iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
iRefIndex
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	21338947

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	0.00052	20.8	7	41

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknsss 37
           C iC   f+d p++l CgH  ++ C  k  ++++ ss
   Q: 7    CTICIRFFED-PIILTCGHSLCRMCALKA-HQPSTSS 41
           **********.999***********8555.2333333 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MEEELKCTIC IRFFEDPIIL TCGHSLCRMC ALKAHQPSTS SGSSSTSSPR PSTPGILSQI 60
LSSASSPISP QSAGSSSGAS DTMSLCVSDN GDHESDKLSV VSETDSGVVG CGRTSRPSSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCTTCAAA AATGGAGGAA GAGCTCAAAT GCACAATATG CATTCGATTT TTCGAAGACC 60
CCATCATTCT TACCTGCGGC CACAGTCTCT GCAGAATGTG CGCCCTGAAA GCCCACCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50853--FN3
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF00097--zf-C3HC4

SMART

SM00502--BBC
SM00336--BBOX
SM00060--FN3
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0031252--C:cell leading edge
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0055120--C:striated muscle dense body
GO:0042803--F:protein homodimerization activity
GO:0005102--F:receptor binding
GO:0008270--F:zinc ion binding
GO:0030031--P:cell projection assembly
GO:0033563--P:dorsal/ventral axon guidance
GO:0031175--P:neuron projection development

KEGG

cel:CELE_C39F7.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002033	Ailuropoda melanoleuca	41.94	8.00e-104	369.00
IUUC-Apl-004004	Anas platyrhynchos	42.15	1.00e-133	468.00
IUUC-Aca-004773	Anolis carolinensis	39.51	1.00e-128	452.00
IUUC-Ame-011429	Astyanax mexicanus	33.07	1.00e-111	395.00
IUUC-Bta-013184	Bos taurus	36.80	6.00e-145	506.00
IUUC-Cja-019517	Callithrix jacchus	41.71	3.00e-128	451.00
IUUC-Cfa-020240	Canis familiaris	39.79	3.00e-126	444.00
IUUC-Cpo-022321	Cavia porcellus	42.44	2.00e-131	461.00
IUUC-Csa-024114	Chlorocebus sabaeus	35.08	7.00e-132	463.00
IUUC-Cho-024399	Choloepus hoffmanni	44.17	4.00e-66	244.00
IUUC-Cin-025387	Ciona intestinalis	36.94	9.00e-118	416.00
IUUC-Csv-025851	Ciona savignyi	33.62	5.00e-128	450.00
IUUC-Dre-027691	Danio rerio	37.61	4.00e-147	513.00
IUUC-Dno-029047	Dasypus novemcinctus	37.32	3.00e-145	508.00
IUUC-Dor-030823	Dipodomys ordii	29.68	9.00e-63	233.00
IUUC-Dme-031822	Drosophila melanogaster	42.81	1.00e-148	518.00
IUUC-Ete-032674	Echinops telfairi	38.30	2.00e-111	395.00
IUUC-Eca-034107	Equus caballus	35.61	1.00e-131	462.00
IUUC-Eeu-034755	Erinaceus europaeus	47.81	6.00e-65	240.00
IUUC-Fca-036046	Felis catus	33.89	5.00e-86	310.00
IUUC-Fal-036997	Ficedula albicollis	41.77	5.00e-113	400.00
IUUC-Gmo-039639	Gadus morhua	34.22	6.00e-118	416.00
IUUC-Gga-040951	Gallus gallus	37.09	1.00e-142	499.00
IUUC-Gac-041390	Gasterosteus aculeatus	34.79	4.00e-125	440.00
IUUC-Ggo-044878	Gorilla gorilla	40.07	3.00e-126	444.00
IUUC-Hsa-046503	Homo sapiens	37.45	5.00e-146	509.00
IUUC-Itr-047884	Ictidomys tridecemlineatus	35.65	4.00e-135	474.00
IUUC-Lch-049521	Latimeria chalumnae	30.16	6.00e-98	350.00
IUUC-Loc-052458	Lepisosteus oculatus	36.73	3.00e-139	488.00
IUUC-Laf-054442	Loxodonta africana	37.58	3.00e-145	507.00
IUUC-Mcc-054887	Macaca mulatta	37.58	1.00e-145	508.00
IUUC-Meu-056251	Macropus eugenii	32.72	8.00e-79	287.00
IUUC-Mga-059961	Meleagris gallopavo	42.13	1.00e-110	392.00
IUUC-Mmr-061677	Microcebus murinus	37.32	3.00e-145	507.00
IUUC-Mdo-062608	Monodelphis domestica	40.44	5.00e-114	404.00
IUUC-Mmu-064150	Mus musculus	34.77	2.00e-133	468.00
IUUC-Mpu-065904	Mustela putorius furo	40.28	5.00e-127	447.00
IUUC-Mlu-067137	Myotis lucifugus	37.71	1.00e-146	512.00
IUUC-Nle-070127	Nomascus leucogenys	37.71	4.00e-146	510.00
IUUC-Opr-070450	Ochotona princeps	40.45	2.00e-119	422.00
IUUC-Ont-071416	Oreochromis niloticus	37.98	5.00e-146	510.00
IUUC-Oan-073661	Ornithorhynchus anatinus	44.83	3.00e-59	219.00
IUUC-Ocu-074651	Oryctolagus cuniculus	40.00	1.00e-126	446.00
IUUC-Ola-086349	Oryzias latipes	45.24	5.00e-52	196.00
IUUC-Oga-088823	Otolemur garnettii	40.07	1.00e-125	442.00
IUUC-Oar-089807	Ovis aries	36.67	2.00e-141	494.00
IUUC-Ptr-091267	Pan troglodytes	40.07	3.00e-126	444.00
IUUC-Pan-092803	Papio anubis	34.86	2.00e-128	452.00
IUUC-Psi-093885	Pelodiscus sinensis	42.64	7.00e-117	412.00
IUUC-Pma-094534	Petromyzon marinus	25.33	4.00e-12	63.90
IUUC-Pfo-096684	Poecilia formosa	37.04	3.00e-144	504.00
IUUC-Pab-097638	Pongo abelii	37.71	2.00e-145	508.00
IUUC-Pca-101102	Procavia capensis	34.91	4.00e-95	341.00
IUUC-Pva-103059	Pteropus vampyrus	32.71	1.00e-85	310.00
IUUC-Rno-105306	Rattus norvegicus	37.45	3.00e-142	497.00
IUUC-Sha-106771	Sarcophilus harrisii	41.70	3.00e-113	400.00
IUUC-Sar-113278	Sorex araneus	39.51	1.00e-114	405.00
IUUC-Ssc-115634	Sus scrofa	37.32	9.00e-146	509.00
IUUC-Tgu-117319	Taeniopygia guttata	40.87	3.00e-125	440.00
IUUC-Tru-117583	Takifugu rubripes	37.68	2.00e-143	501.00
IUUC-Tsy-119427	Tarsius syrichta	30.63	7.00e-59	220.00
IUUC-Tni-120847	Tetraodon nigroviridis	37.86	1.00e-144	505.00
IUUC-Tbe-127239	Tupaia belangeri	32.61	2.00e-81	295.00
IUUC-Ttr-128462	Tursiops truncatus	36.83	3.00e-75	273.00
IUUC-Vpa-130241	Vicugna pacos	33.73	2.00e-85	309.00
IUUC-Xtr-131998	Xenopus tropicalis	36.90	2.00e-140	491.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence