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Tag Content
iUUCD ID IUUC-Afu-008958
Ensembl Protein ID CADAFUAP00003073
UniProt Accession Q4WC55; MYO1_ASPFU
Genbank Protein ID EAL85329.1
Protein Name Myosin-1; Class I unconventional myosin; Type I myosin
Genbank Nucleotide ID AAHF01000013
Gene Name AFUA_8G05660; myoA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADAFUAG00003073 CADAFUAT00003073 CADAFUAP00003073
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 4.80e-12 44.6 1098 1152
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + +vlyd+++q+++eL++k+G++v+++   ++ +gW+ + + ++  +G  Pe + e+
   Q: 1098 TAKVLYDFNSQQSNELSIKAGEIVQIV--SKEGNGWWLCMNMTTSAQGWTPEAYLEE 1152
           679************************..67788******************99875 PP
   
Organism Aspergillus fumigatus
Functional Description
(View)

Functional Description


     Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
 Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
Protein Sequence
(Fasta)
MSTVNPHNQL QMKLFLTQKG HSRRPAGGEK KSRGFGRSKA VADVGDGRQT GGKPQVKKAT 60
FESTKKKEIG VSDLTLLSKI SNEAINDNLK LRFEHDEIYT YIGHVLVSVN PFRDLGIYTD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Afu-008958|UBD,SH3|Aspergillus fumigatus
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Nucleotide Sequence
(Fasta)
ATGTCTACAG TTAACCCTCA CAATCAGCTT CAGATGAAAT TGTTCTTGAC TCAGAAAGTG 60
TGTTCTAACT CGGCGCTTTT TTTTAGGGAC ACTCACGACG TCCTGCTGGC GGAGAGAAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Afu-008958|UBD,SH3|Aspergillus fumigatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0378--Hydrolase
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
Interpro

IPR001609--Myosin_head_motor_dom
IPR010926--Myosin_TH1
IPR027417--P-loop_NTPase
IPR001452--SH3_domain
PROSITE

PS51456--MYOSIN_MOTOR
PS50002--SH3
PS51757--TH1
Pfam

PF00063--Myosin_head
PF06017--Myosin_TH1
PF00018--SH3_1
PRINTS

PR00193--MYOSINHEAVY
SMART

SM00242--MYSc
SM00326--SH3
Gene Ontology

GO:0030479--C:actin cortical patch
GO:0016459--C:myosin complex
GO:0005524--F:ATP binding
GO:0003774--F:motor activity
KEGG afm:AFUA_8G05660
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002158 Ailuropoda melanoleuca 44.08 0.00e+00 752.00
IUUC-Apl-003803 Anas platyrhynchos 40.73 0.00e+00 759.00
IUUC-Aca-004926 Anolis carolinensis 39.95 0.00e+00 724.00
IUUC-Acl-008168 Aspergillus clavatus 92.82 0.00e+00 2113.00
IUUC-Afl-008552 Aspergillus flavus 85.99 0.00e+00 2041.00
IUUC-Ang-009818 Aspergillus niger 92.50 0.00e+00 1899.00
IUUC-Aor-009891 Aspergillus oryzae 85.83 0.00e+00 2037.00
IUUC-Ate-010325 Aspergillus terreus 91.06 0.00e+00 1875.00
IUUC-Ame-011036 Astyanax mexicanus 40.76 0.00e+00 786.00
IUUC-Bta-012409 Bos taurus 42.63 0.00e+00 765.00
IUUC-Cel-018582 Caenorhabditis elegans 38.87 0.00e+00 715.00
IUUC-Cja-019330 Callithrix jacchus 39.38 0.00e+00 742.00
IUUC-Cfa-020409 Canis familiaris 43.53 0.00e+00 754.00
IUUC-Cpo-021332 Cavia porcellus 41.08 0.00e+00 777.00
IUUC-Csa-023357 Chlorocebus sabaeus 39.95 0.00e+00 744.00
IUUC-Dre-027800 Danio rerio 45.02 0.00e+00 761.00
IUUC-Dno-029858 Dasypus novemcinctus 40.07 0.00e+00 745.00
IUUC-Dor-030253 Dipodomys ordii 40.65 3.00e-170 590.00
IUUC-Dse-031169 Dothistroma septosporum 45.10 5.00e-09 56.20
IUUC-Eca-034303 Equus caballus 43.28 0.00e+00 698.00
IUUC-Eeu-034561 Erinaceus europaeus 37.76 1.00e-49 190.00
IUUC-Fca-036174 Felis catus 41.12 0.00e+00 676.00
IUUC-Fal-037393 Ficedula albicollis 40.27 0.00e+00 760.00
IUUC-Gmo-038566 Gadus morhua 40.88 0.00e+00 659.00
IUUC-Gga-040323 Gallus gallus 44.75 0.00e+00 763.00
IUUC-Gac-042415 Gasterosteus aculeatus 39.30 0.00e+00 729.00
IUUC-Ggo-044547 Gorilla gorilla 39.90 0.00e+00 746.00
IUUC-Hsa-045712 Homo sapiens 44.03 0.00e+00 766.00
IUUC-Itr-048108 Ictidomys tridecemlineatus 42.76 0.00e+00 734.00
IUUC-Lch-050042 Latimeria chalumnae 39.19 0.00e+00 723.00
IUUC-Loc-052303 Lepisosteus oculatus 43.71 0.00e+00 762.00
IUUC-Laf-054148 Loxodonta africana 39.91 0.00e+00 744.00
IUUC-Mcc-054773 Macaca mulatta 43.48 0.00e+00 767.00
IUUC-Meu-056504 Macropus eugenii 39.60 6.00e-84 304.00
IUUC-Mmr-061357 Microcebus murinus 44.07 0.00e+00 763.00
IUUC-Mdo-062467 Monodelphis domestica 42.61 0.00e+00 752.00
IUUC-Mmu-063711 Mus musculus 43.72 0.00e+00 765.00
IUUC-Mpu-066658 Mustela putorius furo 44.09 0.00e+00 767.00
IUUC-Mlu-067569 Myotis lucifugus 41.51 9.00e-09 54.30
IUUC-Nfi-068411 Neosartorya fischeri 98.32 0.00e+00 2174.00
IUUC-Nle-070144 Nomascus leucogenys 39.98 0.00e+00 745.00
IUUC-Ont-071404 Oreochromis niloticus 43.06 0.00e+00 727.00
IUUC-Oan-073284 Ornithorhynchus anatinus 31.70 7.00e-22 96.70
IUUC-Ocu-074538 Oryctolagus cuniculus 40.12 0.00e+00 759.00
IUUC-Ola-087396 Oryzias latipes 40.44 0.00e+00 774.00
IUUC-Oga-088985 Otolemur garnettii 44.75 0.00e+00 765.00
IUUC-Oar-089527 Ovis aries 39.83 0.00e+00 723.00
IUUC-Ptr-090485 Pan troglodytes 39.90 0.00e+00 746.00
IUUC-Pan-092029 Papio anubis 40.23 0.00e+00 772.00
IUUC-Psi-094016 Pelodiscus sinensis 33.30 3.00e-134 471.00
IUUC-Pma-094458 Petromyzon marinus 43.36 0.00e+00 748.00
IUUC-Pfo-096486 Poecilia formosa 42.90 0.00e+00 728.00
IUUC-Pab-098517 Pongo abelii 39.55 0.00e+00 728.00
IUUC-Pca-100128 Procavia capensis 34.36 2.00e-67 249.00
IUUC-Pva-102994 Pteropus vampyrus 38.43 0.00e+00 696.00
IUUC-Rno-105992 Rattus norvegicus 43.78 0.00e+00 767.00
IUUC-Sha-107424 Sarcophilus harrisii 42.43 0.00e+00 745.00
IUUC-Ssc-115400 Sus scrofa 44.03 0.00e+00 768.00
IUUC-Tgu-116572 Taeniopygia guttata 39.79 0.00e+00 701.00
IUUC-Tru-117568 Takifugu rubripes 42.90 0.00e+00 722.00
IUUC-Tni-120087 Tetraodon nigroviridis 40.02 0.00e+00 748.00
IUUC-Tre-122048 Trichoderma reesei 67.36 0.00e+00 1488.00
IUUC-Tbe-127462 Tupaia belangeri 36.10 3.00e-105 374.00
IUUC-Ttr-128783 Tursiops truncatus 40.26 0.00e+00 739.00
IUUC-Vda-130020 Verticillium dahliae 68.17 0.00e+00 1460.00
IUUC-Xtr-131936 Xenopus tropicalis 40.13 0.00e+00 731.00
Created Date 25-Jun-2017

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