iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074126

Ensembl Protein ID

ENSOCUP00000000803.3

UniProt Accession

G1SEC9; G1SEC9_RABIT

Genbank Protein ID

ENSOCUP00000000803

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02014202

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000000931.3	ENSOCUT00000000930.3	ENSOCUP00000000803.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-38	129.0	206	241
UBD/Beta-Prp	3.80e-52	177.3	111	332

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvl 35
           gHt+  +c++f +d  +v++s+D t+ +WD+ tg +
   Q: 206  GHTGYLSCCRFlDDSQIVTSSGDTTCALWDIETGQQ 241
           8**********98899***************99976 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++    
   Q: 111  RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR 199
           446899*****************************************************************************987776 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               l gh+g  +c ++ + ++ +v++s D+t+ lWd++tg+  +t+tg h ++v sls++++++ +vsg++d + klwd++ g c ++
   Q: 200  vsrELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETGQQTTTFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQS 286
           6779*************99.67789***********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           ++gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++ 
   Q: 287  FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD 332
           **************************************99888874 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MLVHVLVQKR NLASGVSREE VTAALVPLQK FSRESSSCTA RKLGVGAMKG ILAVLLVSGE 60
VTDSRMSELE QLRQEAEQLR NQIQDARKAC NDATLVQITS NMDSVGRVQM RTRRTLRGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAAAGGAA GACCTTTCTC TCTCTCTCAC TGTCCACTCT CCTGTCGGAA ACAAAAAAAA 60
AACAATAAAA AAAATAAAAT GAACTGCCTG AAGTAGATGT GACTTTTTAT TTAATTTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	99.07	0.00e+00	669.00
IUUC-Apl-003923	Anas platyrhynchos	94.75	2.00e-176	610.00
IUUC-Aca-004754	Anolis carolinensis	94.74	5.00e-177	613.00
IUUC-Bta-013200	Bos taurus	99.07	0.00e+00	668.00
IUUC-Cja-019845	Callithrix jacchus	99.07	0.00e+00	668.00
IUUC-Cfa-020395	Canis familiaris	99.07	0.00e+00	669.00
IUUC-Cpo-021376	Cavia porcellus	98.45	0.00e+00	667.00
IUUC-Csa-023295	Chlorocebus sabaeus	99.38	0.00e+00	669.00
IUUC-Cho-024766	Choloepus hoffmanni	98.77	0.00e+00	671.00
IUUC-Dno-029802	Dasypus novemcinctus	98.68	0.00e+00	630.00
IUUC-Ete-032710	Echinops telfairi	96.10	1.00e-174	604.00
IUUC-Eca-033628	Equus caballus	98.76	0.00e+00	667.00
IUUC-Eeu-034978	Erinaceus europaeus	97.07	3.00e-152	530.00
IUUC-Fal-037616	Ficedula albicollis	95.05	9.00e-178	615.00
IUUC-Gga-040249	Gallus gallus	95.05	9.00e-178	615.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.64	2.00e-176	611.00
IUUC-Ggo-044954	Gorilla gorilla	99.07	0.00e+00	668.00
IUUC-Hsa-046105	Homo sapiens	99.38	0.00e+00	669.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	99.38	0.00e+00	667.00
IUUC-Mcc-055787	Macaca mulatta	99.38	0.00e+00	669.00
IUUC-Mga-060050	Meleagris gallopavo	94.75	2.00e-176	610.00
IUUC-Mmr-060931	Microcebus murinus	99.38	0.00e+00	669.00
IUUC-Mdo-063055	Monodelphis domestica	94.43	8.00e-177	612.00
IUUC-Mmu-064368	Mus musculus	96.59	0.00e+00	634.00
IUUC-Mpu-066358	Mustela putorius furo	99.07	0.00e+00	669.00
IUUC-Mlu-067328	Myotis lucifugus	98.14	0.00e+00	662.00
IUUC-Nle-069612	Nomascus leucogenys	99.38	0.00e+00	669.00
IUUC-Oan-072913	Ornithorhynchus anatinus	95.36	1.00e-178	618.00
IUUC-Ola-087297	Oryzias latipes	92.31	4.00e-177	613.00
IUUC-Oar-089360	Ovis aries	99.07	0.00e+00	668.00
IUUC-Ptr-091437	Pan troglodytes	99.38	0.00e+00	669.00
IUUC-Pan-092195	Papio anubis	99.07	0.00e+00	668.00
IUUC-Psi-093718	Pelodiscus sinensis	95.05	9.00e-178	615.00
IUUC-Pfo-096251	Poecilia formosa	92.26	4.00e-176	610.00
IUUC-Sce-106298	Saccharomyces cerevisiae	36.83	3.00e-67	248.00
IUUC-Sha-106534	Sarcophilus harrisii	94.43	4.00e-177	613.00
IUUC-Sar-113642	Sorex araneus	98.90	8.00e-156	542.00
IUUC-Tgu-117198	Taeniopygia guttata	95.05	9.00e-178	615.00
IUUC-Tsy-119354	Tarsius syrichta	96.28	0.00e+00	630.00
IUUC-Ttr-129243	Tursiops truncatus	99.38	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence