iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115908

Ensembl Protein ID

ENSSSCP00000020119.1

UniProt Accession

I3L7W1; I3L7W1_PIG

Genbank Protein ID

ENSSSCP00000020119

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AEMK01196757

Gene Name

UCHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000022945.1	ENSSSCT00000024016.1	ENSSSCP00000020119.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	78.22	8.00e-98	353.00	IUUC-Hsa-045820
DUB/UCH	78.22	8.00e-98	353.00	IUUC-Hsa-045820
UBD/Other/Other	78.22	8.00e-98	353.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MQLKPMEINP ELLCVFLKRL IIEAHWSPFA EVAGVSGQSL GQYPRPLCSL HFVFERHSQH 60
ENFRKKQIEE LKGQEVSPKV YFMKQTIGNS CGTIGLIHAV ANNQDKLEFE DGSVLKQFLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTCA AACCGATGGA GATTAACCCG GAGGTGAGTG TCAGGTGCAC GGTTACCCAG 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0044306--C:neuron projection terminus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0016874--F:ligase activity
GO:0008242--F:omega peptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007628--P:adult walking behavior
GO:0007412--P:axon target recognition
GO:0019896--P:axonal transport of mitochondrion
GO:0008283--P:cell proliferation
GO:0042755--P:eating behavior
GO:0048747--P:muscle fiber development
GO:0043407--P:negative regulation of MAP kinase activity
GO:0050905--P:neuromuscular process
GO:0016579--P:protein deubiquitination
GO:0002931--P:response to ischemia
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	69.38	6.00e-92	329.00
IUUC-Apl-003693	Anas platyrhynchos	58.41	2.00e-69	254.00
IUUC-Aca-004716	Anolis carolinensis	61.50	2.00e-75	275.00
IUUC-Ame-011806	Astyanax mexicanus	56.44	7.00e-66	243.00
IUUC-Bta-013521	Bos taurus	69.88	2.00e-92	331.00
IUUC-Cja-019642	Callithrix jacchus	78.67	2.00e-94	337.00
IUUC-Cfa-020442	Canis familiaris	80.09	3.00e-95	340.00
IUUC-Cpo-021723	Cavia porcellus	91.02	4.00e-85	306.00
IUUC-Csa-023626	Chlorocebus sabaeus	78.67	2.00e-94	337.00
IUUC-Cho-024548	Choloepus hoffmanni	65.14	2.00e-31	127.00
IUUC-Dre-027854	Danio rerio	54.87	2.00e-64	238.00
IUUC-Dno-029325	Dasypus novemcinctus	78.67	3.00e-95	340.00
IUUC-Dor-030114	Dipodomys ordii	77.78	3.00e-99	353.00
IUUC-Ete-033092	Echinops telfairi	70.67	5.00e-83	299.00
IUUC-Eca-033854	Equus caballus	90.21	1.00e-70	257.00
IUUC-Eeu-034493	Erinaceus europaeus	78.67	9.00e-94	335.00
IUUC-Gmo-038848	Gadus morhua	50.47	7.00e-56	209.00
IUUC-Gga-041078	Gallus gallus	60.18	1.00e-75	275.00
IUUC-Gac-042064	Gasterosteus aculeatus	51.80	1.00e-58	219.00
IUUC-Ggo-044827	Gorilla gorilla	78.22	5.00e-94	336.00
IUUC-Hsa-045820	Homo sapiens	78.22	5.00e-94	336.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	80.00	5.00e-96	342.00
IUUC-Lch-050121	Latimeria chalumnae	60.71	2.00e-76	278.00
IUUC-Loc-052342	Lepisosteus oculatus	58.77	4.00e-71	260.00
IUUC-Laf-053916	Loxodonta africana	77.09	5.00e-93	333.00
IUUC-Mcc-054838	Macaca mulatta	78.67	2.00e-94	337.00
IUUC-Meu-056478	Macropus eugenii	73.78	2.00e-94	337.00
IUUC-Mga-059878	Meleagris gallopavo	58.56	5.00e-70	256.00
IUUC-Mdo-062544	Monodelphis domestica	72.89	3.00e-88	317.00
IUUC-Mmu-063300	Mus musculus	79.11	2.00e-100	357.00
IUUC-Mpu-066128	Mustela putorius furo	76.24	1.00e-80	292.00
IUUC-Mlu-067778	Myotis lucifugus	78.67	8.00e-100	355.00
IUUC-Nle-069686	Nomascus leucogenys	78.22	4.00e-94	336.00
IUUC-Opr-070535	Ochotona princeps	71.11	4.00e-85	306.00
IUUC-Ont-071510	Oreochromis niloticus	51.79	6.00e-62	229.00
IUUC-Ocu-074590	Oryctolagus cuniculus	78.22	2.00e-94	337.00
IUUC-Ola-087552	Oryzias latipes	48.50	3.00e-57	214.00
IUUC-Oga-089013	Otolemur garnettii	71.26	3.00e-90	324.00
IUUC-Oar-089861	Ovis aries	70.47	6.00e-93	333.00
IUUC-Ptr-091536	Pan troglodytes	77.78	2.00e-93	334.00
IUUC-Pan-092909	Papio anubis	78.67	2.00e-94	337.00
IUUC-Psi-093818	Pelodiscus sinensis	64.16	1.00e-77	281.00
IUUC-Pab-098048	Pongo abelii	78.22	5.00e-94	336.00
IUUC-Pca-100818	Procavia capensis	53.30	6.00e-44	169.00
IUUC-Pva-102954	Pteropus vampyrus	77.78	5.00e-92	329.00
IUUC-Rno-105966	Rattus norvegicus	79.11	2.00e-100	357.00
IUUC-Sha-107111	Sarcophilus harrisii	81.93	9.00e-78	281.00
IUUC-Sar-113190	Sorex araneus	66.96	7.00e-32	128.00
IUUC-Tsy-119561	Tarsius syrichta	71.11	9.00e-84	302.00
IUUC-Tbe-128048	Tupaia belangeri	89.16	4.00e-83	299.00
IUUC-Ttr-128494	Tursiops truncatus	79.46	5.00e-94	336.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence