomascus leucogenys	94.56	0.00e+00	6355.00
IUUC-Opr-070447	Ochotona princeps	90.68	0.00e+00	2798.00
IUUC-Ont-072396	Oreochromis niloticus	84.22	0.00e+00	5413.00
IUUC-Oan-073147	Ornithorhynchus anatinus	95.86	0.00e+00	6402.00
IUUC-Ocu-074324	Oryctolagus cuniculus	94.42	0.00e+00	6292.00
IUUC-Ola-086312	Oryzias latipes	83.18	0.00e+00	5330.00
IUUC-Oga-088878	Otolemur garnettii	94.68	0.00e+00	6331.00
IUUC-Oar-089919	Ovis aries	94.64	0.00e+00	6297.00
IUUC-Ptr-090713	Pan troglodytes	95.12	0.00e+00	5821.00
IUUC-Pan-091957	Papio anubis	95.77	0.00e+00	4994.00
IUUC-Psi-093240	Pelodiscus sinensis	96.75	0.00e+00	6454.00
IUUC-Pma-094469	Petromyzon marinus	74.00	0.00e+00	4120.00
IUUC-Pno-095059	Phaeosphaeria nodorum	28.76	3.00e-56	214.00
IUUC-Pfo-097159	Poecilia formosa	85.33	0.00e+00	5455.00
IUUC-Pab-098003	Pongo abelii	94.15	0.00e+00	6291.00
IUUC-Pca-100799	Procavia capensis	95.77	0.00e+00	1469.00
IUUC-Pva-103226	Pteropus vampyrus	90.16	0.00e+00	5923.00
IUUC-Pte-104235	Pyrenophora teres	32.86	6.00e-59	223.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.32	7.00e-60	226.00
IUUC-Rno-105389	Rattus norvegicus	93.45	0.00e+00	5403.00
IUUC-Sha-106979	Sarcophilus harrisii	95.49	0.00e+00	6348.00
IUUC-Sar-113444	Sorex araneus	87.90	0.00e+00	5778.00
IUUC-Ssc-115815	Sus scrofa	94.65	0.00e+00	5220.00
IUUC-Tgu-117470	Taeniopygia guttata	98.16	0.00e+00	6522.00
IUUC-Tru-118543	Takifugu rubripes	83.08	0.00e+00	5410.00
IUUC-Tsy-119081	Tarsius syrichta	86.00	0.00e+00	4757.00
IUUC-Tni-120294	Tetraodon nigroviridis	86.78	3.00e-165	574.00
IUUC-Tre-122057	Trichoderma reesei	32.79	6.00e-60	227.00
IUUC-Tvi-122570	Trichoderma virens	35.62	6.00e-59	223.00
IUUC-Tme-127154	Tuber melanosporum	28.18	8.00e-61	228.00
IUUC-Tbe-127801	Tupaia belangeri	89.22	0.00e+00	2884.00
IUUC-Ttr-129262	Tursiops truncatus	90.45	0.00e+00	5957.00
IUUC-Vda-129686	Verticillium dahliae	28.55	8.00e-61	229.00
IUUC-Vpa-130484	Vicugna pacos	93.16	0.00e+00	5156.00
IUUC-Xtr-131769	Xenopus tropicalis	88.10	0.00e+00	5927.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence