iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000001547.3	ENSMMUT00000057898.1	ENSMMUP00000048025.1
ENSMMUG00000001547.3	ENSMMUT00000075770.1	ENSMMUP00000043216.1
ENSMMUG00000001547.3	ENSMMUT00000002187.3	ENSMMUP00000002066.3
ENSMMUG00000001547.3	ENSMMUT00000002185.3	ENSMMUP00000002064.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-19	69.3	1569	1609
UBD/Beta-Prp	1.20e-51	176.7	1524	1725

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtl...lvsGsdDgtikvWDlrtgvll 36
           gHt++v+cl     s+     l +Gs D+t++++++++  ++
   Q: 1569 GHTSKVNCLLVtqtSG-KnaaLYTGSSDHTVRCYNVKSRECV 1609
           8*******95587533.24579**************988876 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqc 128
             s++gh+a+v+a+++  +  +l t+s D+t++v++l ++kcv +++gh+++v +l + +   ++  l +Gs+d t+r++++++++c
   Q: 1524 EGSFEGHQAAVNAIQIFGN--LLYTCSADKTVRVYNLVSRKCVGVFEGHTSKVNCLLVTQtsgKNAALYTGSSDHTVRCYNVKSREC 1608
           6789*************99..9*********************************99999755558899****************** PP
   S: 129  leetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtge 213
           +e  l+ +d   +++++h+  ++l +G +++tv  +++k++k l+ ++    ++v +l+  ++g  k lv gs+d t+ + d ++g 
   Q: 1609 VE-QLQLED---RVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEGarKLLVVGSYDCTISVRDARNGL 1691
           *9.777777...566677767**************************9977899999**99999999******************** PP
   S: 214  cvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
            +rtl+gh+++++++++   ++++ sgssD+s+  +
   Q: 1692 LLRTLEGHSKTILCMKVV--NDLVFSGSSDQSVHAH 1725
           ******************..9***********9876 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPVGRIECPS SPSFPRDISH ECRVCGVTEV GLSAYAKHIS GQLHKDNVDA QEREDDGKGE 60
EEEEDYFDKE LVQLIKQRKE QSRQDEPSNS NQEINSDDRR PQWRREDRIP YQDRESYSQP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGATTATTG AAAACGGCGG ACCGCAAAGG ANAAAAAAAA AAAGAGCGTG ACGGCCTCGG 60
TGTGCGCCTG CGCGCTGGCG GCGGCTGTGG CGGGGCCCGG CGGGGAGCGG GTCCGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00320--WD40
SM00355--ZnF_C2H2

Gene Ontology

GO:0046872--F:metal ion binding
GO:0003723--F:RNA binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001928	Ailuropoda melanoleuca	87.52	0.00e+00	3136.00
IUUC-Apl-003674	Anas platyrhynchos	56.79	0.00e+00	1696.00
IUUC-Aca-005018	Anolis carolinensis	53.65	0.00e+00	1637.00
IUUC-Ame-011431	Astyanax mexicanus	68.95	0.00e+00	683.00
IUUC-Bta-013436	Bos taurus	87.11	0.00e+00	3043.00
IUUC-Cfa-020278	Canis familiaris	86.42	0.00e+00	2575.00
IUUC-Cpo-022278	Cavia porcellus	80.21	0.00e+00	2779.00
IUUC-Csa-023115	Chlorocebus sabaeus	98.85	0.00e+00	2160.00
IUUC-Cho-024829	Choloepus hoffmanni	82.10	0.00e+00	2217.00
IUUC-Dre-028112	Danio rerio	65.39	0.00e+00	667.00
IUUC-Dno-029127	Dasypus novemcinctus	84.71	0.00e+00	2933.00
IUUC-Dor-030367	Dipodomys ordii	80.72	0.00e+00	1200.00
IUUC-Ete-032500	Echinops telfairi	73.80	0.00e+00	1276.00
IUUC-Eca-034319	Equus caballus	88.30	0.00e+00	3075.00
IUUC-Eeu-034754	Erinaceus europaeus	76.96	0.00e+00	2397.00
IUUC-Fca-036181	Felis catus	88.00	0.00e+00	3053.00
IUUC-Fal-036865	Ficedula albicollis	55.81	0.00e+00	1587.00
IUUC-Gmo-039227	Gadus morhua	64.47	3.00e-175	608.00
IUUC-Gga-041178	Gallus gallus	56.96	0.00e+00	1734.00
IUUC-Gac-042209	Gasterosteus aculeatus	64.56	6.00e-168	584.00
IUUC-Ggo-044636	Gorilla gorilla	95.46	0.00e+00	3427.00
IUUC-Hsa-045949	Homo sapiens	97.24	0.00e+00	3475.00
IUUC-Itr-048628	Ictidomys tridecemlineatus	88.49	0.00e+00	3138.00
IUUC-Lch-049753	Latimeria chalumnae	49.77	0.00e+00	1419.00
IUUC-Loc-052333	Lepisosteus oculatus	69.19	0.00e+00	730.00
IUUC-Laf-053530	Loxodonta africana	83.45	0.00e+00	3003.00
IUUC-Meu-056609	Macropus eugenii	67.22	0.00e+00	1235.00
IUUC-Mga-059632	Meleagris gallopavo	57.21	0.00e+00	1696.00
IUUC-Mmr-060742	Microcebus murinus	89.38	0.00e+00	3160.00
IUUC-Mdo-061831	Monodelphis domestica	82.10	0.00e+00	1325.00
IUUC-Mmu-064055	Mus musculus	76.87	0.00e+00	2545.00
IUUC-Mpu-066458	Mustela putorius furo	91.83	0.00e+00	1566.00
IUUC-Mlu-067767	Myotis lucifugus	84.44	0.00e+00	2933.00
IUUC-Nle-069728	Nomascus leucogenys	96.87	0.00e+00	3459.00
IUUC-Opr-070914	Ochotona princeps	79.85	0.00e+00	2762.00
IUUC-Ont-072462	Oreochromis niloticus	56.96	5.00e-162	565.00
IUUC-Ocu-073827	Oryctolagus cuniculus	86.57	0.00e+00	2974.00
IUUC-Ola-087573	Oryzias latipes	67.96	2.00e-162	566.00
IUUC-Oga-088664	Otolemur garnettii	89.46	0.00e+00	1865.00
IUUC-Oar-090256	Ovis aries	84.13	0.00e+00	2349.00
IUUC-Ptr-090884	Pan troglodytes	95.83	0.00e+00	2915.00
IUUC-Pan-091779	Papio anubis	99.34	0.00e+00	2175.00
IUUC-Psi-093267	Pelodiscus sinensis	93.09	1.00e-165	575.00
IUUC-Pma-094414	Petromyzon marinus	43.49	9.00e-59	222.00
IUUC-Pfo-097009	Poecilia formosa	63.99	4.00e-159	556.00
IUUC-Pca-100820	Procavia capensis	78.73	0.00e+00	2187.00
IUUC-Pva-103044	Pteropus vampyrus	80.52	0.00e+00	1217.00
IUUC-Rno-105960	Rattus norvegicus	71.58	0.00e+00	2339.00
IUUC-Sar-113018	Sorex araneus	74.90	0.00e+00	1333.00
IUUC-Ssc-115278	Sus scrofa	87.16	0.00e+00	3058.00
IUUC-Tgu-117231	Taeniopygia guttata	55.26	0.00e+00	1622.00
IUUC-Tru-118472	Takifugu rubripes	55.34	5.00e-165	575.00
IUUC-Tsy-118877	Tarsius syrichta	85.66	0.00e+00	2100.00
IUUC-Tni-119881	Tetraodon nigroviridis	56.87	4.00e-178	619.00
IUUC-Tbe-127499	Tupaia belangeri	80.90	0.00e+00	1613.00
IUUC-Ttr-128962	Tursiops truncatus	88.21	0.00e+00	3052.00
IUUC-Vpa-130089	Vicugna pacos	82.09	0.00e+00	1342.00
IUUC-Xtr-132940	Xenopus tropicalis	46.73	0.00e+00	1319.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence