iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008237

Ensembl Protein ID

CADACLAP00007048

UniProt Accession

A1C6B0; A1C6B0_ASPCL

Genbank Protein ID

EAW13931.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

DS027045

Gene Name

ACLA_069610

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00007208	CADACLAT00007208	CADACLAP00007048

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-30	103.3	96	129
UBD/Beta-Prp	2.70e-65	219.4	13	295

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H d ++++a  ++ ++++++sdD tik+WD+ +g
   Q: 96   HPDYIRSIAVhPSqPFVLTASDDMTIKLWDWEKG 129
           99*******99777****************8765 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           +++++ ++f+p +++++t+ ++g + +w+++t++ +++++  + +v+a +f+ +++++v gs+D  ++v++++t++ + ++++h d+++s+++
   Q: 13   SERVKGIDFHPTEPWILTTLYSGHVYIWSYETQSIIKTFELTDVPVRAGRFIARKNWIVCGSDDFQLRVYNYNTSEKIASFEAHPDYIRSIAV 105
           678999*************************************************************************************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.. 192
           +ps+ +++++s+d ti++wd+e+g++  ++ +gh++ v++++++p++ n ++s++lDrtv++W+l +     tl+   t+ v+++++ ++   
   Q: 106  HPSQPFVLTASDDMTIKLWDWEKGWKCVQVYEGHSHYVMGLAINPKDtNTFASACLDRTVKIWSLGSPHANFTLEAHETKGVNHVDYYPQAdk 198
           ************************98888***********************************************99********8887777 PP
   S: 193  kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           ++l++ s+d+tvk+wd+ t+  + tl+ght+nv+    +p+   ++sgs+Dg+i++W   +  l ++l++  ++ ++va+ + g++ ++ g +
   Q: 199  PYLLTTSDDRTVKVWDYTTKALIATLEGHTSNVSFACYHPELPVIISGSEDGTIKLWHANTYRLEQSLSYGLERAWCVAY-QRGRQGIAMGFD 290
           *******************************************************************************9.666666665555 PP
   S: 286  dskvn 290
           d+ v 
   Q: 291  DGAVV 295
           55544 PP

Organism

Aspergillus clavatus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDVKRQLF ARSERVKGID FHPTEPWILT TLYSGHVYIW SYETQSIIKT FELTDVPVRA 60
GRFIARKNWI VCGSDDFQLR VYNYNTSEKI ASFEAHPDYI RSIAVHPSQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGATTGG ATGTCAAGGT ACGCATTTGT TTAAACATTT GCATTCTATG TTATCCCGTC 60
AACTGCTTCC TGTCTCGATT GGATGAAGGA AACGCCTGCT AATTGTAATT GCGACCCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

act:ACLA_069610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	46.06	0.00e+00	771.00
IUUC-Aml-002154	Ailuropoda melanoleuca	53.75	0.00e+00	979.00
IUUC-Atr-003090	Amborella trichopoda	54.59	0.00e+00	897.00
IUUC-Apl-003976	Anas platyrhynchos	56.51	0.00e+00	976.00
IUUC-Aca-004301	Anolis carolinensis	53.80	0.00e+00	983.00
IUUC-Aly-006508	Arabidopsis lyrata	50.51	0.00e+00	899.00
IUUC-Ath-007630	Arabidopsis thaliana	52.31	0.00e+00	904.00
IUUC-Ago-007914	Ashbya gossypii	50.18	0.00e+00	851.00
IUUC-Afl-008535	Aspergillus flavus	92.57	0.00e+00	1580.00
IUUC-Afu-008845	Aspergillus fumigatus	95.32	0.00e+00	1647.00
IUUC-Ani-009135	Aspergillus nidulans	89.71	0.00e+00	1534.00
IUUC-Ang-009654	Aspergillus niger	96.95	0.00e+00	1340.00
IUUC-Aor-009939	Aspergillus oryzae	93.33	0.00e+00	1675.00
IUUC-Ate-010355	Aspergillus terreus	93.50	0.00e+00	1576.00
IUUC-Ame-010922	Astyanax mexicanus	52.61	0.00e+00	855.00
IUUC-Bgr-012249	Blumeria graminis	78.08	0.00e+00	1339.00
IUUC-Bta-013579	Bos taurus	56.76	0.00e+00	894.00
IUUC-Bci-013866	Botrytis cinerea	78.86	0.00e+00	1353.00
IUUC-Bdi-015046	Brachypodium distachyon	52.11	0.00e+00	920.00
IUUC-Bol-015466	Brassica oleracea	51.73	0.00e+00	880.00
IUUC-Bra-016617	Brassica rapa	51.49	0.00e+00	875.00
IUUC-Cel-018387	Caenorhabditis elegans	51.22	0.00e+00	894.00
IUUC-Cja-019145	Callithrix jacchus	53.75	0.00e+00	978.00
IUUC-Cfa-020564	Canis familiaris	53.61	0.00e+00	979.00
IUUC-Cpo-022201	Cavia porcellus	53.86	0.00e+00	982.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	54.15	0.00e+00	866.00
IUUC-Csa-023383	Chlorocebus sabaeus	59.23	0.00e+00	751.00
IUUC-Cho-024454	Choloepus hoffmanni	53.12	0.00e+00	843.00
IUUC-Cin-025681	Ciona intestinalis	52.18	0.00e+00	892.00
IUUC-Csv-026012	Ciona savignyi	52.05	0.00e+00	894.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	73.90	0.00e+00	1221.00
IUUC-Cne-026986	Cryptococcus neoformans	56.99	0.00e+00	982.00
IUUC-Cme-027219	Cyanidioschyzon merolae	46.63	0.00e+00	791.00
IUUC-Dre-027846	Danio rerio	56.25	0.00e+00	976.00
IUUC-Dor-030462	Dipodomys ordii	54.35	0.00e+00	785.00
IUUC-Dse-031268	Dothistroma septosporum	78.07	0.00e+00	1353.00
IUUC-Dme-031791	Drosophila melanogaster	52.93	0.00e+00	903.00
IUUC-Ete-033166	Echinops telfairi	52.86	0.00e+00	627.00
IUUC-Eca-034180	Equus caballus	52.39	0.00e+00	937.00
IUUC-Eeu-035086	Erinaceus europaeus	42.37	4.00e-105	374.00
IUUC-Fca-036265	Felis catus	53.61	0.00e+00	979.00
IUUC-Fal-037202	Ficedula albicollis	55.88	0.00e+00	931.00
IUUC-Fox-037711	Fusarium oxysporum	78.66	0.00e+00	1262.00
IUUC-Fso-038268	Fusarium solani	77.93	0.00e+00	1252.00
IUUC-Gmo-039046	Gadus morhua	56.12	0.00e+00	971.00
IUUC-Ggr-039863	Gaeumannomyces graminis	79.78	0.00e+00	1320.00
IUUC-Gga-041112	Gallus gallus	53.75	0.00e+00	979.00
IUUC-Gac-041733	Gasterosteus aculeatus	53.85	0.00e+00	949.00
IUUC-Gma-044333	Glycine max	52.29	0.00e+00	922.00
IUUC-Ggo-044984	Gorilla gorilla	56.63	0.00e+00	979.00
IUUC-Hsa-046698	Homo sapiens	56.51	0.00e+00	979.00
IUUC-Hvu-047669	Hordeum vulgare	61.58	1.00e-142	497.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	53.75	0.00e+00	978.00
IUUC-Kpa-049265	Komagataella pastoris	56.53	0.00e+00	977.00
IUUC-Lch-050473	Latimeria chalumnae	55.99	0.00e+00	970.00
IUUC-Lpe-051579	Leersia perrieri	51.98	0.00e+00	915.00
IUUC-Loc-052675	Lepisosteus oculatus	56.12	0.00e+00	975.00
IUUC-Lma-053218	Leptosphaeria maculans	74.85	0.00e+00	1261.00
IUUC-Laf-053757	Loxodonta africana	53.50	0.00e+00	970.00
IUUC-Mcc-054859	Macaca mulatta	53.75	0.00e+00	979.00
IUUC-Meu-056174	Macropus eugenii	44.16	5.00e-92	330.00
IUUC-Mor-057264	Magnaporthe oryzae	79.54	0.00e+00	1299.00
IUUC-Mpo-057538	Magnaporthe poae	79.90	0.00e+00	1344.00
IUUC-Mtr-058310	Medicago truncatula	52.67	0.00e+00	917.00
IUUC-Mla-058937	Melampsora laricipopulina	56.54	0.00e+00	968.00
IUUC-Mga-059875	Meleagris gallopavo	53.50	0.00e+00	972.00
IUUC-Mvi-060240	Microbotryum violaceum	57.97	0.00e+00	990.00
IUUC-Mmr-061261	Microcebus murinus	53.61	0.00e+00	979.00
IUUC-Mdo-062076	Monodelphis domestica	53.86	0.00e+00	983.00
IUUC-Mmu-063324	Mus musculus	53.86	0.00e+00	981.00
IUUC-Mac-064636	Musa acuminata	50.69	0.00e+00	899.00
IUUC-Mpu-065961	Mustela putorius furo	53.61	0.00e+00	979.00
IUUC-Mlu-067059	Myotis lucifugus	55.87	0.00e+00	944.00
IUUC-Nfi-068277	Neosartorya fischeri	95.66	0.00e+00	1642.00
IUUC-Ncr-068659	Neurospora crassa	75.12	0.00e+00	1319.00
IUUC-Nle-069034	Nomascus leucogenys	53.75	0.00e+00	979.00
IUUC-Opr-070334	Ochotona princeps	57.59	0.00e+00	923.00
IUUC-Ont-071563	Oreochromis niloticus	56.51	0.00e+00	972.00
IUUC-Oan-073416	Ornithorhynchus anatinus	56.91	0.00e+00	937.00
IUUC-Ocu-074522	Oryctolagus cuniculus	53.50	0.00e+00	975.00
IUUC-Oba-075760	Oryza barthii	50.88	0.00e+00	890.00
IUUC-Obr-076201	Oryza brachyantha	52.10	0.00e+00	911.00
IUUC-Ogl-077450	Oryza glaberrima	51.47	0.00e+00	912.00
IUUC-Ogu-078994	Oryza glumaepatula	50.88	0.00e+00	889.00
IUUC-Oin-079856	Oryza indica	51.30	0.00e+00	896.00
IUUC-Olo-080731	Oryza longistaminata	51.34	0.00e+00	875.00
IUUC-Ome-081554	Oryza meridionalis	48.42	0.00e+00	833.00
IUUC-Oni-082324	Oryza nivara	50.88	0.00e+00	888.00
IUUC-Opu-083400	Oryza punctata	49.60	0.00e+00	883.00
IUUC-Oru-084829	Oryza rufipogon	50.88	0.00e+00	889.00
IUUC-Osa-086026	Oryza sativa	51.71	0.00e+00	917.00
IUUC-Ola-087245	Oryzias latipes	53.50	0.00e+00	974.00
IUUC-Olu-087655	Ostreococcus lucimarinus	54.14	0.00e+00	915.00
IUUC-Oga-088163	Otolemur garnettii	51.52	0.00e+00	932.00
IUUC-Oar-089842	Ovis aries	53.61	0.00e+00	979.00
IUUC-Ptr-090501	Pan troglodytes	53.75	0.00e+00	980.00
IUUC-Pan-092011	Papio anubis	53.75	0.00e+00	978.00
IUUC-Psi-093308	Pelodiscus sinensis	53.63	0.00e+00	976.00
IUUC-Pma-094695	Petromyzon marinus	55.28	0.00e+00	909.00
IUUC-Pno-094785	Phaeosphaeria nodorum	79.58	1.00e-139	488.00
IUUC-Ppa-095638	Physcomitrella patens	53.93	0.00e+00	928.00
IUUC-Pfo-096587	Poecilia formosa	56.51	0.00e+00	975.00
IUUC-Pab-097926	Pongo abelii	54.95	0.00e+00	902.00
IUUC-Pop-099634	Populus trichocarpa	52.81	0.00e+00	920.00
IUUC-Pca-100965	Procavia capensis	55.36	0.00e+00	941.00
IUUC-Ppe-101470	Prunus persica	52.56	0.00e+00	923.00
IUUC-Pva-102451	Pteropus vampyrus	53.60	0.00e+00	773.00
IUUC-Pgr-103453	Puccinia graminis	58.62	0.00e+00	1010.00
IUUC-Ptt-103868	Puccinia triticina	58.50	0.00e+00	1007.00
IUUC-Pte-104274	Pyrenophora teres	77.32	0.00e+00	1307.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	73.21	0.00e+00	1243.00
IUUC-Rno-105979	Rattus norvegicus	49.11	0.00e+00	739.00
IUUC-Sce-106269	Saccharomyces cerevisiae	50.61	0.00e+00	875.00
IUUC-Sha-106905	Sarcophilus harrisii	53.86	0.00e+00	982.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	53.29	0.00e+00	896.00
IUUC-Spo-108299	Schizosaccharomyces pombe	53.09	0.00e+00	920.00
IUUC-Smo-108695	Selaginella moellendorffii	51.78	0.00e+00	902.00
IUUC-Sit-110239	Setaria italica	51.14	0.00e+00	922.00
IUUC-Sly-111775	Solanum lycopersicum	53.87	0.00e+00	917.00
IUUC-Stu-112906	Solanum tuberosum	53.00	0.00e+00	827.00
IUUC-Sar-113472	Sorex araneus	52.98	0.00e+00	704.00
IUUC-Sbi-113886	Sorghum bicolor	53.41	0.00e+00	915.00
IUUC-Sre-115040	Sporisorium reilianum	56.77	0.00e+00	1000.00
IUUC-Ssc-115593	Sus scrofa	53.50	0.00e+00	978.00
IUUC-Tgu-117239	Taeniopygia guttata	56.38	0.00e+00	976.00
IUUC-Tru-118025	Takifugu rubripes	53.20	0.00e+00	969.00
IUUC-Tsy-118824	Tarsius syrichta	52.54	0.00e+00	712.00
IUUC-Tni-120142	Tetraodon nigroviridis	53.50	0.00e+00	967.00
IUUC-Tca-121613	Theobroma cacao	52.39	0.00e+00	924.00
IUUC-Tre-122072	Trichoderma reesei	77.56	0.00e+00	1316.00
IUUC-Tvi-122546	Trichoderma virens	77.37	0.00e+00	1312.00
IUUC-Tae-125395	Triticum aestivum	52.65	0.00e+00	912.00
IUUC-Tur-126283	Triticum urartu	46.30	0.00e+00	769.00
IUUC-Tme-127041	Tuber melanosporum	76.40	0.00e+00	1330.00
IUUC-Tbe-127770	Tupaia belangeri	55.26	0.00e+00	809.00
IUUC-Ttr-129294	Tursiops truncatus	53.50	0.00e+00	975.00
IUUC-Uma-129351	Ustilago maydis	56.14	0.00e+00	997.00
IUUC-Vda-129716	Verticillium dahliae	79.42	0.00e+00	1379.00
IUUC-Vpa-130037	Vicugna pacos	45.75	5.00e-113	400.00
IUUC-Vvi-131689	Vitis vinifera	52.50	0.00e+00	921.00
IUUC-Xtr-132633	Xenopus tropicalis	56.74	0.00e+00	975.00
IUUC-Xma-133347	Xiphophorus maculatus	56.38	0.00e+00	973.00
IUUC-Yli-134455	Yarrowia lipolytica	59.50	0.00e+00	981.00
IUUC-Zma-135867	Zea mays	52.40	0.00e+00	937.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence